Antioxidants and Their Role in Preventing Diseases: A Review

Hassan, Ekhlas Abdallah; Al-Zuhairi, Wafaa Sh.; Ibrahim, Wijdan Amer

doi:10.34198/ejcs.7222.165182

Cited by 4 publications

(2 citation statements)

References 46 publications

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“…In comparison, the other three are tetramers (four units) in structure (four subunits). SOD1 and SOD3 include copper and zinc, while SOD2 contains manganese in the reactive core [48,49].…”

Section: Superoxide Dismutasementioning

confidence: 99%

Involvement of Antioxidant in the Prevention of Cellular Damage

Ogunro¹,

Fakayode²,

Batiha³

2023

Biochemistry

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Oxidative stress occurs when the body’s enzymatic or non-enzymatic antioxidants are outweighed by endogenous or exogenous free radicals. Oxidative radicals, reactive oxygen species, and other biomolecule-damaging free radicals can be generated during normal cellular metabolism and react with proteins, lipids, and DNA. In the domains of biology and medicine, free radicals have become increasingly important. They can accumulate in a variety of ways, both endogenously and exogenously. Mitochondria are the primary source of cell-level endogenous reactive oxygen species. In several chronic and degenerative disorders, this results in tissue destruction. In addition to being produced endogenously, antioxidants can also be delivered exogenously to the biological system, most frequently through nutrition. Antioxidants are generally used to counteract the effects of free radicals produced by metabolic processes. In this chapter, the crucial function of reactive oxygen species in human health, as well as exploring the functioning of antioxidative defense systems in reducing toxicity caused by excess reactive oxygen species were discussed.

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“…In comparison, the other three are tetramers (four units) in structure (four subunits). SOD1 and SOD3 include copper and zinc, while SOD2 contains manganese in the reactive core [48,49].…”

Section: Superoxide Dismutasementioning

confidence: 99%

Involvement of Antioxidant in the Prevention of Cellular Damage

Ogunro¹,

Fakayode²,

Batiha³

2023

Biochemistry

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“…Spinach is also known for its anti-inflammatory, antitumoral, anti-obesity and lipid-lowering effects. Consuming more antioxidant-rich fruits and vegetables, like spinach, may halt the deterioration of antioxidant defense mechanisms that occur with ageing (Hassan et al, 2022). Spinach crops must be improved in quality 2 and yield by finding new approaches.…”

Section: Introduction Introduction Introduction Introductionmentioning

confidence: 99%

Improving quality parameters of spinach by adjusting light spectra under moderate water deprivation conditions

ZARGAR,

BASAL,

VERES

2023

Not Bot Horti Agrobo

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Spinach (Spinacia oleracea L.) is a highly valuable leafy vegetable, abundant in vitamins, minerals, and antioxidants, offering various health benefits such as enhancing cardiovascular health, reducing inflammation, and aiding digestion. Consequently, it is crucial to effectively cultivate and maintain spinach's quality. Light plays a pivotal role in the growth and development of plants, including spinach, where different light qualities can influence its morpho-physiological traits and overall quality. To explore this, an experiment was conducted, using three distinct LED lighting sets for spinach cultivation. Light 1 emphasized blue light, Light 2 served as the standard white light control, and Light 3 focused more on red light with occasional brief UV-C flashes. Additionally, mild water deprivation was induced using 2.5% polyethylene glycol (PEG). The results revealed that using a high red-to-blue light ratio with intermittent UV-C radiation significantly reduced various growth parameters of spinach, such as root length, shoot length, root volume, fresh and dry root and shoot weight, as well as total and relative chlorophyll contents, when compared to the control group. Furthermore, water deprivation had a negative impact on spinach's growth, affecting shoot and root length, and fresh and dry weight in all light qualities, proving to be fatal under Light 3 conditions. Therefore, it is essential to carefully select appropriate light qualities throughout the plant's life cycle to enhance the quality of spinach, especially when mild water deprivation is involved. Opting for a higher blue-to-red light ratio was found to be somewhat beneficial in improving the overall quality of spinach.

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C(60) fullerene effect on the functional activity of rat gastrocnemius muscle during its regeneration after the open injury

Nozdrenko,,

Gonchar,,

Nurishchenko,

et al. 2024

Ukr.Biochem.J.

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Open injuries are one of the most common skeletal muscle traumas. The study aimed to estimate the effect of the oral administration of C60 fullerene aqueous solution (C60FAS) daily at a dose of 1 mg/kg on the restoration of rat skeletal muscle functional activity on the 5th, 10th and 15th day after the open trauma. Male Wistar rats were randomly divided into three groups of 12 animals in each: control, with muscle injury and with muscle injury+C60FAS. The isolated gastrocnemius muscle was subjected to open injury by transverse dissection with a depth of 1 mm. Stimulation of muscle efferents was carried out by electrical impulses generated using a strain gauge generator. The content of C-reactive protein, creatinine, lactate, reduced glutathione and the activity of catalase and superoxide dismutase in the rat blood were determined. According to the data obtained, application of C60FAS promotes the restoration of the functional activity of injured muscle, which was confirmed by a significant increase in gastrocnemius muscle force impulse, attenuation of the inflammatory and development of fatigue and normalization of pro- and antioxidant balance in the process of regeneration. Keywords: C60 fullerene, gastrocnemius muscle, lactate, muscle force impulse, open injury, pro-antioxidant balance, protein C

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Antioxidants and Their Role in Preventing Diseases: A Review

Cited by 4 publications

References 46 publications

Involvement of Antioxidant in the Prevention of Cellular Damage

Involvement of Antioxidant in the Prevention of Cellular Damage

Improving quality parameters of spinach by adjusting light spectra under moderate water deprivation conditions

C(60) fullerene effect on the functional activity of rat gastrocnemius muscle during its regeneration after the open injury

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