Antioxidant, cytotoxic and antibacterial activity of Rosmarinus officinalis L. essential oil against bacteria isolated from urinary tract infection

Zuhairi, Jawad J. Mohammed J. Al; Kashi, Fereshteh Jookar; Rahimi-Moghaddam, Akram; Yazdani, Morteza

doi:10.1016/j.eujim.2020.101192

Cited by 37 publications

(17 citation statements)

References 30 publications

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“…As a superficial skin infection, PK is an easily accessible target for topical medications, and EO-based gels and ointments are potential therapeutic candidates [20]. The 12 EOs for our antibacterial study were chosen based on earlier publications reporting their antibacterial features [21][22][23][24][25][26][27][28][29][30]. No data were available concerning the sensitivities of the known aetiological agents of PK (B. thuringiensis, Kytococcus sedentarius and Dermatophilus congolensis).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Effect of Lemongrass (Cymbopogon citratus) against the Aetiological Agents of Pitted Keratolyis

et al. 2022

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Pitted keratolysis (PK) is a bacterial skin infection mostly affecting the pressure-bearing areas of the soles, causing unpleasant symptoms. Antibiotics are used for therapy, but the emergence of antiobiotic resistance, makes the application of novel topical therapeutic agents necessary. The antibacterial effects of 12 EOs were compared in the first part of this study against the three known aetiological agents of PK (Kytococcus sedentarius, Dermatophilus congolensis and Bacillus thuringiensis). The results of the minimal inhibitory concentration, minimal bactericidal concentration and spore-formation inhibition tests revealed that lemongrass was the most effective EO against all three bacterium species and was therefore chosen for further analysis. Seventeen compounds were identified with solid-phase microextraction followed by gas chromatography–mass spectrometry (HS-SPME/GC-MS) analysis while thin-layer chromatography combined with direct bioautography (TLC-BD) was used to detect the presence of antibacterially active compounds. Citral showed a characteristic spot at the Rf value of 0.47, while the HS-SPME/GC-MS analysis of an unknown spot with strong antibacterial activity revealed the presence of α-terpineol, γ-cadinene and calamenene. Of these, α-terpineol was confirmed to possess an antimicrobial effect on all three bacterium species associated with PK. Our study supports the hypothesis that, based on their spectrum, EO-based formulations have potent antibacterial effects against PK and warrant further investigation as topical therapeutics.

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Section: Discussionmentioning

confidence: 99%

Antibacterial Effect of Lemongrass (Cymbopogon citratus) against the Aetiological Agents of Pitted Keratolyis

et al. 2022

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“…The maximum trapping capacity of the oils collected during the flowering phase for the two sampling locations could be explained by the richness of EO in 1.8 cineol, camphene, borneol and camphor compounds [ 46 ]. Although camphor and 1,8 cineole were reported as the principal antioxidant in rosemary EO [ 47 ] and, also, other compounds as the α-pinene, β-pinene, and 1,8-cineole compounds [ 48 ]. It has been noted a correlation between antioxidant components including 1,8-cineole, α-pinene, camphor, borneol, and transcaryophyllene and the antioxidant activity [ 48 ].…”

Section: Resultsmentioning

confidence: 99%

“…Although camphor and 1,8 cineole were reported as the principal antioxidant in rosemary EO [ 47 ] and, also, other compounds as the α-pinene, β-pinene, and 1,8-cineole compounds [ 48 ]. It has been noted a correlation between antioxidant components including 1,8-cineole, α-pinene, camphor, borneol, and transcaryophyllene and the antioxidant activity [ 48 ]. Various factors such as environmental factors, sampling techniques, extraction methods, plant organs and geographic origin could affect the amount of biomolecules responsible for the antioxidant capacity [ 49 ].…”

