Antiurolithiatic activity of aqueous extract of bark of moringa oleifera (lam.) in rats

Fahad, Jameel Fahad Jameel; VIJAYALAKSHMI, .; Kumar, Manoj; Sanjeeva,; Kodancha, G. Prabhath; Benegal, Adarsh; Udupa, A. L.; Rathnakar, U P

doi:10.4236/health.2010.24053

Cited by 15 publications

(7 citation statements)

References 4 publications

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“…The antiurolithic activity was exhibited insolvent and ethanolic extract of the bark of M. oleifera and additionally noted that the reduction of weight of the stone generated victimization ethylene glycol evoked urolithiasis activity [43].…”

Section: Antiurolithic Activitymentioning

confidence: 90%

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Phytoassembly and Pharmacological Activity on Moringa Oleifera: A Review

Malage¹,

Jadhav²,

Yogekar³

et al. 2020

Asian J Pharm Clin Res

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Moringa oleifera is a plant that has copious medicative properties and widely known as “drumstick plant” or “horseradish plant” and most widely vascular plant in India. This is a nutritional plant (herb) that consists of many pharmacological and biological exertion such as antiasthmatic, diuretic, antiepileptic, cardiovascular as well as antioxidants and also beneficial in wound healing enterprise. The anti-asthmatic action of M. oleifera seeds kernel ethanolic extract evoked by histamine and acetylcholine aerosol. Pre-treatment by ethanol gives the extract of M. oleifera also diminished carrageenan convinced rat paw edema that was comparable to standard diclofenac sodium. This review summarizes the biological exertion such as a cardiovascular, diuretic, and biological activities such as antimicrobial, antiepileptic, and anti-allergic activities and also provides pharmacological activities in essence anti-cancer, anti-diabetic, and anti-asthmatic activities.

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Section: Antiurolithic Activitymentioning

confidence: 90%

“…Flavonoids, tannins, and alkaloids check parts were additionally ascertained to be accountable for antimicrobial activity [52] wherever pterygospermin was noted to be chargeable for antifungal activity [43].…”

Section: Immunomodulatory and Antidiarrheal Activitymentioning

confidence: 99%

Phytoassembly and Pharmacological Activity on Moringa Oleifera: A Review

Malage¹,

Jadhav²,

Yogekar³

et al. 2020

Asian J Pharm Clin Res

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“…It showed reduction in weight of stone produced using ethylene glycol induced urothiasis. It also possesses both preventive and curative property [ 13 ].…”

Section: Morphologymentioning

confidence: 99%

Phytochemistry and Pharmacology of Moringa oleifera Lam

Paikra¹,

Dhongade²,

Gidwani³

2017

J. Pharmacopunct

123

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Moringa oleifera Lam. or munga is one of the most important plant widely cultivated in India. It belongs to family Moringaceae. This plant is widely used as nutritional herb and contains valuable pharmacological action like anti-asthmatic, anti-diabetic, hepatoprotective, anti-inflammatory, anti- fertility, anti-cancer, anti-microbial, anti-oxidant, cardiovascular, anti-ulcer, CNS activity, anti-allergic, wound healing, analgesic, and antipyretic activity, Moringa oleifera Lam. The plant is also known as Horse - radish tree, Drumstick tree. Every part of this plant contains a valuable medicinal feature. It contain rich source of the vitamin A, vitamin C and milk protein. Different types of active phytoconstituents like alkaloids, protein, quinine, saponins, flavonoids, tannin, steroids, glycosides, fixed oil and fats are present. This plant is also found in the tropical regions. Some other constituents are niazinin A, niazinin B and niazimicin A, niaziminin B. The present review discusses the phytochemical composition, medicinal uses & pharmacological activity of this plant.

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“…(Moringaceae) is locally known as Shahjna. Different parts of this plant are used in the indigenous system of medicine as an anti-inflammatory (Kooltheat et al, 2014), anthelmintic (Rastogi et al, 2009), analgesic (Manaheji et al, 2011), antioxidant (Chang et al, 2012), hepatoprotective (Hamza, 2010), antiurolithiatic (Fahad et al, 2010) antitoxic (Agrawal et al, 2013b), and for the treatment of a variety of human ailments such as heart complaints (Panda et al, 2013), eye disease, dyspepsia, enlargement of spleen (Singh & Sharma, 2012), and ulcers (Choudhary et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Co-administration of adjuvants along withMoringa oleiferaattenuates beryllium-induced oxidative stress and histopathological alterations in rats

Agrawal

Nirala

Shukla

et al. 2015

Pharmaceutical Biology

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Context: Moringa oleifera Lam. (Moringaceae) is a rich source of antioxidants. All parts of the plant are medicinally important and have been used as traditional medicine for a variety of human ailments in India. Objective: Therapeutic efficacy of adjuvants with M. oleifera (MO) root extract was investigated against beryllium-induced oxidative stress. Materials and methods: Hydroalcoholic (50% v/v) root extract of M. oleifera (150 mg/kg, p.o.) alone and combinations of M. oleifera with either piperine (2.5 mg/kg, p.o.) or curcumin (5.0 mg/kg, p.o.) daily for 1 week were administered in experimental rats against beryllium toxicity (1.0 mg/kg, i.p. daily for 5 weeks). Oxidative stress parameters including blood sugar, G-6-Pase in liver, and DNA damage were analyzed. Histopathological changes in liver and kidney were also observed. Results: Beryllium enhanced lipid peroxidation (LPO), depleted reduced glutathione (GSH) and antioxidant enzymes activities, decreased blood sugar and G-6-Pase activity, and did not damage DNA. Histologically, liver was observed with structural loss and disintegration of hepatocytes, heavy vacuolation in hepatocytes, and kidney was observed with constriction of glomeruli and hypertrophy in epithelial cells of uriniferous tubules. Therapy of M. oleifera with piperine was effective; however, combination of M. oleifera with curcumin showed better therapeutic effect by reduction of LPO, elevated GSH level, maintained antioxidant enzymes activities, restored blood sugar, and G-6-Pase activity in liver together with almost normal histoarchitecture of liver and kidney. Discussion and conclusion: Curcumin enhanced therapeutic efficacy of M. oleifera root extract and showed better antioxidant potential against beryllium toxicity.

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Antiurolithiatic activity of aqueous extract of bark of moringa oleifera (lam.) in rats

Cited by 15 publications

References 4 publications

Phytoassembly and Pharmacological Activity on Moringa Oleifera: A Review

Phytoassembly and Pharmacological Activity on Moringa Oleifera: A Review

Phytochemistry and Pharmacology of Moringa oleifera Lam

Co-administration of adjuvants along withMoringa oleiferaattenuates beryllium-induced oxidative stress and histopathological alterations in rats

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