Apocrine carcinoma in the parotid gland and in the submandibular region

Francisco, Jairo Silva; Alfaro, Silvia Elena Navas; Oliveira, Daniela C. C.M.; Tonon, Sebastião; Dias, Eliane Pedra

doi:10.1016/s1808-8694(15)31314-8

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…The prognosis for cutaneous apocrine carcinoma is variable. There have been reports of local recurrences and regional lymph node metastasis occurring years after initial excision 10 …”

mentioning

confidence: 99%

Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides

Cham¹,

Niehans²,

Foman³

et al. 2007

Br J Dermatol

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References1 Smith F. The molecular genetics of keratin disorders. Am J Clin Dermatol 2003; 4:347-64. 2 Lane EB, McLean WHI. Keratins and skin disorders. J Pathol 2004; 204:355-66. 3 Ishida-Yamamoto A, McGrath JA, Judge MR et al. Selective involvement of keratins K1 and K10 in the cytoskeletal abnormality of epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma). J Invest Dermatol 1992; 99:19-26. 4 Rothnagel JA, Traupe H, Wojcik S et al. Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens. Nat Genet 1994; 7:485-90. 5 Kremer H, Zeeuwen P, McLean WHI et al. Ichthyosis bullosa of Siemens is caused by mutations in the keratin 2e gene. J Invest Dermatol 1994; 103:286-9. 6 McLean WHI, Morley SM, Lane EB et al. Ichthyosis bullosa of Siemens -a disease involving keratin 2e. J Invest Dermatol 1994; 103:277-81. 7 Akiyama M, Tsuji-Abe Y, Yanagihara M et al. Ichthyosis bullosa of Siemens: its correct diagnosis facilitated by molecular genetic testing. Br J Dermatol 2005; 152:1353-6. 8 Traupe H, Kolde G, Hamm H, Happle R. Ichthyosis bullosa of Siemens: a unique type of epidermolytic hyperkeratosis. J Am Acad Dermatol 1986; 14:1000-5. 9 Yang JM, Nam K, Kim HC et al. A novel glutamic acid to aspartic acid mutation of the 2B rod domain in the keratin 1 chain in epidermolytic hyperkeratosis. J Invest Dermatol 1999; 112:376-9. 10 Sun XK, Ma LL, Xie YQ et al. Keratin 1 and keratin 10 mutations causing epidermolytic hyperkeratosis in Chinese patient. J Dermatol Sci 2002; 29:195-200.Conflicts of interest: none declared. Fig 1. A well-demarcated, erythematous plaque with firm woody oedema involving the cheeks, chin and anterior neck.

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“…The prognosis for cutaneous apocrine carcinoma is variable. There have been reports of local recurrences and regional lymph node metastasis occurring years after initial excision 10 …”

mentioning

confidence: 99%

Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides

Cham¹,

Niehans²,

Foman³

et al. 2007

Br J Dermatol

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“…17 The therapeutic effect of chemotherapy on SGC has not been confirmed, only a few successful have been reported in single case reports. 18 According to previous literatures, the 5-year survival rate for SGC is less than 30%; the local recurrence rate is as high as 50%; and 60% of the patient exhibit metastasis within 2 years after surgery. 19,20 In the study of head and neck sweat gland adenocarcinoma (SGA), Unsal et al reported that the overall prognosis is relatively good: 5-, 10-, and 20-year diseasespecific survival at 94.6%, 89.6%, and 79.8%, respectively.…”

Section: Discussionmentioning

confidence: 95%

“…17 The therapeutic effect of chemotherapy on SGC has not been confirmed, only a few successful have been reported in single case reports. 18…”

Section: Discussionmentioning

confidence: 99%

Sweat Gland Carcinoma of the Head and Neck: Case Report and Literature Review

Zhang

Yin

et al. 2021

Ear Nose Throat J

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Introduction: The main aim of this article is to discuss and summarize the research advancements and the treatment methods for sweat gland carcinoma (SGC) based on 2 cases of SGC in our hospital and the related literature. Case Report: This article presents 2 patients with SGC who were treated in the China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases from 2007 to 2019. We analyzed the clinical features, therapies, and prognosis of the patients and searched for related literatures. Discussion: Two patients underwent extended resection for local lesions with no adjuvant radiotherapy. Neither local recurrence nor distant metastasis was detected during follow-up. Reviewing previous literature, the treatment of SGC includes surgical resection, radiotherapy, and chemotherapy. We have not found an effective treatment. The prognosis of SGC occurred in head and neck is relatively good compared with another primary-site location, primary surgical excision with safe resection margins and neck dissection is recommended.

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Anal Apocrine Carcinoma

Hall

Florell²,

Sklow³

et al. 2012

The American Journal of Dermatopathology

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Apocrine carcinoma (AC) is an extremely rare skin appendage tumor, which is located at lower dermal and subcutaneous tissue. We report a case of an anal AC arising from an apocrine adenoma in the anal region, which is only the second case reported in this region. A 71-year-old male presented to clinic with soreness in the anal region for 6 weeks. An excisional biopsy was performed. Histologically, the lesion was poorly circumscribed, infiltrative, and was composed of small to medium sized glands extending to the surgical margins. There were centrally dilated large glands with duct-like openings into the mucosal surface. The larger central glands contain periodic acid-Schiff-positive eosinophilic acellular secretions. At the periphery, there were smaller glands with significant cytologic atypia and numerous mitoses. A diagnosis of AC was made making it the second case report of this very rare malignancy in this region. Although ACs usually do not have a fatal outcome, there have been case reports of distant metastases and even death from this disease, making histologic distinction of this malignancy from a benign apocrine adenoma important. Wide local excision is typically the treatment of choice, although Mohs micrographic surgery has also been used with similar success.

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Apocrine carcinoma in the parotid gland and in the submandibular region

Cited by 3 publications

References 7 publications

Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides

Primary cutaneous apocrine carcinoma presenting as carcinoma erysipeloides

Sweat Gland Carcinoma of the Head and Neck: Case Report and Literature Review

Anal Apocrine Carcinoma

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