Aphasia and agraphia in lesions of the posterior internal capsule and putamen

Tanrıdağ, Oğuz; Kirshner, Howard S.

doi:10.1212/wnl.35.12.1797

Cited by 46 publications

(10 citation statements)

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“…In the lesion-based literature, peripheral processes have been most consistently associated with a left frontal–parietal network including, but not limited to, the dorsal premotor cortex and SPL (Exner, 1881; Ritaccio et al, 1992; Tohgi et al, 1995; Lubrano et al, 2004; Roux et al, 2009). In addition, peripheral dysgraphias have been described that are associated with damage to neural regions involved in general motor processing (not specifically in written language production) such as motor cortex, cerebellum, and various sub-cortical structures, e.g., caudate, putamen, and thalamus (Tanridag and Kirshner, 1985; Pramstaller and Marsden, 1996; Denes et al, 2005; Fournier Del Castillo et al, 2011). Finally, it is worth mentioning that spatial dysgraphias have been associated with some forms of spatial neglect (e.g., Caramazza and Hillis, 1990).…”

Section: Introductionmentioning

confidence: 99%

Examining the Central and Peripheral Processes of Written Word Production Through Meta-Analysis

Purcell¹,

Turkeltaub²,

Eden³

et al. 2011

Front. Psychology

198

242

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Producing written words requires “central” cognitive processes (such as orthographic long-term and working memory) as well as more peripheral processes responsible for generating the motor actions needed for producing written words in a variety of formats (handwriting, typing, etc.). In recent years, various functional neuroimaging studies have examined the neural substrates underlying the central and peripheral processes of written word production. This study provides the first quantitative meta-analysis of these studies by applying activation likelihood estimation (ALE) methods (Turkeltaub et al., 2002). For alphabet languages, we identified 11 studies (with a total of 17 experimental contrasts) that had been designed to isolate central and/or peripheral processes of word spelling (total number of participants = 146). Three ALE meta-analyses were carried out. One involved the complete set of 17 contrasts; two others were applied to subsets of contrasts to distinguish the neural substrates of central from peripheral processes. These analyses identified a network of brain regions reliably associated with the central and peripheral processes of word spelling. Among the many significant results, is the finding that the regions with the greatest correspondence across studies were in the left inferior temporal/fusiform gyri and left inferior frontal gyrus. Furthermore, although the angular gyrus (AG) has traditionally been identified as a key site within the written word production network, none of the meta-analyses found it to be a consistent site of activation, identifying instead a region just superior/medial to the left AG in the left posterior intraparietal sulcus. These meta-analyses and the discussion of results provide a valuable foundation upon which future studies that examine the neural basis of written word production can build.

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Section: Introductionmentioning

confidence: 99%

Examining the Central and Peripheral Processes of Written Word Production Through Meta-Analysis

Purcell¹,

Turkeltaub²,

Eden³

et al. 2011

Front. Psychology

198

242

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“…Cognitive disorders have been reported in selected cases or in short series. Indeed, left lesions could be the source of aphasia [10][11][12][13], which is most often of the transcortical motor type. Others deficits could be observed, such as constructive apraxia [12] and amnesic syndrome [14].…”

Section: Introductionmentioning

confidence: 99%

An evaluation of cognitive disorders after anterior choroidal artery infarction

Rousseaux¹,

Cabaret²,

Serafi³

et al. 2008

J Neurol

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Anterior choroidal artery infarction (AChAI) can be the source of aphasia and spatial neglect, but we have no idea of the other possible cognitive disorders. Here, we investigated these disorders in a relatively large cohort of AChAI patients. Twenty patients with relatively recent infarction (left side: 13; mean delay = 47.4 days; 10 men; mean age = 59.6; mean education level, EL = 10.3) were included. We assessed nonspatial attention (alertness, Go Nogo, divided attention and visual vigilance from the computerized test TEA), spatial attention (bell test), language (BDAE) orientation (time, place), short-term memory (forward and backward digit spans, spatial span), executive functioning (WCST, TMT A and B, categorial evocation), delayed memory (Buschke verbal test, Rey figure test), and retrograde memory (questionnaire on famous events). The performance level was compared with that of 20 control subjects matched in age and EL. AChAI patients were impaired in several tests of attention (slowness, increase in omission and error rate), executive functioning (TMT B; categorical evocation) and delayed memory. Conversely, we found preservation of spatial attention, language, orientation, short-term memory, WCST, and retrograde memory. In conclusion, at the secondary phase post-stroke, these patients can present with moderate disorders of attention, memory and executive functioning, which are clearly less severe than what is usually observed following thalamic or cortical lesions.

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“…Post-stroke language disorders are frequent and include aphasia, alexia, agraphia and acalculia. Based on CT scan findings, aphasia with variable expressive and receptive components have been described with lesions in the dominant anterior limb of the internal capsule, the head of the caudate, and the putamen and with the lesions in the posterior limb of the dominant internal capsule (7,8). There are different definitions of aphasias, but the most widely accepted neurologic and/or neuropsychological definition is that aphasia is a loss or impairment of verbal communication, which occurs as a consequence of brain dysfunction.…”

Section: Discussionmentioning

confidence: 99%