Antioxidative effect of the constituents of rosemary (Rosmarinus officinalis L.) and their derivatives.

Inatani, Reiko; Nakatani, Nobuji; Fuwa, Hidetsugu

doi:10.1271/bbb1961.47.521

Cited by 148 publications

(104 citation statements)

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“…In this assay, hydroperoxides produced from linoleic acid added to the reaction mixture, which has oxidized in air during the experimental period, were indirectly measured. Ferrous chloride and thiocyanate react with each other to produce ferrous thiocyanate (red colour) by means of hydroperoxides [51].…”

Section: Discussionmentioning

confidence: 99%

In vitroantioxidant activity of silymarin

Köksal

Gülçın

Beyza

et al. 2009

Journal of Enzyme Inhibition and Medicinal Chemistry

203

100

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Silymarin, a known standardized extract obtained from seeds of Silybum marianum is widely used in treatment of several diseases of varying origin. In the present paper, we clarified the antioxidant activity of silymarin by employing various in vitro antioxidant assay such as 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH·) scavenging, 2,2 0 -azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, total antioxidant activity determination by ferric thiocyanate, total reducing ability determination by Fe 3þ 2 Fe 2þ transformation method and Cuprac assay, superoxide anion radical scavenging by riboflavin/methionine/illuminate system, hydrogen peroxide scavenging and ferrous ions (Fe 2þ ) chelating activities. Silymarin inhibited 82.7% lipid peroxidation of linoleic acid emulsion at 30 mg/mL concentration; butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), a-tocopherol and trolox indicated inhibition of 83.3, 82.1, 68.1 and 81.3% on peroxidation of linoleic acid emulsion at the same concentration, respectively. In addition, silymarin had an effective DPPH· scavenging, ABTS zþ scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, ferric ions (Fe 3þ ) reducing power by Fe 3þ 2 Fe 2þ transformation, cupric ions (Cu 2þ ) reducing ability by Cuprac method, and ferrous ions (Fe 2þ ) chelating activities. Also, BHA, BHT, a-tocopherol and trolox, were used as the reference antioxidant and radical scavenger compounds. Moreover, this study, which clarifies antioxidant mechanism of silymarin, brings new information on the antioxidant properties of silymarin. According to the present study, silymarin had effective in vitro antioxidant and radical scavenging activity. It could be used in the pharmacological and food industry because of its antioxidant properties.

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Section: Discussionmentioning

confidence: 99%

In vitroantioxidant activity of silymarin

Köksal

Gülçın

Beyza

et al. 2009

Journal of Enzyme Inhibition and Medicinal Chemistry

203

100

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“…Piperine [1] showed no activity. All phenolic amides [2][3][4][5][6] showed significant activity, more effective than cx-tocopherol at the same concentration (0.01%). The activity of compound [5] was as high as that of synthetic antioxidants, BHA and BHT, at the same level.…”

Section: Antioxidative Activitymentioning

confidence: 99%

“…Antioxidative activity of each sample to protect linoleic acid was measured by the ferric thiocyanate method and thiobarbituric acid method (TBA) (2). The sample solution, prepared according to our method at a concentration of 0.01% or 0.02%, was kept in a dark oven at 40°C.…”

Section: Antioxidative Assaymentioning

confidence: 99%

Chemical constituents of peppers (Piper spp.) and application to food preservation: naturally occurring antioxidative compounds.

Nakatani¹,

Inatani²,

Ohta³

et al. 1986

Environ Health Perspect

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In a structure analysis of the compounds of the genus Piper (Family Piperaceae), we identified five phenolic amides from Piper nigrum, seven compounds from P. retrofractum, and two compounds from P. baccatum. All the phenolic amides possess significant antioxidant activities that are more effective than the naturally occurring antioxidant, alpha-tocopherol. One amide, feruperine, has antioxidant activity as high as the synthetic antioxidants, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). Naturally occurring antioxidants, therefore, may surpass BHA and BHT in their ability to inactivate mutagens in food.

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“…The MESR had triterpenes, flavonoids, tannins and carbohydrates, while MEDR provided the presence of triterpenes, tannins, flavonoids and carbohydrates (Table 3). Chromatographic separation of MEBA revealed the identification of , which latter forms a complex with SCNG that has a maximum absorbance at 500 nm (Inatani et al, 1983). In the presence of antioxidants, Fe 3+ ion formation becomes more difficult and therefore, the absorbance of SCNG complex is expected to be lower.…”

Section: Resultsmentioning

confidence: 99%

Comparative Study of Antioxidant Activity from some Egyptian Plants and Phytochemical Composition

Rashed¹,

Güder²

2015

Research J. of Medicinal Plant

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This study evaluated antioxidant potential of methanol extract of three Egyptian plants, Bauhinia alba (MEBA), Solanum rantonnetii (MESR) and Derris rubosta (MEDR) and also investigated their main phytoconstituents. The extracts leaves of the of the three plants were subjected to antioxidant assays, namely total antioxidant activity, reducing power, metal chelating, hydrogen peroxide, radical scavenging activities were studied according to in vitro methods at the different concentrations (25-100 µg mLG 1 ) and each extract was subjected to phytochemical analysis. The results proved that MEBA had strong inhibition (%) of peroxide levels 84.88±0.83 when compared with the standards, such as BHA, TRO and RUT which have 82.03±1.04, 80.56±0.60, 78.50±0.41, respectively. The MEBA demonstrated effective reducing power, hydrogen peroxide scavenging activity and metal chelating activities. On the other hand, no correlation was found between antioxidant activity and total phenol and flavonoid contents. Chromatographic separation of MEBA proved the identification of betulin, betulinic acid, ursolic acid, kaempferol, isorhamnetin, kaempferol 3-O-α-rhamnoside, isorhamnetin 7-O-α-rhamnoside and rutin. Hence, it was concluded that Bauhinia alba has antioxidant activity and can be further employed for medicinal applications.

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Antioxidative effect of the constituents of rosemary (Rosmarinus officinalis L.) and their derivatives.

Cited by 148 publications

References 0 publications

In vitroantioxidant activity of silymarin

In vitroantioxidant activity of silymarin

Chemical constituents of peppers (Piper spp.) and application to food preservation: naturally occurring antioxidative compounds.

Comparative Study of Antioxidant Activity from some Egyptian Plants and Phytochemical Composition

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