Antiproliferative activity of Citrus juices and HPLC evaluation of their flavonoid composition

Elucidation of the flavonoid and furocoumarin composition and radical-scavenging activity of green and ripe chinotto (Citrus myrtifolia Raf.) fruit tissues, leaves and seeds

“…Very few papers in the literature have dealt with the composition of the various parts of its fruit and leaves. In particular, four flavonoid glycosides (Camarda, Di Stefano, Del Bosco, & Schillaci, 2007;Cautela, Pirrello, Esposito, & Minasi, 2004) and ten carotenoids (Fanciullino et al, 2006) had been described for the juice, along with the composition of the essential oil fraction obtained from peel and leaves (Lota, de Rocca Serra, Jacquemond, Tomi, & Casanova, 2001). We recently reported on the flavonoid and furocoumarin distribution in the juice from green and ripe chinotto fruits (Barreca, Bellocco, Caristi, Leuzzi, & Gattuso, 2010a), identifying eleven derivatives and confirming, by comparing the flavonoid fingerprints (Robards, Li, Antolovich, & Boyd, 1997), its close taxonomical relations with C. aurantium L. (Barreca, Bellocco, Caristi, Leuzzi, & Gattuso, 2011a) and C. bergamia Risso (Gattuso, Barreca, Caristi, Gargiulli, & Leuzzi, 2007b;Gattuso et al, 2006).…”

Preparation of a polymethoxyflavone-rich fraction (PRF) of Citrus sunki Hort. ex Tanaka and its antiproliferative effects

“…Citrus plants are rich sources of health-promoting substances (Camarda, Stefano, Bosco, & Schillaci, 2007), and they contain a wide range of flavonoid constituents. Some of these, such as hesperidin, naringin, and polymethoxyflavones (PMFs), are characteristic of citrus plants, while others, such as rutin and quercetin, are common in the plant kingdom (Nogata et al, 2006).…”

Flavonoid Composition and Antioxidant Activity of Juices from Chinotto (Citrus × myrtifolia Raf.) Fruits at Different Ripening Stages

“…Flavone-C-glucoside (1 and 2), Flavone-O-glycoside (6), Flavanone-O-glycoside(3)(4)(5)(7)(8)(9), and Furocoumarin (10 and 11) Contents in C.…”