Antiplatelet therapy for coronary artery disease in 2023: current status and future prospects

Percutaneous coronary intervention with implantation of second-generation drug-eluting stents (DES) has emerged as a mainstay for the treatment of obstructive coronary artery disease given its beneficial impact on clinical outcomes in these patients. Everolimus-eluting stents (EES) are one of the most frequently implanted second-generation DES; their use for the treatment of a wide range of patients including those with complex coronary lesions is supported by compelling evidence. Although newer stent platforms such as biodegradable polymer DES may lower local vessel inflammation, their efficacy and safety have not yet surpassed that of Xience stents. This article summarizes the properties of the Xience family of EES and the evidence supporting their use across diverse patient demographics and coronary lesion morphologies.

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The Neurophysiological Effects of Virtual Reality Application and Perspectives of Using for Multitasking Training in Cardiac Surgery Patients: Pilot Study

Tarasova,

Trubnikova,

Kukhareva

et al. 2024

Applied Sciences

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Background: The use of virtual reality (VR) has great potential for medical research and practice, which can help expand rehabilitation activities. This study aimed to evaluate the acceptability and feasibility of the original protocol VR multitasking cognitive training (CT) in both a healthy group and cardiac surgery patients. Methods: A specialized hardware and software complex was developed and tested on both a group of 25 practically healthy individuals, mean age 22.9 years (SD 2.57), and 25 cardiac surgery patients, mean age 62.2 years (SD 7.35). The participants were instructed to complete one session of multitasking CT within the VR complex. Psychometric testing and EEG studies were conducted. Results: All participants were highly accepting of the intended future use, attitude, and pleasure of the training. The healthy subjects demonstrated a statistically significant improvement in attention and spatial skills after VR (p ˂ 0.05). The EEG data revealed a significant increase in alpha power compared to pre-experiment levels (p ˂ 0.0001). The theta/alpha ratio significantly decreased after the VR multitasking CT as compared to the baseline (p ˂ 0.0001). Conclusions: The data obtained indicate that the original training protocol for multitasking CT using VR is acceptable and easy to use for both healthy individuals and cardiac surgery patients.

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Antiplatelet therapy for coronary artery disease in 2023: current status and future prospects

Cited by 3 publications

References 134 publications

1- Versus 3-Month DAPT in Older Patients at a High Bleeding Risk Undergoing PCI: Insights from the XIENCE Short DAPT Global Program

1- Versus 3-Month DAPT in Older Patients at a High Bleeding Risk Undergoing PCI: Insights from the XIENCE Short DAPT Global Program

Second-generation everolimus-eluting intracoronary stents: a comprehensive review of the clinical evidence

The Neurophysiological Effects of Virtual Reality Application and Perspectives of Using for Multitasking Training in Cardiac Surgery Patients: Pilot Study

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