Antioxidant response mechanism of freshwater microalgae species to reactive oxygen species production: a mini review

Ugya, Adamu Yunusa; Imam, Tijjani Sabiu; Li, Anfeng; Ma, Jincai; Xia, Hua

doi:10.1080/02757540.2019.1688308

Cited by 75 publications

(33 citation statements)

References 136 publications

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“…In Schizochytrium sp., the expression levels of superoxide dismutase (SOD) and catalase (CAT) under high salinity stress were upregulated by 4.82 and 3.11-fold, respectively. Similar effects were also observed in other microalgal species, which indicated that enhancing the activity of antioxidant enzymes may be beneficial for lipid production (Ugya et al, 2020). Accordingly, when SOD was overexpressed in Schizochytrium sp., the ROS levels were greatly reduced and the PUFA titer was increased by 32.9% (Zhang et al, 2018).…”

Section: Theoretical Guidance For Rational Genetic Engineeringsupporting

confidence: 59%

Stresses as First-Line Tools for Enhancing Lipid and Carotenoid Production in Microalgae

Shi

Wang

Zhang

et al. 2020

Front. Bioeng. Biotechnol.

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Microalgae can produce high-value-added products such as lipids and carotenoids using light or sugars, and their biosynthesis mechanism can be triggered by various stress conditions. Under nutrient deprivation or environmental stresses, microalgal cells accumulate lipids as an energy-rich carbon storage battery and generate additional amounts of carotenoids to alleviate the oxidative damage induced by stress conditions. Though stressful conditions are unfavorable for biomass accumulation and can induce oxidative damage, stress-based strategies are widely used in this field due to their effectiveness and economy. For the overproduction of different target products, it is required and meaningful to deeply understand the effects and mechanisms of various stress conditions so as to provide guidance on choosing the appropriate stress conditions. Moreover, the underlying molecular mechanisms under stress conditions can be clarified by omics technologies, which exhibit enormous potential in guiding rational genetic engineering for improving lipid and carotenoid biosynthesis.

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Section: Theoretical Guidance For Rational Genetic Engineeringsupporting

confidence: 59%

Stresses as First-Line Tools for Enhancing Lipid and Carotenoid Production in Microalgae

Shi

Wang

Zhang

et al. 2020

Front. Bioeng. Biotechnol.

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“…Freshwater microalgae are microorganisms that are adapted to freshwater environment. They are unicellular and free living organism that ranges in size from 4 to 178 μm (Ugya et al 2020). Microalgae are able to utilize light, carbon dioxide and water for the process of photosynthesis to generate the energy needed for metabolic activities.…”

Section: Formation and Composition Of Natural Freshwater Microalgae Bmentioning

confidence: 99%

“…Since thousands of microalgae cell are involved in microalgae biofilm formation, these biofilm can biodegrade or biotransform pollutants resulting from mining activities by either degradation or accumulation (Wang et al 2019). The ability of microalgae biofilm to cause the degradation of pollutants present in mining wastewater could be as a result of the enzyme activities produced by the individual microalgae cell present in the biofilm (Baghour 2019) or due to the increased level of reactive oxygen species (ROS) produced as a result of the high amount of microalgae cells forming the biofilm (Ugya et al 2020).…”

Section: The Role Of Natural Freshwater Microalgae Biofilm In Pollutamentioning

confidence: 99%

“…Many studies have shown that freshwater microalgae biofilm is able to produce reactive oxygen species (ROS) which is capable of oxidizing persistent organic compound, thereby bringing about the degradation of these compounds into CO 2 , CO 3 2− and H 2 O with the products being utilized by the freshwater microalgae for biomass production (Shi and Xu 2019). Studies by Ugya et al (2020) show that freshwater microalgae biofilm is able to produce ROS of high concentration, which is capable of degrading persistent organic compounds such as trichlorobenzene, tetrachlorobenzene, alkyl halides, and some heavy organic compounds such as PCBs. These studies also reveal that the ROS produced by freshwater microalgae is capable of degrading sulphur containing pollutants because of the potentiality of ROS to desulfurize thiocarbonyl compounds such as thiouracils, thioamides and thioureas to carbonyl compounds (Shi and Xu 2019).…”

Section: The Role Of Natural Freshwater Microalgae Biofilm In Pollutamentioning

confidence: 99%

“…The autotrophic organisms present in natural biofilms consist of microalgae and cyanobacteria, whereas heterotrophic organisms include bacteria, fungi and protist (Xuemei et al 2010). These organisms form a natural biofilm and accumulate on the surface of an artificial or natural substrate which are surrounded by EPS (Ugya et al 2020). The EPS of natural biofilm is the reason why biofilm is able to resist environmental stress, thus causing the degradation of pollutants in aquatic environment (Han et al 2017).…”

Section: Introductionmentioning

confidence: 99%

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Natural freshwater microalgae biofilm as a tool for the clean-up of water resulting from mining activities

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Microalgae‐Derived Health Supplements to Therapeutic Shifts: Redox‐Based Study Opportunities with AIE‐Based Technologies

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Zhu

Qin

et al. 2021

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Reactive oxygen species (ROS) are highly reactive molecules, serve the normal signaling in different cell types. Targeting ROS as the chemical signals, different stress based strategies have been developed to synthesis different anti‐inflammatory molecules in microalgae. These molecules could be utilized as health supplements in human. To provoke the ROS‐mediated defence systems, their connotation with the associated conditions must be well understood, therefore, proper tools for studying ROS in natural state are essential. The in vivo detection of ROS with phosphorescent probes offers promising opportunities to study these molecules in a non‐invasive manner. Most of the common problems in the traditional fluorescent probes are lower photostability, excitation intensity, slow responsiveness, and the microenvironment that challenge their performance. Some ROS‐specific aggregationinduced emission luminogens (AIEgens) with pronounced spatial and temporal resolution have recently demonstrated high selectivity, rapid responsiveness, and efficacies to resolve the aggregation‐caused quenching issues. The nanocomposites of some AIE‐photosensitizers can also improve the ROS‐mediated photodynamic therapy. These AIEgens could be used to induce bioactive components in microalgae through altering the ROS signaling, therefore are more auspicious for biomedical research. This study reviews the prospects of AIEgen‐based technologies to understand the ROS mediated bio‐physiological processes in microalgae for better healthcare benefits.

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Antioxidant response mechanism of freshwater microalgae species to reactive oxygen species production: a mini review

Cited by 75 publications

References 136 publications

Stresses as First-Line Tools for Enhancing Lipid and Carotenoid Production in Microalgae

Stresses as First-Line Tools for Enhancing Lipid and Carotenoid Production in Microalgae

Natural freshwater microalgae biofilm as a tool for the clean-up of water resulting from mining activities

Microalgae‐Derived Health Supplements to Therapeutic Shifts: Redox‐Based Study Opportunities with AIE‐Based Technologies

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