2022
DOI: 10.3390/molecules27185902
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Antioxidant, Antidiabetic, Anticholinergic, and Antiglaucoma Effects of Magnofluorine

Abstract: Magnofluorine, a secondary metabolite commonly found in various plants, has pharmacological potential; however, its antioxidant and enzyme inhibition effects have not been investigated. We investigated the antioxidant potential of Magnofluorine using bioanalytical assays with 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), N,N-dimethyl-p-phenylenediamine dihydrochloride (DMPD•+), and 1,1-diphenyl-2-picrylhydrazyl (DPPH•) scavenging abilities and K3[Fe(CN)6] and Cu2+ reduction abilities. Further… Show more

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Cited by 43 publications
(22 citation statements)
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“…The DPPH has been widely used for the measurement of free radical scavenging activity of samples ( Durmaz et al, 2022 ; Gülçin et al, 2022 ). To prepare stock solution, 4 mg of DPPH was mixed in 100 mL of methanol.…”
Section: Quantitative Analysismentioning
confidence: 99%
See 1 more Smart Citation
“…The DPPH has been widely used for the measurement of free radical scavenging activity of samples ( Durmaz et al, 2022 ; Gülçin et al, 2022 ). To prepare stock solution, 4 mg of DPPH was mixed in 100 mL of methanol.…”
Section: Quantitative Analysismentioning
confidence: 99%
“…Diabetes and obesity are the paramount recurrent endocrinemetabolic disorders that are categorized by hyperglycemia and impaired insulin secretion and/or its action (Kiziltas et al, 2022;Mutlu et al, 2023). Loss of β-cells function and impaired insulin secretion in obesity and diabetes results in persistent hyperglycemia and dyslipidemia (Eguchi et al, 2021).…”
Section: Introductionmentioning
confidence: 99%
“…They also maintain fluid balance throughout the body, especially in the eyes, kidneys, and stomach. High intraocular pressure (IOP) due to glaucoma (IOP) can be relieved with the use of inhibitors of carbonic anhydrase (CAIs) [ 35 ].…”
Section: Introductionmentioning
confidence: 99%
“…Thus, strategies to inhibit cholinergic acetylcholinesterase (AChE) in brain tissue have gained importance [ 24 , 25 ]. AChE, a hydrolytic enzyme, converts ACh to acetate and choline (Ch), whereas butyrylcholinesterase (BChE) converts butyrylcholine (BCh) to butyrate and Ch [ 26 ]. AD is clinically affected by brain tissue damage caused by ACh deficiency [ 27 ].…”
Section: Introductionmentioning
confidence: 99%