Section: Resultsmentioning

confidence: 99%

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Seasonal changes in rosemary species: A chemotaxonomic assessment of two varieties based on essential oil compounds, antioxidant and antibacterial activities

et al. 2022

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Rosemary (Rosmarinus officinalis L.) is a popular herb in cooking, traditional healing, and aromatherapy. This study was conducted to evaluate the effects of meteorological conditions plant growth stage and genetic factors on the yield, quantitative and qualitative composition, on the antioxidant and antimicrobial activities of rosemary essential oil from two Tunisian locations (El Fahs and Matmata) during two successive years. The composition of the essential oils obtained by hydrodistilation from rosemary plants were carried out annually using GC and GC/MS. Results showed the the main constituents were camphor (18.2–28.1%), 1,8-cineole (6.4–18.0%), α-pinene (9.7–13.5%), borneol (4.4–9.5%), and camphene (5.1–8.7%). The principal component and heatmapper analyses showed group segregation of the two studied varities based on major essential oil compounds. Additionally, in vitro antimicrobial and antioxidant activities showed that rosemary essential oils had an important ability in scavenging DPPH, as well as a higher bactericidal effect. The seasonal variation, growth stage and genetic pools seemed to be a factors of significant variation of the composition, antimicrobial and the antioxidant activities of the rosemary essential oils. These finding would be taken to use the chemotaxonomy tools to develop a program for Rosmary protection conservation and identification based on essential oil composition.

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“…Therefore, in our research, the synergistic effect of different concentration combinations of Lantana camara L essential oil can be explained to a large extent as the synergistic effect of its main components. However, other minor components of essential oils may also have potential and contribute to the observed antibacterial activity through synergistic interactions with the main compounds (Al Zuhairi et al, 2020;Mulyaningsih et al, 2010;Soulaimani et al, 2021).…”

Section: Antibacterial Activities Of Lantana Camara L Flowers Essential Oilmentioning

confidence: 99%

Analysis of Chemical Components and Antibacterial Activity in Essential Oil of Lantana Flowers (Lantana Camara L)

Sembiring¹,

Zuhra

2021

biomedika

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The purpose of this study was to evaluate the essential oil composition as well as antibacterial activities of essential oil of Lantana camara L flowers against four bacterial strains. Essential oil of Lantana camara L flowers was obtained by hydrodistillation method using Sthal and analyzed by GC-MS. The antibacterial activities of essential oil were tested by using disk diffusion method against four bacterial strains. Results showed 72 compounds for Lantana flowers essential oil, of which caryophyllene (10,87%), davanone (9.84%), a-humulene (7.59%), a-curcumene (3.35%), germacrene D (3.09%), calarene (2.42%), a-muurolene (2.27%), p-cymene (1.79%), 1,8 cineole (1.59%) , δ-cadinene (1.59%), a-copaene (1.12%), nerolidol B (1%) and ß-ocimene (0.54%) were detected as major components. Antibacterial activity assay of Lantana camara L flowers essential oil was examined against four bacterial strains including Gram (+and-) by using disk diffusion agar method. All the tested Gram (+and-) bacterial strains displayed slight to moderate antibacterial activity (7 – 10 mm) against all concentrations of essential oil. The essential oil of Lantana camara L flowers showed remarkable antibacterial activity with inhibition in concentrations of 10% and 20% against the phatogen bacterias Basillus subtilis (9.6 mm; 10.8 mm), Propionibacterium acnes ( 7.6 mm; 8.7 mm), Eschechia coli ( 8.4 mm ; 9.6 mm) and Pseudomonas aeruginosa ( 8.3 mm ; 9.3 mm) showed from zone of inhibition that was formed, zone of inhibition in concentration 20% was bigger than concentration 10%.

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Antioxidant, cytotoxic and antibacterial activity of Rosmarinus officinalis L. essential oil against bacteria isolated from urinary tract infection

Cited by 37 publications

References 30 publications

Antibacterial Effect of Lemongrass (Cymbopogon citratus) against the Aetiological Agents of Pitted Keratolyis

Antibacterial Effect of Lemongrass (Cymbopogon citratus) against the Aetiological Agents of Pitted Keratolyis

Seasonal changes in rosemary species: A chemotaxonomic assessment of two varieties based on essential oil compounds, antioxidant and antibacterial activities

Analysis of Chemical Components and Antibacterial Activity in Essential Oil of Lantana Flowers (Lantana Camara L)

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