Antioxidantes dietéticos: controvérsias e perspectivas

Cerqueira, Fernanda M.; Medeiros, Marisa H. G.; Augusto, Ohára

doi:10.1590/s0100-40422007000200036

Cited by 98 publications

(90 citation statements)

References 56 publications

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“…Among the natural antioxidants, the vitamin E, ascorbic acid, carotenoids and especially phenolic compounds are the most important antioxidants for the human diet (Cerqueira et al, 2007). These promote a protective action against the oxidative processes in the body and are important in the interception of free radicals (Bianchi & Antunes, 1999;Duarte-Almeida et al, 2006).…”

Section: Resultsmentioning

confidence: 99%

Characterization of bioactive compounds, antioxidant activity and minerals in landraces of pumpkin (Cucurbita moschata) cultivated in Southern Brazil

et al. 2016

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The objective of this work was to evaluate the genetic variability for the synthesis of bioactive compounds and minerals in pumpkin (Cucurbita moschata) landraces. Total phenolic compounds, carotenoids, antioxidant activity and minerals were evaluated in 10 accessions of Cucurbita moschata landraces from the Genebank of Embrapa Temperate Agriculture (Pelotas -RS, Brazil). Twenty plants of each accession were cultivated in the field during the spring/summer of 2013/2014. After harvesting of mature fruits, the seeds were discarded and opposite longitudinal portions of the pulp were manually prepared for analysis of the bioactive compounds. For the determination of minerals, pumpkin samples were frozen in plastic bags, and after freeze-dried and milled. All analysis were performed in triplicate. The data obtained showed high genetic variability for the synthesis of phenolic compounds, carotenoids, antioxidant activity and minerals. The accessions C52, C81, C267 e C389 showed high levels of antioxidants and minerals, being recommended for use in pumpkin breeding programs. The accessions C52 and C389 are promising, especially because they present the highest levels of total carotenoids.Keywords: pumpkin; cucurbitaceae; ex situ conservation; genetic resources; characterization.Practical Application: Pumpkins (Cucurbita moschata) are important to the human diet due to its functional properties and benefits for the human health. Identify genetic variability for the synthesis of bioactive compounds and minerals can be useful for breeding programs, to develop cultivars with improved benefits to the consumers.

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Section: Resultsmentioning

confidence: 99%

Characterization of bioactive compounds, antioxidant activity and minerals in landraces of pumpkin (Cucurbita moschata) cultivated in Southern Brazil

et al. 2016

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“…Although the body possesses effective endogenous antioxidant defenses to fight excess free radicals, such as enzymes superoxide dismutase, peroxidase, catalase, and glutathione peroxidase 3 , they are believed to be not infallible. Therefore, there is a constant formation of free radicals 4 . Thus, antioxidants obtained through a diet are indispensable for proper defense against oxidation, and therefore play an important role in maintaining health.…”

Section: Introductionmentioning

confidence: 99%

Avaliação da ingestão de nutrientes antioxidantes pela população brasileira e sua relação com o estado nutricional

Tureck

Locateli

Corrêa

et al. 2017

Rev. bras. epidemiol.

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Introduction:The study of dietary antioxidants has gained prominence owing to the elucidation of the deleterious effects of oxidative stress to the human body. Objective: To evaluate the Brazilian population's intake of antioxidant nutrients and their association with the nutritional status. Methods: A cross-sectional study was carried out including secondary data on food consumption of 33,459 individuals from both sexes, aged 10 years or older, from all Brazilian regions based on microdata of the "2008-2009 Household Budget Survey, Brazilian Dairy Survey." The content of vitamins E, A, and C; zinc; manganese; copper; and selenium from 188 food items, divided into 12 groups, according to the habitual consumption form was analyzed. The means of antioxidant nutrient intake according to the nutritional status were compared using Bonferroni's t-test. Results: Higher percentages of insufficient intake of vitamins than antioxidant minerals were seen. A significant difference in the intake of vitamin E as to the nutritional status was noticed, wherein the intake in overweight individuals was lower than in those with proper weight. Participants with low weight presented lower intake of almost all antioxidant minerals, except for copper, in which the intake of participants with low weight was equal to those with normal weight. Conclusion: High percentages of insufficient intake of antioxidant nutrients were observed in the studied population, especially vitamins. It was also found that the intake of antioxidant nutrients varied based on nutritional status, gender, and life stage.

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“…In addition to the capture of free radicals, cell culture studies demonstrate that vitamin C can alter the expression of genes involved in the inflammatory response, apoptosis, and cell differentiation [27].…”

Section: Discussionmentioning

confidence: 99%

Ascorbic Acid and Performance: A Review

Quadros¹

2016

Vitam Miner

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Purpose: Review of the evidence which supports the consumption of vitamin C for sportsmen and athletes aiming improvement performance. Data synthesis: Vitamin C is an essential micronutrient with several important biological functions. In addition to being considered a potent antioxidant that eliminates reactive oxygen and nitrogen species. Among other functions, vitamin C reduces the symptoms of colds and flu, accelerating the recovery process and has an anti-catabolic effect. This effect has fundamental importance for the physically active. Considering that vitamin C participates as a cofactor in carnitine biosynthesis, steroid hormones and neurotransmitters, it has been established the idea that the need for this nutrient would increase for people engaged in strenuous exercise or frequent stress. Because of this, this paper aims to investigate the role of this micronutrient in performance. Material and methods:We searched the published scientific literature for randomized controlled trials of adult human subjects reporting vitamin C intake and training, besides animal models and literature review about the topic. Twenty-eight papers since 2000 were identified by searches of PubMed, with the search terms "ascorbic acid", "bioavailability", "oxidative stress", "performance", "free radicals" "supplementation", "toxicity" and "vitamin C", ensuring recent knowledge about ascorbic acid. Conclusions:The importance of vitamin C in the diet is indisputable, but more research is needed to clarify whether supplementation of this micronutrient actually leads to performance optimization.

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Antioxidantes dietéticos: controvérsias e perspectivas

Cited by 98 publications

References 56 publications

Characterization of bioactive compounds, antioxidant activity and minerals in landraces of pumpkin (Cucurbita moschata) cultivated in Southern Brazil

Characterization of bioactive compounds, antioxidant activity and minerals in landraces of pumpkin (Cucurbita moschata) cultivated in Southern Brazil

Avaliação da ingestão de nutrientes antioxidantes pela população brasileira e sua relação com o estado nutricional

Ascorbic Acid and Performance: A Review

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