Antioxidant properties, selected enzyme inhibition capacities, and a cosmetic cream formulation of Thai mango seed kernel extracts

Namngam, Chaianun; Pinsirodom, Praphan

doi:10.4314/tjpr.v16i1.3

Cited by 15 publications

(7 citation statements)

References 21 publications

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“…Antioxidant test and α-glucosidase inhibitory activity of seed kernel extract and fraction show a strong DPPH radical scavenging and α-glucosidase inhibitory capacity (Yang et al 2020). The 95% ethanol extracts from two different kinds of mango seed kernel, namely, Kaew and Choke-Anan, both had a good α-glucosidase inhibitory activity with IC50 values of 163:19 ± 2:33 and 113:51 ± 5:85 μg/ml (Namngam & Pinsirodom 2017). Other research showed that the methanol extract of mango seed kernel could significantly inhibit the activity of αglucosidase.…”

Section: Discussionmentioning

confidence: 99%

The potency of wild mango Mangifera magnifica as a new source of antidiabetic agents with concurrent antioxidant activity

Fitmawati

ROZA

EMRIZAL³

et al. 2022

Biodiversitas

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Abstract. Fitmawati, Roza RM, Emrizal, Juliantari E, Almurdani M. 2022. The potency of wild mango Mangifera magnifica as a new source of antidiabetic agents with concurrent antioxidant activity. Biodiversitas 23: 5159-5164. Diabetes mellitus has entered the top 10 causes of death, following a significant percentage increase of 70% since 2000. Researchers have been working on a new practical design of ?-glucosidase inhibitor from plant resources that can be used as a therapeutic agent for diabetes mellitus. By inhibiting ?-glucosidase, the digestion of carbohydrates slows down, which helps prevent hyperglycemia. In our preliminary study, M. magnifica is a neglected wild mango shown to have high levels of antioxidant activity. We conducted a study on the wild mango species M. magnifica as an ?-glucosidase enzyme inhibitor. Antioxidant activities were carried out by the method of radical reduction 1,1-diphenyl-2-picrylhydrazyl (DPPH). Total phenolic content (TPC) was calculated by the Folin-Ciocalteu method and total flavonoid content (TFC) was calculated by colorimetric method. The antidiabetic activity was carried out by in vitro ?-glucosidase biochemical test. The methanol extract and ethyl acetate fraction have high antioxidant activity and the strongest inhibitory ?-glucosidase activity. M. magnifica leaves are a new source of antihyperglycemic agents with concurrent antioxidant activity. The research results will provide new information to support conservation efforts whose status is already rare while maintaining and improving the quality of value and diversity.

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Section: Discussionmentioning

confidence: 99%

The potency of wild mango Mangifera magnifica as a new source of antidiabetic agents with concurrent antioxidant activity

Fitmawati

ROZA

EMRIZAL³

et al. 2022

Biodiversitas

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“…Polyphenols are the major group of plant antioxidants and are widely used in the cosmetic industry, for instance as ingredients of anti-ageing or whitening formulations as well as sunscreens. These substances are also used in pharmaceutical and food products and can be used as agents to help balance a healthy diet [15,16].…”

Section: Discussionmentioning

confidence: 99%

Antioxidant potential of Hippophae rhamnoides L. extracts obtained with green extraction technique

2018

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Summary Introduction: Antioxidants, isolated from different plant parts, are widely used due to their ability to prevent the development of so-called oxidative stress. Sea buckthorn (Hippophae rhamnoides L.) is one of the plants with expected antioxidant properties. Objective: The aim of the study was to evaluate the antioxidant activity of ethanolic, methanolic and acetonic extracts of H. rhamnoides leaves, ripe and unripe fruits obtained by ultrasound-assisted extraction. Methods: To estimate the antioxidant potential of the extracts the DPPH, FRAP, ABTS and Folin-Ciocalteu methods were applied. Moreover, the influence of the extrahent, as well as extraction time, on this activity was evaluated. Results: Sea buckthorn leaf extracts showed higher activity, contrary to the fruit extracts. Moreover, higher activity of ripe fruit extracts compared to unripe material extracts was found. To obtain the highest content of antioxidants in the extracts, ultrasound-assisted extraction for 60 min with methanol should be applied. Conclusions: The presented in vitro results could lead to the conclusion that H. rhamnoides seems to be a valuable source of antioxidants to be applied in various branches of industry.

