Antioxidant properties of methanolic extracts from different parts of <i>Sclerocarya birrea</i>

Mariod, Abdalbasit Adam; Matthäus, Bertrand; Hussein, Ismail

doi:10.1111/j.1365-2621.2007.01543.x

Cited by 32 publications

(39 citation statements)

References 35 publications

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“…When mixed with other medicinal plants, the bark of S. birrea is employed to treat rheumatism and infectious diseases (Mojeremane and Tshwenyane 2004). The bark of S. birrea has also been reported to possess antioxidant activity (Mariod et al 2008). Previous studies revealed the anti-bacterial (Eloff 2001), anti-diabetic (Dimo et al 2007) and anti-convulsivant effect of the stem bark extracts of S. birrea (Ojewole 2007).…”

Section: Introductionmentioning

confidence: 97%

Acute and chronic anti-inflammatory properties of the stem bark aqueous and methanol extracts of Sclerocarya birrea (Anacardiaceae)

et al. 2009

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Sclerocarya birrea is used in folk medicine for the treatment of inflammatory disorders. The effect of the stem bark aqueous and methanol extracts of S. birrea (150 or 300 mg/kg) was evaluated on carrageenan-, histamine- or serotonin-induced paw oedema in rats. The methanol extract of S. birrea (300 mg/kg) being the most active, exhibited a maximum inhibition of 75.45 and 55.31% on carrageenan- and histamine-induced inflammation, respectively. When administered at 300 mg/kg, the methanol extract of S. birrea also exhibited 80.68% inhibition on the 10th day and 54.43% inhibition on the 21st day in formalin- or complete Freund's adjuvant (CFA)-induced paw oedema in rats. GSH level was significantly increased (75.14%), while MAD level was significantly decreased (31.22%) in the liver of CFA rats treated with S. birrea (300 mg/kg). The results suggest that the anti-inflammatory activity of the aqueous and methanol extracts of S. birrea is due to the inhibition of histamine and prostaglandin pathways and to its antioxidant activity.

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Section: Introductionmentioning

confidence: 97%

Acute and chronic anti-inflammatory properties of the stem bark aqueous and methanol extracts of Sclerocarya birrea (Anacardiaceae)

et al. 2009

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“…The DPPH (1,1-Diphenyl-2-picrylhydrazyl) method was used to evaluate the antioxidant activity of the extracts. The DPPH radical has been widely used to test the free radical scavenging ability of different plants [20]. The DPPH scavenging activities of the extracts are shown in Table 2.…”

Section: Resultsmentioning

confidence: 99%

Composition and content of total phenolics and flavonoids, and antioxidant activity of Trigonella isthmocarpa

et al. 2013

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KEYWORDSThe aqueous methanolic extracts obtained from aerial parts and seeds of T. isthmocarpa Boiss. & Bal. from Turkey were analyzed by reversed-phase HPLC for their phenolic acid and flavonoid composition. Total phenolic content was determined using the Folin-Ciocalteu assay, while total flavonoid content was measured spectrometrically with AlCl3 assay. Primary antioxidant activity in terms of free radical scavenging activities of both extracts was measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The highest total flavonoid and total phenolic content was determined in the extract of aerial parts (830.8 mg/100 g and 877.9 mg gallic acid equivalent/100 g, respectively). The extracts of aerial parts and seeds had the high antioxidant activity (87.2 % and 78.2%, respectively). Gallic acid, caffeic acid, luteolin, apigenin and kaempferol were detected as phenolic compounds in both extracts by HPLC methods. In addition, an isoflavone, formononetin was determined in the extract from aerial parts of the plant. The present results suggest that T. isthmocarpa have shown potential a source of natural antioxidants. HPLC Fabaceae Total phenol T. isthmocarpa Total flavonoid DPPH radical scavenging activity

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“…The powder Tetracera indica of 550 g was extracted with n-hexane solvent, ethyl acetate and ethanol respectively and after concentrated was obtained n-hexane extract 250 mg, ethyl acetate 3,50 g and ethanol extract 3.7 g. Each extract, has been done antioxidant activity test with varying concentration (Table 1). Mariod, Matthaus and Hussein, (2008) state that the value of antioxidant activity is determined based on the value of percentage inhibition, the higher the value of the inhibition, the higher the antioxidant activity. Table 1 showed that at the same concentration 1000 μg / mL, the ethanol extract showed the highest activity with inhibition 94.27% followed by ethyl acetate extract with inhibition 90.12%.…”

Section: Resultsmentioning

confidence: 99%

Flavon Compound from The Ethyl Acetate Extract of The Stem of Supit (Tetracera indica Merr.)

Muharni¹,

Elfita²,

Adillah

et al. 2018

Molekul

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Tetracera indica Merr. in Musi Banyuasin, is one of the traditional medicine used by the community for the treatment of kidney stone disease and gout, but this claim is not recorded in the treatment of kidney stones and gout in Indonesia. In this study, isolation of antioxidant compound from ethyl acetate extracts of supit (Tetracera indica) was done. The isolation was carried out through step gradient polarity extraction, and separated and purified by chromatography technique. The determination of the structure of the isolated compound was performed by spectroscopy method including UV, IR, and NMR 1D and 2D, and antoxidant activity was determined by DPPH method. An active antioxidant compound was isolated from ethyl acetate extract in form of yellow solid (15 mg). Based on spectroscopic analysis the isolated compound was 5,8-dihydroxy-7-methoxyflavone. The compound showed strong antioxidant activity (IC50 8.25 μg/mL) higher than standard ascorbic acid (IC50 11.3 μg/mL). This data concluded that efficacy of supit (Tetracera indica) for the treatment related to antioxidant activity (uric acid) is proven by the identification of one antioxidant compound of this plant.

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Antioxidant properties of methanolic extracts from different parts of Sclerocarya birrea

Cited by 32 publications

References 35 publications

Acute and chronic anti-inflammatory properties of the stem bark aqueous and methanol extracts of Sclerocarya birrea (Anacardiaceae)

Acute and chronic anti-inflammatory properties of the stem bark aqueous and methanol extracts of Sclerocarya birrea (Anacardiaceae)

Composition and content of total phenolics and flavonoids, and antioxidant activity of Trigonella isthmocarpa

Flavon Compound from The Ethyl Acetate Extract of The Stem of Supit (Tetracera indica Merr.)

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