Antischistosomal Activity of Essential Oils: An Updated Review

Crotti, Antônio Eduardo Miller; Pagotti, Mariana Cintra; Magalhães, Lizandra G.; Oliveira, Tatiana de Paula

doi:10.1002/cbdv.202100909

Cited by 4 publications

(9 citation statements)

References 44 publications

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“…Recently, many researchers have reconsidered them, analyzing their antimicrobial antifungal and antioxidant capacity [ 5 ]. EOs are widely reported as possessing antimicrobial, antimycotic, antiparasitic and insecticidal properties against human pathogens [ 6 , 7 , 8 , 9 , 10 , 11 ]. The antiviral efficacy of EOs has also been evaluated [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Essential Oils and Hydrolates on the Infectivity of Murine Norovirus

Cozzi

Vicenza

Battistini

et al. 2023

Viruses

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The use of natural substances with antiviral properties might reduce foodborne viral diseases. In this study, we evaluated the virucidal effect of Citrus limon and Thymus serpyllum essential oils (EOs) and of Citrus Limon, Thymus serpyllum and Thymus vulgaris hydrolates on murine norovirus (MNV), a human norovirus surrogate. To assess the virucidal effect of these natural substances, the reduction in viral infectivity was estimated by comparing the TCID50/mL of untreated viral suspension and the viral suspension treated with hydrolates and EOs at different concentrations. The results showed a natural loss of infectivity of the untreated virus after 24 h of approx. 1 log. The EO (1%) of T. serpyllum, and hydrolates (1% and 2%) of T. serpyllum and T. vulgaris immediately caused a reduction in MNV infectivity of about 2 log but did not provide a further significant decrease after 24 h. Instead, the EO (1%) and hydrolate (1% and 2%) of C. limon exerted an immediate reduction in the viral infectivity of about 1.3 log and 1 log, respectively, followed by a further reduction in infectivity of 1 log after 24 h for the hydrolate. These results will allow for the implementation of a depuration treatment based on the use of these natural compounds.

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Section: Introductionmentioning

confidence: 99%

Effects of Essential Oils and Hydrolates on the Infectivity of Murine Norovirus

Cozzi

Vicenza

Battistini

et al. 2023

Viruses

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“…1 Praziquantel (PZQ) is the only medication that is currently effective against all the species of schistosome; however, it does not prevent re-infections and is inactive against juvenile schistosomes, besides having limited effect on already developed liver and spleen lesions. 2,3 These limitations, in combination with considerable concern about the development of PZQ resistance, have motivated the scientific community to call for research and development of novel and inexpensive drugs against schistosomiasis. 3,4 In this scenario, several essential oils, extracts, and isolated compounds obtained from plants have been investigated for their schistosomicidal potential.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the in vitro antischistosomal activity of Bidens sulphurea (Cav.) Sch. Bip. (Asteraceae)

Silva,

Zago,

Paula

et al. 2023

rmusc

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In this study, the in vitro schistosomicidal properties of the n-hexane (BS-1), dichlorometane (BS-2) and methanol (BS-3) extracts from the leaves of Bidens sulphurea against Schistosoma mansoni were investigated. The extract BS-3 at 200 µg/mL caused the death of 100% of the male and 75% of the female adult worms and promoted the separation of 75% of the coupled pairs into individual males and females within 120h. This extract was partitioned in n-hexane, dichloromethane, ethyl acetate, and methanol, furnishing the fractions BS-3.1, BS-3.2, BS-3.3, and BS-3.4, respectively. The fraction BS-3.2 was the most active, causing the death of all the male and female adult worms after 120 h, and the separation of all the coupled pairs of worms in the same period. The results of this preliminary study demonstrated for the first time the in vitro antischistosomal activity of B. sulphurea extracts.

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“…No entanto, esse parâmetro deve ser avaliado em concentrações subletais (ou seja, que não sejam capazes de matar os vermes) e que não separam os vermes acasalados, permitindo assim a produção dos ovos. Dentre os OEs testados, vários apresentaram efeitos sobre a oviposição, desenvolvimento de ovos e separação de vermes adultos de S. mansoni acasalados(Oliveira et al, 2022). Por exemplo, na concentração de 100 µg/mL, os OEs de F. vulgare, P. neochilus e T. erecta promoveram a separação de 100% dos vermes adultos acasalados de S. mansoni(Caixeta et al., 2011, Tonuci et al, 2012, Wakabayashi et al, 2015).…”

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Fitoquímica: potencialidades biológicas dos biomas brasileiros

Miranda¹

2022

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Parecer e revisão por paresOs textos que compõem esta obra foram submetidos para avaliação do Conselho Editorial da Editora Científica Digital, bem como revisados por pares, sendo indicados para a publicação.O conteúdo dos capítulos e seus dados e sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores e autoras.É permitido o download e compartilhamento desta obra desde que pela origem da publicação e no formato Acesso Livre (Open Access), com os créditos atribuídos aos autores e autoras, mas sem a possibilidade de alteração de nenhuma forma, catalogação em plataformas de acesso restrito e utilização para fins comerciais.Esta obra está licenciada com uma Licença Creative Commons Atribuição-Não Comercial-Sem Derivações 4.0 Internacional (CC BY-NC-ND 4.0). Dados Internacionais de Catalogação na Publicação (CIP) F546Fitoquímica: potencialidades biológicas dos biomas brasileiros / Mayker Lazaro Dantas Miranda (Organizador). -Guarujá-SP: Científica Digital, 2022.

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Antischistosomal Activity of Essential Oils: An Updated Review

Cited by 4 publications

References 44 publications

Effects of Essential Oils and Hydrolates on the Infectivity of Murine Norovirus

Effects of Essential Oils and Hydrolates on the Infectivity of Murine Norovirus

Evaluation of the in vitro antischistosomal activity of Bidens sulphurea (Cav.) Sch. Bip. (Asteraceae)

Fitoquímica: potencialidades biológicas dos biomas brasileiros

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