Antioxidative Peptides: Trends and Perspectives for Future Research

Abstract

In recent years, much attention has been given to dietary antioxidants, especially polyphenols. Several peptides derived from protein molecules have also been found to show antioxidant capacity along with other biological properties and thus there is an increasing interest in these compounds as health promoters. This review summarizes and discusses the main sources of antioxidative peptides with focus on food-derived peptides (animal, plant and marine sources), methods of preparation, antioxidant capacity evaluation as well as their proposed mechanisms of action. A discussion of the potential health effects and comments on the different applications for these antioxidants and their potential research interest are also subject of this review.

Generation of bioactive peptide hydrolysates from cattle plasma using plant and fungal proteases

“…This enables access to scavenge free radicals generated at the lipid phase (Freitas, Andrade, Silva, Rocha-Santos, Duarte, & Gomes, 2013;Ko et al, 2012;Ranathunga, Rajapakse, & Kim, 2006). Some of the peptides obtained through the hydrolysis of cattle plasma in this study appear to be unique compared to other reported antioxidant peptides.…”

Chemical Characterization, Antioxidant and Enzymatic Activity of Brines from Scandinavian Marinated Herring Products

“…In a previously published review by Freitas et al [43] these same amino acids were, together with the sulfur containing amino acids, reported to provide antioxidant activity. All of the brines tested here contained these amino acids (Table 4).…”

“…The three tested antioxidant activities can, according to different mechanisms, prevent oxidation in food. Nevertheless, the classic in vitro tests for measuring antioxidant activity may not reveal the exact antioxidant potential of the brines in foods, and thus, tests in different food matrices should also be conducted [43]. Based on Figures 2-4, the most promising brines for further testing the antioxidant activity is the two blood-rich brines, TSa and TSp, together with SC and future studies will reveal whether the activity is solely in the protein-free fraction or if protein/peptides contribute to their antioxidant activity.…”

Introduction to the Analysis of Bioactive Compounds in Marine Samples

“…Hu et al [37] found diterpene erythrazole B in active extracts of Erythrobacter sp., and this compound showed citotoxic properties against non-small-cell lung cancer (NSCLC) cell lines. Tsukada et al [44] isolated the decarboxyhydroxycitrinone, a terpene, from the marine fungus Arthrinium sacchari, with antiangiogenic activity.…”