Appearance of hyperostosis frontalis interna in some osteoarcheological series from Hungary

Hajdu, Tamás; Fóthi, Erzsébet; Bernert, Zs.; Molnár, Erika; Lovász, Gabriella; ̋vári, I. Ko; Köhler, Kitti; Marcsik, Antónia

doi:10.1016/j.jchb.2008.07.004

Cited by 22 publications

(22 citation statements)

References 21 publications

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“…The very existence of the syndrome is even questioned by some experts, who claim that the conditions involved may occur independently in elderly women (2,16). The exact etiology of HFI and MSM syndrome remains unclear; the most interesting theories relate to estrogen dysfunction, obesity and leptin dysfunction, and genetics (17)(18)(19).…”

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confidence: 99%

Full Penetrance of Morgagni-Stewart-Morel Syndrome in a 75-Year-Old Woman: Case Report and Review of the Literature

Attanasio

Granziera

Giantin

et al. 2013

The Journal of Clinical Endocrinology & Metabolism

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A case of full penetrance of Morgagni-Stewart-Morel syndrome is reported, presenting many of the clinical features described in the literature. Metabolic and endocrine dysfunctions should be interpreted not only as isolated components of the syndrome, but also as the reason behind its pathogenesis. Endocrine or nutritional disorders may have led to an altered bone metabolism with frontal bone apposition. On the other hand, the severity of our patient's neurological and psychiatric symptoms correlates well with the severity of her hyperostosis frontalis interna and the cortical atrophy.

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confidence: 99%

Full Penetrance of Morgagni-Stewart-Morel Syndrome in a 75-Year-Old Woman: Case Report and Review of the Literature

Attanasio

Granziera

Giantin

et al. 2013

The Journal of Clinical Endocrinology & Metabolism

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“…However, in certain case presentations or in many case studies, it is revealed that when the internal surface osseous thickening is observed, it is situated either on the focal point or on the wide area it is covered by (6,13,14). On the other hand, changes observed in the ISFB with increased osseous thickening in the process of time were related to the density, shape and agglomeration in larger formations (8,10,19).…”

Section: Introductionmentioning

confidence: 96%

“…Many researchers have studied on the shape of the osseous thickening so far (6,8,10,13,14,19). In these studies, a variety of factors have been examined but the presence and incidence of osseous thickening in the ISFB were largely associated with hormonal disturbances such as pregnancy osteophytes, acromegaly, Paget's disease, osteoid osteoma, lentiasis ossea or senile hyperostosis (7,12,25).…”

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confidence: 99%

“…In these studies, a variety of factors have been examined but the presence and incidence of osseous thickening in the ISFB were largely associated with hormonal disturbances such as pregnancy osteophytes, acromegaly, Paget's disease, osteoid osteoma, lentiasis ossea or senile hyperostosis (7,12,25). The osseous thickening areas of the ISFB were located in the groove of the sagittal sinus (sagittal sulcus) and groove of the middle meningeal artery (sulci arteriosi) (6,10,23). Macroscopic as well as microscopic analysis of the osseous thickening areas of the ISFB have been applied to a few cases (8).…”

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confidence: 99%

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Increased osseous thickening of the inner surface of the frontal bone

Gövsa

Özer²,

Pınar³

et al. 2013

Turkish Neurosurgery

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AIm: Increased thickening of the internal surface of the frontal bone (ISFB) was investigated, regarding possible pressure application to the brain tissue and the changes in bone marrow structure. mATERIAl and mEThods: Morphological analysis of the ISFB was carried out in a total of 300 adult skulls.REsulTs: Type A, defined as normal appearance, has been detected in 243 cranium. In 57 cranium (19%), increased osseous thickening cases with different appearance were observed. The most frequent examples of osseous thickening were present in nodular types (Types B, C) and diffuse types (Types D, E), (29.8%). In fact, an irregular osseous thickening, which is in the form of plaques, was situated on both sides of the origin of sagittal sulcus. Types B and C were seen as small isolated nodules on the ISFB. In the histological analysis of ISFB, it is determined that the endocranium, normally present in a compact bone structure, changed its lamellar and had a nonwoven immature bone structure, in the areas with the characteristic of increased osseous thickening. The thickening of the diploe gap and increasing lamellar bone tissue in the endocranium revealed an increase in vascularization. CoNClusIoN:The nodular and widespread form of increased osseous thickening could apply pressure on to dura mater and the brain tissue.

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“…It is seldom found in males, but it is a common phenomenon among post-menopausal females in modern societies [1]. The etiology of HFI is uncertain: it may be due to an unknown genetic predisposition, a common environmental exposure, or special metabolic diseases [2]. Endocrine disturbances, aging, and dietary factors are also listed among the causes of HFI.…”

Section: Introductionmentioning

confidence: 99%

Hyperostosis frontalis interna: An Egyptian case referred to the second dynasty (2890–2650BC) from Tarkhan-Egypt

Shahin

Alhoseiny

Aldali

2014

The Egyptian Rheumatologist

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Aim of the work and case presentation: This article is to present the evidence of hyperostosis frontalis interna (HFI) in a young adult male, approximately (25-26) years old, recovered from a second dynasty site (2890-2650 BC) at Tarkhan in the south of Dahshur-Egypt.HFI is rare in historic populations. It is most commonly found among females with prolonged estrogen stimulation. Males with hormonal disturbances like primary hypogonadism were found to manifest with HFI.Conclusion: This study is a further contribution to the case history of HFI in osteoarcheological studies. Further researches are recommended to have an overview on such an old disease in Egypt.

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Appearance of hyperostosis frontalis interna in some osteoarcheological series from Hungary

Cited by 22 publications

References 21 publications

Full Penetrance of Morgagni-Stewart-Morel Syndrome in a 75-Year-Old Woman: Case Report and Review of the Literature

Full Penetrance of Morgagni-Stewart-Morel Syndrome in a 75-Year-Old Woman: Case Report and Review of the Literature

Increased osseous thickening of the inner surface of the frontal bone

Hyperostosis frontalis interna: An Egyptian case referred to the second dynasty (2890–2650BC) from Tarkhan-Egypt

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