Antioxidants Do Not Prevent Postexercise Peroxidation and May Delay Muscle Recovery

Teixeira, Vítor Hugo; Valente, Hugo; Casal, Susana; Marques, António; Moreira, Pedro

doi:10.1249/mss.0b013e31819fe8e3

Cited by 90 publications

(102 citation statements)

References 32 publications

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“…Plasma levels of TAS and CK were analyzed using commercially available methods (TAS: Randox NX2332 kit; Randox, Crumlin, UK; CK: Roche Products, UK) on a Cobas Mira Plus analyzer (Roche Diagnostic Systems) and an automated system (Cobas Mira Plus; Roche Diagnostic Systems), respectively (Teixeira et al 2009). The coefficient of variation (CV%) for TAS intra-assay and inter-assay were 3.4% and 3%, respectively; in addition, the CV% for CK intraassay and inter-assay were 3.5% and 3.1%, respectively.…”

Section: Analyses Of Biochemical Biomarkers For Oxidative Stress and mentioning

confidence: 99%

Green tea extract supplementation does not hamper endurance-training adaptation but improves antioxidant capacity in sedentary men

Kuo

Lin

Bernard

et al. 2015

Appl. Physiol. Nutr. Metab.

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Abstract:The purpose of this study was to investigate the effect of green tea extract (GTE) supplementation combined with endurance training on endurance capacity and performance in sedentary men. Forty untrained men (age: 20 ± 1 years) participated in this study. Subjects were assigned to 1 of 4 treatments: (i) placebo-control (CTRL), (ii) GTE, (iii) endurance training (Ex), and (iv) endurance training with GTE (ExGTE). During the 4-week intervention, exercise training was prescribed as 75% oxygen uptake reserve for three 20-min sessions per week, and either GTE (250 mg/day) or placebo was provided. Endurance capacity, malondialdehyde (MDA), total antioxidant status (TAS), and creatine kinase (CK) were examined. Ex and ExGTE but not GTE improved exhaustive-run time (Ex: +8.2%, p = 0.031; ExGTE: +14.3%, p < 0.001); in addition, Ex and ExGTE significantly increased maximal oxygen uptake by ϳ14% (p = 0.041) and ϳ17% (p = 0.017) above the values of the CTRL group, respectively. Both Ex and ExGTE significantly decreased the increase of CK by ϳ11%-32% below that of CTRL following an exhaustive run (Ex: p = 0.007; ExGTE: p = 0.001). Moreover, TAS levels increased by ϳ11% in ExGTE after training (p = 0.040), and GTE, Ex, and ExGTE markedly attenuated exercise-induced MDA production (p = 0.01, p = 0.005, p = 0.011, respectively). In conclusion, this investigation demonstrated that daily ingestion of GTE during endurance training does not impair improvements in endurance capacity. Moreover, endurance training combined with GTE not only increases antioxidant capacity without attenuating endurance training adaptations, but also further attenuates acute exercise-induced CK release.Key words: V O 2max , malondialdehyde (MDA), creatine kinase (CK), oxidative stress, catechins.Résumé : Cette étude se propose d'examiner l'effet de la supplémentation en extrait de thé vert (« GTE ») combinée à l'entraînement en endurance sur la capacité d'endurance et la performance chez des hommes sédentaires. Quarante hommes non entraînés (âge de 20 ± 1 ans) participent à cette étude. Les sujets sont assignés à l'un des quatre traitements : (i) placebocontrôle (« CTRL »), (ii) GTE, (iii) entraînement en endurance (Ex) et (iv) entraînement en endurance plus GTE (ExGTE). Durant les quatre semaines de l'intervention, l'entraînement physique consiste en trois séances de 20 min à une intensité sollicitant 75 % du consommation d'oxygène de réserve dans la condition de GTE (250 mg/jour) ou de placebo. On évalue la capacité d'endurance, le taux de malonaldéhyde (« MDA »), le statut antioxydant total (« TAS ») et la créatine kinase (« CK »). Ex et ExGTE, mais pas GTE suscitent une amélioration du temps de course jusqu'à épuisement (Ex: +8,2 %, p = 0,031; ExGTE: +14,3 %, p < 0,001); de plus, Ex et ExGTE suscitent une augmentation significative du consommation maximale d'oxygène de ϳ14 % (p = 0,041) et de ϳ17 % (p = 0,017) respectivement par rapport au groupe CTRL. EX et ExGTE suscitent une baisse significative de l'augmentation de CK de ϳ11-32 % par rap...

