Appendiceal Neoplasms

Spanos, Constantine P.; Kaiser, Andreas M.

doi:10.1007/978-3-319-25970-3_37

Cited by 6 publications

(15 citation statements)

References 51 publications

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“…On the other hand, epithelial tumors of the appendix represent only 0.1% of epithelial malignancies of the colon and rectum. They are frequently diagnosed in the seventh decade of life and are also more common in females [7][8][9].…”

Section: Epidemiologymentioning

confidence: 99%

“…The appendix has only one luminal communication with the colon and that is why an occlusion can end in appendicitis. For this reason, the appendiceal neoplasms usually present clinically as appendicitis, however, less than 50% of these tumors are recognized during the surgery [8].…”

Section: Pathologymentioning

confidence: 99%

“…Epithelial cells have basally oriented and small nuclei that are quite uniform, discreet nucleoli and rare mitoses. The cytoplasm frequently comprises abundant mucin resulting in low nuclear to cytoplasmic ratios [8,16].…”

Section: Mucinousmentioning

confidence: 99%

“…Microscopic inspection shows malignant glandular epithelial cells in strips, clusters, and complex proliferations. High grade dysplasia features cribriform growth, loss of nuclear polarity, enlarged and prominent nucleoli and numerous or atypical mitotic figures [8,[16][17]. It should be mentioned that if HAMN is identified, great care should be taken to exclude the presence of associated invasive adenocarcinoma [18].…”

Section: Mucinousmentioning

confidence: 99%

“…With these numbers, it is reasonably that a percentage of these specimens will show unexpected neoplastic pathology. Most of the neoplasms of the appendix are discovered incidentally in the pathological analysis; on the other hand, some can be identified intraoperatively [8].…”

Section: Introductionmentioning

confidence: 99%

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Appendiceal Neoplasms: Diagnosis, Management and Follow-up

Pereira

Martins

2021

SciMed. J.

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Appendicectomy is one of the most performed surgical procedures. Neoplasms of the appendix are identified in approximately 1% of appendiceal specimens, and the incidence seems to be rising. The aim of this review was to summarize the current data on these neoplasms, focusing on the recent classification, clinical manifestations, management, and follow-up of such patients, which remain under debate. A literature search was performed using the database PubMed. The keywords used were related to appendiceal neoplasms, mucocele, pseudomyxoma peritonei and treatment. Records without abstracts, case reports, opinion articles and experimental studies were excluded. The appendix tumors can be classified between epithelial or nonepithelial. The epithelial variant is composed by mucinous neoplasms, nonmucinous adenocarcinoma, and signet ring cell tumors; instead, neuroendocrine tumors, lymphoma, and sarcoma are included in nonepithelial neoplasia. Goblet cell carcinoids share characteristics of both epithelial and nonepithelial tumors. The clinical presentation can be variable and the algorithm for evaluation and treatment is complex. Treatment is based on stage and histology. Our intention is to clarify some questions and help the surgeon in operative decisions, treatment strategies, and patient counseling. Doi: 10.28991/SciMedJ-2021-0303-9 Full Text: PDF

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Section: Epidemiologymentioning

confidence: 99%

Section: Pathologymentioning

confidence: 99%

Section: Mucinousmentioning

confidence: 99%

Section: Mucinousmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Appendiceal Neoplasms: Diagnosis, Management and Follow-up

Pereira

Martins

2021

SciMed. J.

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Appendiceal cancer masked as inflammatory appendicitis in the elderly, not an uncommon presentation (Surveillance Epidemiology and End Results (SEER)‐Medicare Analysis)

Siddharthan

Byrne

Dewey

et al. 2019

Journal of Surgical Oncology

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Background: The misdiagnosis of appendiceal cancer as inflammatory appendicitis is becoming of greater clinical concern because of the rise of nonoperative management especially in the elder population. To quantify this rate of misdiagnosis, we retrospectively reviewed SEER-Medicare data.Methods: The SEER-Medicare database was reviewed from 2000 to 2014. We identified patients older than 65 years old who were diagnosed with appendiceal cancer and then cross-referenced them for a diagnosis of inflammatory appendicitis.Demographic data and oncologic stage were collected.Results: Our results showed that 28.6% of appendiceal cancer patients received an incorrect initial diagnosis of inflammatory appendicitis. Patients older than 75 years of

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Appendectomy (Open, Laparoscopic)

Zelhart

Kaiser

2022

Chassin's Operative Strategy in General Surgery

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Appendiceal Neoplasms

Cited by 6 publications

References 51 publications

Appendiceal Neoplasms: Diagnosis, Management and Follow-up

Appendiceal Neoplasms: Diagnosis, Management and Follow-up

Appendiceal cancer masked as inflammatory appendicitis in the elderly, not an uncommon presentation (Surveillance Epidemiology and End Results (SEER)‐Medicare Analysis)

Appendectomy (Open, Laparoscopic)

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