Antioxidant capacity and amino acid analysis of Caralluma adscendens (Roxb.) Haw var. fimbriata (wall.) Grav. &amp; Mayur. aerial parts

Maheshu, Vellingiri; Priyadarsini, Deivamarudhachalam Teepica; Sasikumar, J. M.

doi:10.1007/s13197-012-0761-5

Cited by 18 publications

(14 citation statements)

References 34 publications

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“…fimbriata. 32 Our results are in agreement with the reports of Chew et al (2009), 33 that methanol showed better recoveries and it is specifically effective in extracting polyphenols. Thus, solvents polarity plays a major role in extraction of the antioxidants.…”

Section: Discussionsupporting

confidence: 93%

Antioxidant potential and amino acid analysis of underutilized tropical fruit Limonia acidissima L.

Darsini

Maheshu

Vishnupriya

et al. 2013

Free Radicals and Antioxidants

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Objective: Limonia acidissima L. an underutilized edible fruit was evaluated for its antioxidant activity, free radical scavenging ability, proximate and amino acid analysis using established in vitro assay models. Methods: 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, trolox equivalent antioxidant capacity (TEAC) assay, hydroxyl radical scavenging activity (HRSA), ferric reducing antioxidant power (FRAP) assay, nitric oxide radical (NO) scavenging activity, total antioxidant activity (TAA) were carried out. The total phenolic (TP) and flavonoid contents (TF) of the extracts were determined and expressed as gallic acid and quercetin equivalents. Results: The highest percentage of phenol and flavonoid contents were observed in methanol and the lowest content was found in chloroform extract. Also, methanol extract recorded higher activity in DPPH , HRSA, FRAP and TAA whereas, ethyl acetate extract of the fruit was found to be active for ABTS þ radical scavenging activity. Further, water extract of the fruit exhibited potentially high nitric oxide radical scavenging activity than other solvent extracts. Moreover, the phenolic and flavonoid contents of the fruit extract significantly correlated with antioxidant capacity. Amino acid analysis revealed that among, all essential amino acids, the concentrations of isoleucine, phenylalanine and tryptophan were found to be present in higher amounts. Conclusion: Positive correlation was observed between polyphenolic contents and the antioxidant capacities. It is evident from the study that the fruit possess potent antioxidant activity with enormous health benefits and thus may be used in food and pharmaceutical applications.

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Section: Discussionsupporting

confidence: 93%

Antioxidant potential and amino acid analysis of underutilized tropical fruit Limonia acidissima L.

Darsini

Maheshu

Vishnupriya

et al. 2013

Free Radicals and Antioxidants

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“…It is worth noting that C. europaea is rich in phenolic compounds; the total phenolic content of C. europaea hydroethanolic extract was 51.42 ± 0.003 mg GAE/g dry of extract. ese values were significantly higher than those of the methanolic and aqueous extract of C. adscendens, being 21.0 ± 0.59 and 18.8 ± 0.98 mg GAE/g dry extract, respectively [33].…”

Section: Discussionmentioning

confidence: 69%

Phytochemical Study on Antioxidant and Antiproliferative Activities of Moroccan Caralluma europaea Extract and Its Bioactive Compound Classes

Amrati

Bourhia

Slighoua

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Background. Caralluma europaea (C. europaea) is a medicinal plant used in Moroccan popular medicine. Objective of the Study. The present work was aimed at identifying the chemical composition and the antioxidant and antiproliferative activities of hydroethanolic and bioactive compound classes of C. europaea. Materials and Methods. The chemical composition was analyzed using HPLC. The antioxidant power was determined using both DPPH and FRAP assays. The antiproliferative activity was effectuated against cancerous cells using WST-1. Results. The chemical analysis showed the presence of bioactive constituents such as quercetin, myricetin, and hesperetin. The polyphenol and flavonoid contents were estimated at 51.42 mg GA/g and 20.06 mg EQ/g, respectively. The EC50 values of FRAP assay of hydroethanolic, flavonoid, saponin, and mucilage extracts were 5.196 mg/ml, 4.537 mg/ml, 3.05 mg/ml, and 6.02 mg/ml, respectively. The obtained IC50 values with the DPPH test were 1.628 mg/ml, 1.05 mg/ml, 1.94 mg/ml, and 9.674 mg/ml, respectively. Regarding MDA-MB-231, saponins were highly effective even with the lowest concentration (15.62 μg/ml). The flavonoids decreased the cell viability with IC50 values of 43.62 ± 0.06 μg/ml, whereas the hydroethanolic extract and mucilages were ineffective. Saponins were also effective against MCF-7 cells with IC50 values of 4.195 ± 0.025 μg/ml. Conclusion. The present results suggest that C. europaea may have considerable potential for the development of effective natural anticancer agents.

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“…Through this type of studies, certain extracts and their components can be recommended for use an additive in food preparations and nutraceuticals [39]. Al-Attabi et al [40] reported that the ethanol extract and ethyl acetate fraction from C. arabica have strong antioxidant activity.…”

Section: Total Phenol and Flavonoid Contentsmentioning

confidence: 99%

Free-radical-scavenging and antioxidant capacities with special emphasis on enzyme activities andin vitrostudies inCaralluma flavaN. E. Br.

Karthishwaran

Shamisi

Kurup

et al. 2017

Biotechnology & Biotechnological Equipment

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Caralluma flava is a perennial, succulent edible plant distributed in the hillsides of the United Arab Emirates. In order to validate its use in the traditional system as an edible and medicinal source, we evaluated the antioxidant and in vitro free-radical-scavenging properties of its ethanol extract. The antioxidant activity of the extract was evaluated in vitro by 2,2'-azino-bis-3-ethylbenzothiazoline-6sulfonic acid (ABTS + ), 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), hydroxyl radical and nitric oxide radical scavenging assays. The antioxidant enzyme activities (superoxide dismutase, catalase and glutathione peroxidase) and non-enzymatic antioxidant contents (total reduced glutathione, and Vitamin E and Vitamin C) in the extracts were also determined. The total phenolics content of the plant extract was 10.14 mg/g and the flavonoid content was 4.13 mg/g. The results showed a positive linear correlation between these phytochemicals and the free-radical-scavenging activities. The C. flava extract exhibited significant radical-scavenging properties in the ABTS( + ), DPPH( ), hydroxyl radical and nitric oxide radical assays. The study revealed that C. flava could be considered an excellent source of enzymatic and non-enzymatic antioxidants. The results indicate that the plant extract has potent free-radical-scavenging activity and ability to prevent radical chain reactions. Based on the results obtained, C. flava seems to be a very promising species for further investigation in order to identify the compounds responsible for its biological activity.

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Antioxidant capacity and amino acid analysis of Caralluma adscendens (Roxb.) Haw var. fimbriata (wall.) Grav. & Mayur. aerial parts

Cited by 18 publications

References 34 publications

Antioxidant potential and amino acid analysis of underutilized tropical fruit Limonia acidissima L.

Antioxidant potential and amino acid analysis of underutilized tropical fruit Limonia acidissima L.

Phytochemical Study on Antioxidant and Antiproliferative Activities of Moroccan Caralluma europaea Extract and Its Bioactive Compound Classes

Free-radical-scavenging and antioxidant capacities with special emphasis on enzyme activities andin vitrostudies inCaralluma flavaN. E. Br.

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