Apoptosis in the hypoxia-induced cell damage

Effect of hypoxia on RAW264.7 macrophages apoptosis and signaling

“…It was previously shown that hypoxia severely impairs cell function, as well as cell viability, and the response of cells to hypoxia could be very different in different cell types and under different environments (Ho et al, 2006;Voicu et al, 1998). It has been reported that hypoxia may enhance apoptosis in a human hepatocyte line or lung adenocarcinoma cell line A549, or result in progressive arrest of cells in the G1 phase of the cell cycle (Cao et al, 2006;Vaporidi et al, 2005).…”