Anxiety and depression among Greek men with primary erectile dysfunction and premature ejaculation

Mourikis, Iraklis; Antoniou, M.; Matsouka, Efi; Vousoura, Eleni; Tzavara, Chara; Ekizoglou, Chrysa; Papadimitriou, George N.; Vaidakis, Nikolaos; Zervas, Iannis M.

doi:10.1186/s12991-015-0074-y

Cited by 49 publications

(44 citation statements)

References 58 publications

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“…It should be noted however that anxiety and depression may also be the effect rather than the cause of PE and several recent studies have confirmed the bi-directional relatiopnship between anxiety, depression and PE (50-54). …”

Section: Psychological Risk Factormentioning

confidence: 99%

The pathophysiology of acquired premature ejaculation

McMahon¹,

Jannini²,

Şerefoğlu³

et al. 2016

Transl. Androl. Urol.

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The second Ad Hoc International Society for Sexual Medicine (ISSM) Committee for the Definition of Premature Ejaculation defined acquired premature ejaculation (PE) as a male sexual dysfunction characterized by a the development of a clinically significant and bothersome reduction in ejaculation latency time in men with previous normal ejaculatory experiences, often to about 3 minutes or less, the inability to delay ejaculation on all or nearly all vaginal penetrations, and the presence of negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy. The literature contains a diverse range of biological and psychological etiological theories. Acquired PE is commonly due to sexual performance anxiety, psychological or relationship problems, erectile dysfunction (ED), and occasionally prostatitis and hyperthyroidism, consistent with the predominant organic etiology of acquired PE, men with this complaint are usually older, have a higher mean BMI and a greater incidence of comorbid disease including hypertension, sexual desire disorder, diabetes mellitus, chronic prostatitis, and ED compared to lifelong, variable and subjective PE.

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Section: Psychological Risk Factormentioning

confidence: 99%

The pathophysiology of acquired premature ejaculation

McMahon¹,

Jannini²,

Şerefoğlu³

et al. 2016

Transl. Androl. Urol.

View full text Add to dashboard Cite

show abstract

“…Anxiety and depression evaluated by the SCL‐90‐R subscales were correlated with IIEF‐5 scores in type 2 diabetes mellitus patients (Chen et al, 2017). Furthermore, among patients with ED alone or ED combined with premature ejaculation, patients diagnosed with worse ED (measured by the IIEF) had worse psychological conditions (Mourikis et al, 2015). The level of trait anxiety was also positively correlated with ED (measured by the IIEF) (Erden & Kaya, 2015).…”

Section: Introductionmentioning

confidence: 99%

Is milder psychological stress responsible for more severe erectile dysfunction?

Liao

Tang

et al. 2020

Andrologia

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China is a sexually conservative country compared with Western countries. To evaluate the psychological characteristics of Chinese erectile dysfunction (ED) patients, we conducted a cross‐sectional study of 153 ED outpatients. Patients were interviewed with the Structured Interview on Erectile Dysfunction (SIEDY) for pathogenic quantification. ED was measured by International Index of Erectile Function (IIEF). Depression and anxiety were evaluated with 9‐item Patient Health Questionnaire (PHQ‐9) and 7‐item Generalised Anxiety Disorder Scale (GAD‐7) respectively. Most patients (74.5%) were <40 years old. IIEF‐5 were significantly correlated with SIEDY scale 3 (r = .16, p = .040) and GAD‐7 (p = .15, p = .033). The SIEDY scale 1 increased with age, but the IIEF‐5, SIEDY scale 3, PHQ‐9 and GAD‐7 decreased with age. A negative correlation was observed between ED and psychological stress, which conflicts with many Western‐country studies. Younger patients were characterised by milder ED but more psychological stress, while older patients were characterised by worse ED but less psychological stress. Which may be responsible for the conflicting result. Meanwhile, the much younger age distribution among Chinese ED outpatients may indicate that quite a few older ED patients (≥40 years) in China do not seek outpatient service which should merit more attention.

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“…It has been shown in several studies that anxiety and depression and PE have a bidirectional relationship (28)(29)(30)(31). In particular, it is stated that anxiety reduces the time of ejaculation by affecting the emission phase by activation of sympathetic nervous system.…”

Section: Discussionmentioning

confidence: 99%

Is there any Relationship Between Acquired Premature Ejaculation and Blood Vitamin B12 or Folic Acid Levels?

Canat¹,

Değirmentepe²,

Can³

et al. 2019

eamr

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To investigate the relationship between acquired premature ejaculation (PE) and serum vitamin B12 or folic acid levels. Methods: A total of 93 patients with acquired PE and 69 controls without PE were included the study. All patients fulfilling the criteria of the International Society for Sexual Medicine Committee were considered to have acquired PE. Serum vitamin B12 and folic acid levels were evaluated in all men included in the study. Results: Compared to controls, vitamin B12 levels were lower in patients with acquired PE (336.5±142.9 pg/mL vs. 356.0±162.5 pg/mL); however, there was no statistically significant difference between the two groups (p=0.576). There was no significant difference in folic acid levels between patients with acquired PE and controls (7.5±3.4 ng/mL vs. 7.3±3.1 ng/mL, p=0.853). Conclusion: There is no relationship between serum vitamin B12 and folic acid levels and acquired PE. The evaluation of these vitamins should not be recommended to explore the etiology and risk factors of acquired PE.

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Anxiety and depression among Greek men with primary erectile dysfunction and premature ejaculation

Cited by 49 publications

References 58 publications

The pathophysiology of acquired premature ejaculation

The pathophysiology of acquired premature ejaculation

Is milder psychological stress responsible for more severe erectile dysfunction?

Is there any Relationship Between Acquired Premature Ejaculation and Blood Vitamin B12 or Folic Acid Levels?

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