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“…The equation based on the calibration curve was y = 56.818571x -0.066498 (R 2 = 0.9983), where x represents the absorbance and y was the mg quercetin. Formulation of topical creams containing Robinia pseudacacia L. flowers extract 3 samples of O/W cream with different compositions were prepared with ingredients the minimum amount of fatty base [14,18]. The creams were produced by melting (60°C) cetostearyl alcohol with stearic acid and isopropyl myristate and mixed in order to prepare the oil phase (Table I).…”

Section: Reagentsmentioning

confidence: 99%

Formulation and Antioxidant Investigation of Creams Containing Robiniae Pseudacaciae Flos L. Ethanolic Extract

Jurca¹

2021

FARMACIA

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Some vegetable products can be incorporated into skin care products in order to treat conditions such as skin dryness and can function as an antioxidant. Creams were formulated with Robiniae pseudacaciae flos extracts. This study was aimed to investigate the antioxidant activity of the ethanolic extracts and the obtained creams. The fractions of Robiniae pseudacaciae flos were found to be rich sources of polyphenols with marked antioxidant activity, evidenced by the DPPH method. The phenolic acids, identified by HPLC-RP with UV detection, were gallic acid, sinapic acid, caffeic acid and vanillic acid and the predominant flavonoids were quercetin, rutin and luteolin. The extract was previously dissolved in Transcutol and then mixed in the same oil/water (O/W) base containing Sucrose ester SP50, Tefose ® 63, Sedefos™ 75 as emulsifiers. The in vitro release of different compounds was evaluated by the Franz diffusion method. The creams containing Robiniae pseudacaciae flos extract exhibited large amounts of diffused substances. Antioxidant activity was determined by the DPPH (1,1-diphenyl-2-pycrylhydrazyl) method, according to the methodology described by Brand-Williams. RezumatUnele produse vegetale pot fi încorporate în produsele de îngrijire ale pielii pentru a trata condiții precum uscăciunea pielii și pot funcționa ca antioxidant. Cremele au fost formulate din extracte de flori de Robinia pseudoacacia L. În acest studiu am urmărit investigarea activității antioxidante a extractelor etanolice și a cremelor obținute. Fracțiile extrase din Robiniae pseudacaciae flos au fost surse bogate de polifenoli cu marcată activitate antioxidantă, evidențiată prin metoda DPPH. Acizii fenolici importanți, identificați prin HPLC-RP cu detecție UV, au fost acidul galic, acidul sinapic, acidul cafeic și acidul vanilic, iar flavonoidele predominante au fost quercetina, rutina și luteolina. Extractul a fost dizolvat anterior în Transcutol și apoi amestecat în aceeași bază cremă ulei în apă (U/A) conținând ester de zaharoză SP50, Tefose ® 63, Sedefos™ 75 ca emulgatori. Eliberarea in vitro a compușilor a fost evaluată prin metoda difuziei Franz. Cremele ce conțin extract de Robiniae pseudacaciae flos au prezentat mari cantități de substanțe difuzate. Activitatea antioxidantă a fost determinată prin metoda DPPH (1,1-difenil-2-picrilhidrazil), conform metodologiei descrise de Brand-Williams.

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Antioxidant properties, selected enzyme inhibition capacities, and a cosmetic cream formulation of Thai mango seed kernel extracts

Cited by 15 publications

References 21 publications

The potency of wild mango Mangifera magnifica as a new source of antidiabetic agents with concurrent antioxidant activity

The potency of wild mango Mangifera magnifica as a new source of antidiabetic agents with concurrent antioxidant activity

Antioxidant potential of Hippophae rhamnoides L. extracts obtained with green extraction technique

Formulation and Antioxidant Investigation of Creams Containing Robiniae Pseudacaciae Flos L. Ethanolic Extract

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