Apocrine chromhidrosis localized to the areola in an Indian female treated with topical capsaicin

Coloured sweat in two brothers: First report of familial chromhidrosis

“…Apocrine chromhidrosis is the most common endogenous form of the condition. It is most frequently noticed at the face and axillae but it has been noted at the areolae and has been reported to affect the perianal area only once . The patient, typically in the second to fourth decade of life, complains of sweat which is black, brown, green, blue or sometimes yellow in colour, most noticeable in situations where increased sweating is stimulated.…”

A Case of Late-Onset Genital Apocrine Chromhidrosis

“…1 Bugüne kadar literatürde bildirilen apokrin kromhidrozlu hastaların çoğunluğunda yüz, meme areolası ve aksilla etkilenmiştir. [12][13][14][15] Olgumuzda ise sadece genital bölgede renk değişikliği saptanmış-tır. Olgumuz, bildiğimiz kadarıyla literatürde yayımlanan ilk izole genital apokrin kromhidroz hastasıdır.…”

Chromhidrosis

“…Chromhidrosis is not associated with abnormal laboratory results; however, normal laboratory results can rule out other possibilities from the differential diagnosis. A review of the literature on treatment options for chromhidrosis demonstrates three main off-label treatment options for apocrine chromhidrosis: (1) topical capsaicin cream, 5,[17][18][19] (2) 20% aluminum chloride hexahydrate solution (Drysol), 3,7 and (3) botulinum toxin A. Normal blood bilirubin levels can rule out hyperbilirubinemia.…”

“…Normal blood bilirubin levels can rule out hyperbilirubinemia. 6,18 Chromhidrosis is likely to be a recurrent condition due to the lack of known effective treatments, 21 though symptoms may decrease with age due to natural regression of the apocrine glands. 15 Alkaptonuria, a metabolic condition resulting in darkening of the urine, can be ruled out through testing of urinary homogenistic acid levels.…”