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Section: Analyses Of Biochemical Biomarkers For Oxidative Stress and mentioning

confidence: 99%

Green tea extract supplementation does not hamper endurance-training adaptation but improves antioxidant capacity in sedentary men

Kuo

Lin

Bernard

et al. 2015

Appl. Physiol. Nutr. Metab.

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“…After high-intensity exercise that results in high muscle and blood concentrations of lactate, some recovery of glycogen stores in the absence of additional carbohydrate feeding is possible, but sustained muscle glycogen synthesis after exercise is dependent on provision of a dietary source of carbohydrate (Burke et al, 2004). Provided that total energy intake is adequate (Tarnopolsky et al, 2001), increasing carbohydrate intake promotes increased muscle glycogen storage until an upper limit for glycogen synthesis is reached (Burke et al, 2004). The most recent guidelines for postexercise glycogen storage recognize a scaling of requirements according to the fuel cost of training or competition and the athlete's body size .…”

Section: Refuelingmentioning

confidence: 99%

Nutrition for Recovery in Aquatic Sports

Burke¹,

Mujika²

2014

International Journal of Sport Nutrition and Exercise Metabolism

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Postexercise recovery is an important topic among aquatic athletes and involves interest in the quality, quantity, and timing of intake of food and fluids after workouts or competitive events to optimize processes such as refueling, rehydration, repair, and adaptation. Recovery processes that help to minimize the risk of illness and injury are also important but are less well documented. Recovery between workouts or competitive events may have two separate goals: (a) restoration of body losses and changes caused by the first session to restore performance for the next and (b) maximization of the adaptive responses to the stress provided by the session to gradually make the body become better at the features of exercise that are important for performance. In some cases, effective recovery occurs only when nutrients are supplied, and an early supply of nutrients may also be valuable in situations in which the period immediately after exercise provides an enhanced stimulus for recovery. This review summarizes contemporary knowledge of nutritional strategies to promote glycogen resynthesis, restoration of fluid balance, and protein synthesis after different types of exercise stimuli. It notes that some scenarios benefit from a proactive approach to recovery eating, whereas others may not need such attention. In fact, in some situations it may actually be beneficial to withhold nutritional support immediately after exercise. Each athlete should use a cost-benefit analysis of the approaches to recovery after different types of workouts or competitive events and then periodize different recovery strategies into their training or competition programs.

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“…The lack of effects appears to be particularly evident in highly trained individuals whose adaptation to increased exposure to oxidation is normally able to promote a secondary increase of the endogenous antioxidant defenses that reduce the risk of oxidative damage [58,59] Therefore even following extreme exercise paradigms, unlike short periods of modest exercise [60], indications of oxidative damage may lack in well trained athletes [61]. Importantly in these conditions exposure to antioxidants may hinder the beneficial cell adaptations to exercise thereby promoting muscle damage instead of recovering from it [55, [62][63][64]. In fact there are concerns about possible adverse effects of megadose supplementation, as several of these nutrients have been shown to increase markers of exercise-induced oxidative stress thus serving as prooxidants instead of antioxidant nutrients.…”

Section: Antioxidant/vitaminesmentioning

confidence: 99%

Nutritional Interventions as Potential Strategy to Minimize Exercise-Induced Muscle Injuries in Sports

D’Antona¹

2013

Muscle Injuries in Sport Medicine

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Antioxidants Do Not Prevent Postexercise Peroxidation and May Delay Muscle Recovery

Abstract: AOX supplementation does not offer protection against exercise-induced lipid peroxidation and inflammation and may hinder the recovery of muscle damage.

Cited by 90 publications

References 32 publications

Green tea extract supplementation does not hamper endurance-training adaptation but improves antioxidant capacity in sedentary men

Green tea extract supplementation does not hamper endurance-training adaptation but improves antioxidant capacity in sedentary men

Nutrition for Recovery in Aquatic Sports

Nutritional Interventions as Potential Strategy to Minimize Exercise-Induced Muscle Injuries in Sports

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