Antipyretic activity of Guduchi Ghrita formulations in albino rats

Ashok, B K; Ravishankar, B; Prajapati, PK; Bhat, Savitha D

doi:10.4103/0974-8520.77162

Cited by 26 publications

(14 citation statements)

References 14 publications

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“…The results revealed that the body temperature was elevated 18 h after the injection of this pyrogenic agent which continues to elevate up to the 4th h after initiation of fever in the positive control group. These results were in accordance with other research …”

Section: Discussionsupporting

confidence: 94%

Synergistic analgesic, anti‐pyretic and anti‐inflammatory effects of extra virgin olive oil and ibuprofen in different experimental models of albino mice

et al. 2017

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Section: Discussionsupporting

confidence: 94%

Synergistic analgesic, anti‐pyretic and anti‐inflammatory effects of extra virgin olive oil and ibuprofen in different experimental models of albino mice

et al. 2017

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“…Fever, inflammation, and pain are traditionally treated with T. cordifolia preparations ( Ashok et al., 2011 , Hussain et al., 2015 ). These preparations can reduce carrageenan-induced edema, indicating their anti-inflammatory potential ( Biswajyoti et al., 2014 ).…”

Section: Promising Pharmacological Activities Of Guduchi ( mentioning

confidence: 99%

Using Guduchi (Tinospora cordifolia) as an eco-friendly feed supplement in human and poultry nutrition

et al. 2020

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Guduchi ( Tinospora cordifolia ) is a well-recognized and widely distributed traditional plant that is used successfully in Indian Ayurveda medicine. T. cordifolia has shown many promising biological activities, such as antioxidative, antimicrobial, antihyperglycemic, anti-inflammatory, osteoprotective, hepatoprotective, antidiarrheal, and antistress effects. Guduchi is a rich source of protein and micronutrients, such as iron, zinc, copper, calcium, phosphorus, and manganese. It also contains many secondary plant metabolites, such as terpenes, alkaloids, flavonoids, steroids, and glycosides. Based on previous studies in poultry, the supplementation levels of Guduchi range from 1 to 5 g/kg of diet (different sources, such as powder, extracts, roots, and leaves, have been used). It was suggested that this variation in supplementation levels depends on different factors, including the extraction method, the supplementation proposed, the method of supplementation (either in feed or drinking water), and the species and physiological status of the birds. Generally, dietary supplementation of poultry broilers with T. cordifolia yielded positive impacts on growth performance, body gains (increased by 4.8%), dressing percentage (increased by 7.1%), meat quality traits, and the shelf life of the meat. In addition, T. cordifolia exerted a palliative effect on the general health status of the birds through reducing live enzymes and plasma uric acids and enhancing the immune response, as indicated by the leukocyte count, hemagglutinin titer, interleukin activity, and mortality levels. Further investigations concluded that T. cordifolia showed strong antimicrobial effects against Escherichia coli and Salmonella enteritidis , with subsequent reductions in mortality. Moreover, T. cordifolia showed an ability to improve humoral and cell-mediated immunity against Newcastle disease, infectious anemia, gout, and aflatoxicosis. The current review discusses many beneficial properties of T. cordifolia , although the lack of pharmacological trials limits the use of this extract in poultry. Further research should be performed regarding the composition of the active compound, the possible mechanisms of action, and the effective doses to fully understand the activities and benefits of T. cordifolia as a growth performance improvement supplement.

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“…According to the classical view, the genesis of fever is precipitated by means of inflammatory mediators (i.e., cytokines, namely interleukin-1, interleukin-6, tumor necrosis factor, and others) that are predominantly released by activated peripheral mononuclear phagocytes and different immune cells [36,37]. Due to the fact that direct get admission to of the large hydrophilic cytokine proteins to the temperature-controlling brain buildings within the pre-optic/anterior hypothalamic areas is prevented by means of the blood-brain barrier, the mechanisms described under have been cautioned for producing pyrexia [38]. The ethanolic extract of the flora of M. concanensis also showed antipyretic activity.…”

Section: Antipyretic Activitiesmentioning

confidence: 99%

Pharmacological Importance of Moringa Concanensis Nimmo Leaf: An Overview

Singh

Mishra

Singh

2019

Asian J Pharm Clin Res

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In the current years, the use of traditional medicine is increasing and gaining popularity. The extracts of Moringa concanensis Nimmo leaves have reported many medicinal uses. In the previous few decades, a massive quantity of scientific facts concerning plants, crude extracts, and quite a number supplies from plant life as medicinal dealers has come to light. M. concanensis is a plant whose components are oftentimes used in the medicinal treatments. There are good sized anecdotal facts about the organic undertaking of M. concanensis which includes anticancerous, antibacterial, antifungal, analgesic, and anti-inflammatory type of activities. The leaves of M. concanensis had been located to contain a higher quantity of triterpenoids and flavonoids. The existing assessment includes the phytochemical, ethnopharmacological, and pharmacological reviews of M. concanensis. The future scope of the plant has been emphasized with a view to isolate bioactive moieties which should be used for multifarious biological activities.

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Antipyretic activity of Guduchi Ghrita formulations in albino rats

Cited by 26 publications

References 14 publications

Synergistic analgesic, anti‐pyretic and anti‐inflammatory effects of extra virgin olive oil and ibuprofen in different experimental models of albino mice

Synergistic analgesic, anti‐pyretic and anti‐inflammatory effects of extra virgin olive oil and ibuprofen in different experimental models of albino mice

Using Guduchi (Tinospora cordifolia) as an eco-friendly feed supplement in human and poultry nutrition

Pharmacological Importance of Moringa Concanensis Nimmo Leaf: An Overview

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