Antioxidant and protective effects of extra virgin olive oil incorporated with diallyl sulfide against CCl<sub>4</sub>‐induced acute liver injury in mice

Habibi, Emna; Baâti, Tarek; Njim, Leïla; M’Rabet, Yassine; Hosni, Karim

doi:10.1002/fsn3.2638

Cited by 10 publications

(3 citation statements)

References 54 publications

(88 reference statements)

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“…Furthermore, it has been shown to be effective in preventing osteoporosis, as reported by (García-Gavilán et al, 2018). Additionally, the hepatoprotective and anti-inflammatory benefits have been observed in intoxicated mice which is attributed to the antioxidant activity of olive oil (Habibi et al, 2021).…”

Section: Demonstrated How Pbmentioning

confidence: 78%

Ameliorative effects of virgin olive oil, propolis, and zinc chloride on lead acetate-induced genetic variation in mice using 16S rRNA sequence

Mahrous

Noseer

2023

SVU-International Journal of Veterinary Sciences

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Lead acetate poses numerous health risks and seriously harms living things' genetic makeup. Propolis and virgin olive oil (VOO) are both natural materials that contain anti-genotoxic chemicals as well as a variety of other advantageous properties for 16S rRNA sequencing. The current study was designated to determine the beneficial effects of virgin olive oil and propolis on lead acetate-induced genotoxicity in mice. Twenty-five male albino mice (Mus musculus) were divided into five groups of five mice each: the first group served as the control and received no treatment; the second, third, fourth, and fifth groups received 400 mg/kg B.W. of lead acetate orally, either dissolved in distilled water or dissolved in 8 mL/kg of VOO, or dissolved in 150 mg/kg of propolis, or 4 mg/kg B.W. of zinc chloride (ZnCl2), respectively. The second group exhibited a high genetic distance value, while the fifth group exhibited a low genetic distance value when compared with the control group. Propolis and virgin olive oil were found to be effective in lowering the genetic variation caused by lead acetate, with genetic distances of 0.0018 and 0.0026, respectively, according to the 16S rRNA sequence data. It concluded that propolis and virgin oil reduced lead acetate genotoxicity when compared with zinc chloride.

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Section: Demonstrated How Pbmentioning

confidence: 78%

Ameliorative effects of virgin olive oil, propolis, and zinc chloride on lead acetate-induced genetic variation in mice using 16S rRNA sequence

Mahrous

Noseer

2023

SVU-International Journal of Veterinary Sciences

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“…HT helps to avoid liver steatosis and the mitochondrial dysfunction that comes with it, both of which are caused by [145] [146]…”

Section: Mufas Can Potentially Inhibit Tumor Growth and Proliferationmentioning

confidence: 99%

Virgin Olive Oil, A Rich Source of Functional Bioactive Compounds in the Promotion of Human Health: An Overview

Maazoun

Aounallah

Damergi

et al. 2021

EJNFS

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The prevention of pathologies by diet management is an important public health challenge. The Mediterranean diet (Med diet) is considered one of the healthiest dietary patterns. According to current scientific research, this dietary pattern is linked to a decreased prevalence and incidence of various chronic diseases, including cardiovascular disease, diabetes, cancer, and age-related cognitive decline, as well as a lower overall mortality rate. In the Mediterranean diet, a high consumption of Virgin Olive Oil (VOO), fruit, nuts, vegetables, and grains is linked to a decreased incidence of many diseases and a longer life expectancy. According to numerous studies, VOO is the major food responsible for the health and nutritional benefits of the Mediterranean diet. VOO chemical compounds have been shown in vitro and in vivo investigations to have potentially favorable health benefits as a result of their biological activities. VOO composition has been linked to a variety of biological activities, including antioxidant, anti-inflammatory, anti-diabetic, anti-cancer, and antiviral characteristics. As a result, increasing attention is being paid to the composition of VOO and the identification of its biologically active components. Because of their antioxidant, anti-inflammatory, and anti-thrombotic properties, phytochemicals, particularly phenolic compounds, have health-promoting effects, especially on cardiovascular and metabolic illnesses. These characteristics are even more important in light of the COVID-19 severe illness's heightened inflammatory and pro-thrombotic consequences. This overview collects and discusses the scattered data available in the literature concerning VOO compounds of biological interest and highlights their possible mechanisms of action and effects on human health. In vitro studies and in vivo intervention trials were selected and included in the study after conducting literature searches through "PubMed" and "Web of Science." In the majority of investigations, the ability of VOO phytochemicals to prevent the oxidation process at both the initiation and promotion/progression phases of several pathologies has been verified. The health benefits discussed in this article support the prospective health benefits acquired from VOO as a possible candidate in developing pharmaceutical preparations and nutraceutical or functional foods for a variety of pathological disorders. This idea could pave the way for future in vivo research and, eventually, clinical trials. In addition, greater research into the mechanisms of action and efficacy is needed to clarify the real biological potential of VOO phytochemicals on humans by performing intervention studies on populations at high disorder risk.

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“…These mechanisms have been shown to effectively mitigate cellular damage ( Ajibade et al, 2022 ; Caporali et al, 2022 ). Previous research has demonstrated that Lut exhibits the potential to mitigate the presence of inflammatory mediators through the elimination of free radicals, thereby offering therapeutic benefits in the treatment of carbon tetrachloride ( Habibi et al, 2021 ), mercury ( Tan et al, 2018 ), arsenic ( Quiller et al, 2018 ), and lead ( Baty et al, 2020 ) poisoning. Additionally, Lut has been shown to enhance energy supply and exert a protective role ( Zhang et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

The protective effect of Luteolin on chicken spleen lymphocytes from ammonia poisoning through mitochondria and balancing energy metabolism disorders

Chen,

Shen,

Liu

et al. 2023

Poultry Science

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Antioxidant and protective effects of extra virgin olive oil incorporated with diallyl sulfide against CCl₄‐induced acute liver injury in mice

Cited by 10 publications

References 54 publications

Ameliorative effects of virgin olive oil, propolis, and zinc chloride on lead acetate-induced genetic variation in mice using 16S rRNA sequence

Ameliorative effects of virgin olive oil, propolis, and zinc chloride on lead acetate-induced genetic variation in mice using 16S rRNA sequence

Virgin Olive Oil, A Rich Source of Functional Bioactive Compounds in the Promotion of Human Health: An Overview

The protective effect of Luteolin on chicken spleen lymphocytes from ammonia poisoning through mitochondria and balancing energy metabolism disorders

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Antioxidant and protective effects of extra virgin olive oil incorporated with diallyl sulfide against CCl4‐induced acute liver injury in mice

Cited by 10 publications

References 54 publications

Ameliorative effects of virgin olive oil, propolis, and zinc chloride on lead acetate-induced genetic variation in mice using 16S rRNA sequence

Ameliorative effects of virgin olive oil, propolis, and zinc chloride on lead acetate-induced genetic variation in mice using 16S rRNA sequence

Virgin Olive Oil, A Rich Source of Functional Bioactive Compounds in the Promotion of Human Health: An Overview

The protective effect of Luteolin on chicken spleen lymphocytes from ammonia poisoning through mitochondria and balancing energy metabolism disorders

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Product

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Antioxidant and protective effects of extra virgin olive oil incorporated with diallyl sulfide against CCl₄‐induced acute liver injury in mice