Anxiety and Depression as Risk Factors for Oral Lichen planus

Vallejo, Mónica; Huerta, Gloria M.; Cerero, R; Seoane, Juan

doi:10.1159/000051777

Cited by 83 publications

(16 citation statements)

References 21 publications

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“…Although the etiology of OLP remains uncertain, there have been reports that described many systemic disorders linked to OLP such as metabolic syndrome [25], mental disorders [26], immune disease [27,28] and viral infection [29]. The association of these pathologies with OLP appears to depend upon geographic factors [30].…”

Section: Discussionmentioning

confidence: 99%

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

García-Pola¹,

Llorente-Pendás²,

Romero³

et al. 2016

Dermatology

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Background: Thyroid disease has been mentioned to have a possible relation to the development of oral lichen planus (OLP). Objective: Because goiter is considered endemic in many countries, we proposed to determine whether thyroid disease constitutes a comorbidity of OLP. Methods: Two hundred and fifteen patients diagnosed as having OLP were evaluated concerning their serum thyroid-stimulating hormone and thyroxine (T₄) levels. The results were contrasted with those obtained in control series of the same number of subjects matched for age and sex. Results: Diagnosis of thyroid disease was present in 15.3% of OLP patients (33/215) and in 5.2% (12/215) of the control group. In relation to OLP patients, the odds ratio of presence of thyroid disorders was 3.06 and that of using levothyroxine medication 3.21. Conclusions: In the present study, OLP patients were associated with thyroid disease, specifically with hypothyroidism. Because most thyroid patients need T₄ treatment, our findings confirmed that OLP and thyroid disease could be comorbidities.

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Section: Discussionmentioning

confidence: 99%

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

García-Pola¹,

Llorente-Pendás²,

Romero³

et al. 2016

Dermatology

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“…Around 63.2% of patients suffered from borderline or morbid anxiety. The results are in accordance with McCartan et al ., (1995), Vallejo et al ., (2001),[5] Soto Araya et al ., (2004)[1] and not in accordance with Allen et al ., (1986)[9] and Rodstrom (2001). [6] In the present study, HAD Scale was used for identifying and quantifying the two most common forms of psychological disturbances in patients, namely anxiety and depression.…”

Section: Discussionmentioning

confidence: 99%

“…[145678] Recent studies using instruments to assess the stress in these patients have resulted in conflicting reports [Table 1]. …”

Section: Introductionmentioning

confidence: 99%

Oral lichen planus and stress: An appraisal

Sandhu¹,

Sandhu²,

Bansal³

et al. 2014

Contemp Clin Dent

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Introduction:Oral lichen planus (OLP) is a chronic inflammatory disease characterized by bilateral white striations or plaques on the buccal mucosa, tongue or gingiva that has a multifactorial etiology, where the psychogenic factors seem to play an important role.Purpose:The aim of this study was to determine the existing relation between the OLP and psychological alterations of the patient, such as stress, anxiety, and depression.Materials and Methods:Hospital anxiety and depression scale was applied for psychometric analysis.Results:The study indicates a definitive relationship between a stressful life event and onset and progression of OLP.Conclusion:Stress management and bereavement counseling should be a part of management protocol of OLP.

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“…Our findings are in line with previous studies thereby suggesting an association between psychiatric disorders and chronic skin diseases. For example, high levels of depression and anxiety have been observed in patients with skin diseases such as psoriasis vulgaris [23], atopic dermatitis [3], lichen planus [24] and Behcet's disease [25]. …”

Section: Discussionmentioning

confidence: 99%

Are skin disorders related to work strain in hospital workers? A cross-sectional study

et al. 2011

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BackgroundTo evaluate whether occupational stress factors (high demands, low control, low social support, strain, and iso-strain) are associated with skin disorders in hospital workers and whether psychological problems, such as anxiety and depression, act as potential mechanisms through which occupational stress factors are associated with skin disorders.Methods1,744 hospital workers were invited to answer a questionnaire concerning the occurrence of skin disorders and psychosocial factors at work. The abbreviated Italian version of the Demand/Control model (Karasek) was used to assess perceived work strain, while the Goldberg scales were used to assess anxiety and depression. Analyses were adjusted for age, gender, occupation, latex glove use and history of atopy.ResultsOf the participants, 25% reported hand dermatitis in the previous 12 months and 35% had been affected by skin disorders in other parts of the body. High job demands (OR = 1.09 CI95% 1.05-1.14), low social support (OR = 0.90, CI95% 0.87-0.93), high strain (OR = 1.54 CI95% 1.20-1.98) and high iso-strain (1.66 CI95% 1.27-2.19) were all associated with a higher prevalence of reported hand skin disorders. Both depression (OR = 2.50 CI95% 1.99-3.14) and anxiety (OR = 2.29 CI95% 1.81-2.89) were associated with higher risk of hand skin disorders. The same pattern was observed for dermatological complaints in other parts of the body. Only a slight reduction in the association between occupational stress variables and skin disorders was observed after including depression and anxiety in the model.ConclusionsJob stress plays a significant role in triggering skin disorders among hospital workers and psychological problems do not appear to be the mechanism behind this association. Occupational health education and training should focus on reducing job demands and occupational stress in order to prevent skin problems among hospital workers.

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Anxiety and Depression as Risk Factors for Oral Lichen planus

Cited by 83 publications

References 21 publications

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

Thyroid Disease and Oral Lichen Planus as Comorbidity: A Prospective Case-Control Study

Oral lichen planus and stress: An appraisal

Are skin disorders related to work strain in hospital workers? A cross-sectional study

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