Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from <i>Vinca herbacea</i> Waldst. and kit

Gülçın, İlhami; Beydemır, Şükrü; Topal, Fevzi; Gagua, Natia; Bakuridze, A. Dzh.; Bayram, Recep; Gepdíremen, Akçahan

doi:10.3109/14756366.2011.604318

Cited by 71 publications

(32 citation statements)

References 23 publications

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“…ROS can cause tissue damage and it leads to various diseases 5,[41][42][43][44] . ROS, which involves free radicals such as OH and O 2 À radicals, and nonfree radical species such as H 2 O 2 and singlet oxygen ( 1 O 2 ) were known as different forms of activated oxygen [45][46][47][48] . On the other hand, cellular injury can initiate with various defensive mechanisms by ROS.…”

Section: Resultsmentioning

confidence: 99%

A comparative study on the antioxidant effects of hesperidin and ellagic acid against skeletal muscle ischemia/reperfusion injury

Akdemir

Gülçın

Karagöz

et al. 2016

Journal of Enzyme Inhibition and Medicinal Chemistry

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The antioxidant effects of ellagic acid (EA) and hesperidin (HES) against skeletal muscle ischemia/reperfusion injury (I/R) were performed. Hindlimb ischemia has been induced by tourniquet occlusion for 2 h on left hindlimb. At the end of ischemia, the tourniquate has been removed and initiated reperfusion for 2 h. EA (100 mg/kg) has been applied orally before ischemia/reperfusion in the EA + I/R group. HES (100 mg/kg) has been given orally in the HES + I/R group. The left gastrocnemius muscle has been harvested and stored immediately at À80 C until assessed for the levels of MDA and antioxidant enzymes activities. MDA level has statistically increased in I/R group (p50.05) compared to other groups. The muscle tissue antioxidant enzymes activities were lower than the other groups in the I/R group (p50.05). EA and HES treatments significantly reversed the damage level in I/R, also activity of tissue SOD increased in the EA + I/R and HES + I/R groups.

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Section: Resultsmentioning

confidence: 99%

A comparative study on the antioxidant effects of hesperidin and ellagic acid against skeletal muscle ischemia/reperfusion injury

Akdemir

Gülçın

Karagöz

et al. 2016

Journal of Enzyme Inhibition and Medicinal Chemistry

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“…Plants have been used for treatment of many diseases [19]. Phenolic compounds are the most widely occurring chemicals, which having strong antioxidant properties [20].…”

Section: Figure 1 Chromatograms Of Phenolic Antioxidants By Lc-ms/msmentioning

confidence: 99%

Antioxidant Activity of Flaxseed (Linum usitatissimum L.) shell and Analysis of Its Polyphenol Contents by LC-MS/MS

Han¹,

Yilmaz²,

Gülçin³

2018

Rec.Nat.Prod.

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Flaxseed (Linum usitatissimum L.) is important source of oil and protein for industrial, pharmaceutical, and nutritional applications. In order to estimate the effects of lyophilized aqueous extract of flaxseed shell (AEF) and evaporated ethanolic extract of flaxseed shell (EEF), we studied their DPPH, ABTS, DMPD and O 2•-scavenging effects. 3+ reducing ability, and Fe 2+ chelating activity. Also, α-tocopherol, BHA, trolox, and BHT were used as positive controls. The results clearly AEF and EEF demonstrated effective antioxidant activity. The quantity of p-hydroxybenzoic, vanillin, p-coumaric acid, ascorbic acid, ferulic acid, and ellagic acid were investigated by LC-MS/MS. The present study will introduce a novelty for further studies on the antioxidant effects of AEF and EEF.

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“…+ scavenging ability DMPD + scavenging ability of P-Gum was performed according to Fogliano et al 47 and reported previously 48 . The scavenging capability of ABTS + radical of the sample was monitored in spectrophotometer at 505 nm.…”

Section: Measurement Of Dmpdmentioning

confidence: 99%

Pistachio (Pistacia veraL.) Gum: a potent inhibitor of reactive oxygen species

Şehitoğlu

Han

Kalın

et al. 2014

Journal of Enzyme Inhibition and Medicinal Chemistry

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Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst. and kit

Cited by 71 publications

References 23 publications

A comparative study on the antioxidant effects of hesperidin and ellagic acid against skeletal muscle ischemia/reperfusion injury

A comparative study on the antioxidant effects of hesperidin and ellagic acid against skeletal muscle ischemia/reperfusion injury

Antioxidant Activity of Flaxseed (Linum usitatissimum L.) shell and Analysis of Its Polyphenol Contents by LC-MS/MS

Pistachio (Pistacia veraL.) Gum: a potent inhibitor of reactive oxygen species

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