Applicability of the i/o-characters to a quantitative description of bioconcentration of organic chemicals in fish

Saito, Shoji; Tanoue, Akira; Matsuo, Masaru

doi:10.1016/0045-6535(92)90569-d

Cited by 20 publications

(3 citation statements)

References 2 publications

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“…RDDTs was the most abundant pollutant followed by the cyclodienes (trans-nonachlor and isodrin). HCB, an important by-product in PCB synthesis, was determined in very low levels due to reduced use and its lower bioaccumulation factor (Saito et al 1992). The levels of c-HCH in all samples were of the order of sub-ppb and even below 13,2000).…”

Section: Resultsmentioning

confidence: 99%

Organochlorine Pesticide Levels in Ensis siliqua (Linnaeus, 1758) from Ría de Vigo, Galicia (N.W. Spain): Influence of Season, Condition Index and Lipid Content

Carro¹,

Garcı́a²,

María³

et al. 2012

Bull Environ Contam Toxicol

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Levels of organochlorine pesticides (OCPs), including ΣDDTs, γ-HCH, HCB, aldrin, isodrin, trans-nonachlor, heptachlor and dieldrin, were determined in the razor clam, Ensis siliqua, collected monthly from February 2003 to April 2004 from the Islas Cíes in Ría de Vigo (Galicia, Spain). The sum of DDTs ranged from 2.17 to 26.9 ng g(-1) dry weight (dw). Principal component analysis showed seasonal trends in the levels of some OCPs (γ-HCH and dieldrin). Pearson correlations (p < 0.05) were observed between OCP levels and the biometric parameters of condition index and body lipids.

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Section: Resultsmentioning

confidence: 99%

Organochlorine Pesticide Levels in Ensis siliqua (Linnaeus, 1758) from Ría de Vigo, Galicia (N.W. Spain): Influence of Season, Condition Index and Lipid Content

Carro¹,

Garcı́a²,

María³

et al. 2012

Bull Environ Contam Toxicol

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“…Tilapia, as well as other aquatic organisms, appear concurrently or sequentially to be exposed to a wide array of chemicals from various sources. It has been found that most of the oestrogenic chemicals are lipophilic and hydrophobic and, hence, have a strong tendency to bioconcentrate in aquatic organisms, both plants and animals (Saito et al, 1992;Ahel et al, 1993). The use of an appropriate anti-phthalic ester antibody enables the detection of phthalate esters and the monitoring of their bioaccumulation within specific organ tissues of fishes.…”

Section: Discussionmentioning

confidence: 99%

Immnunohistochemical detection of phthalate esters in the alimentary canal of Tilapia spp.

Menghi

Sabbieti

Menghi

et al. 2002

Journal of Fish Biology

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An examination of the occurrence and distribution of phthalate esters in the alimentary canal of a polyhybrid of Tilapia gave evidence of different and selective patterns of distribution in the organ tissues: the phthalate esters were shown to be concentrated in the stomach and anterior intestine. The restricted distribution of phthalate esters can have implications for the physiology of the digestive system. The phthalates, stored in the oxyntic cells of the gastric tubular glands, probably interfere with the digestive process. The strategic location of the enterocytes in the anterior intestine implies that they can hamper the reabsorption of digestion products. The endocrine disrupting effects known for these chemicals are probably related to the absorption of them via the alimentary canal.

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“…The possibility of adverse health effects of endocrine disruption has received considerable public attention (3,4). As many pollutants released into the environment eventually reach bodies of water, they are concentrated in the tissues of aquatic organisms including fish (5). The use of fish is a popular approach to monitor and assess risks of exposure to chemicals in aquatic environments (6)(7)(8), as the fish endocrine system shares many similarities with those of higher vertebrates including humans (9).…”

Section: Introductionmentioning

confidence: 99%

Development of Estrogen-Responsive Transgenic Medaka for Environmental Monitoring of Endocrine Disrupters

Zeng

Shan

Tong

et al. 2005

Environ. Sci. Technol.

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To develop a transgenic fish system to monitor environmental pollution, we generated a mvtg1:gfp transgenic medaka line, in which the gfp reporter gene was under the control of medaka vitellogenin1 (mvtg1) gene promoter. In this transgenic line, GFP was exclusively expressed in the liver of the mature adult female. Male and juvenile transgenic fish did not express GFP but could be induced to express GFP in the liver after exposure to 17-beta-estradiol (E2). Concurrent accumulation of mvtg1 and gfp mRNAs was observed during both development and estrogen treatment, indicating that the gfp transgene was faithfully expressed under the mvtg1 promoter. Dose- and time-dependent induction of GFP expression by E2 was investigated in male transgenic fish. The lowest-observed-effect concentration (LOEC) of E2 to induce GFP expression was 0.5 microg/L by observation of live fish and 0.05-0.1 microg/L by observation of dissection-exposed liver in a 30 day exposure experiment. GFP expression was observed within 36 h after treatment in high concentrations of E2 (5 microg/L), and it took longer to detect GFP expression under lower concentrations of E2. By removal and readdition of E2, we demonstrated that GFP expression was repeatedly induced. Finally, we also demonstrated that GFP expression could be induced by other estrogenic compounds, including 17-alpha-ethynylestradiol (EE2, 0.05 microg/L), diethylstibestrol (DES, 5 microg/L), estriol (10 microg/ L), and bisphenol A (BPA, 1 mg/L), but not by weak estrogenic chemicals such as nonylphenol (NP, up to 1 mg/ L) and methoxychlor (MXC, up to 20 microg/L). Our experiments indicated the broad application of the transgenic line to monitor a wide range of estrogenic chemicals.

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Applicability of the i/o-characters to a quantitative description of bioconcentration of organic chemicals in fish

Cited by 20 publications

References 2 publications

Organochlorine Pesticide Levels in Ensis siliqua (Linnaeus, 1758) from Ría de Vigo, Galicia (N.W. Spain): Influence of Season, Condition Index and Lipid Content

Organochlorine Pesticide Levels in Ensis siliqua (Linnaeus, 1758) from Ría de Vigo, Galicia (N.W. Spain): Influence of Season, Condition Index and Lipid Content

Immnunohistochemical detection of phthalate esters in the alimentary canal of Tilapia spp.

Development of Estrogen-Responsive Transgenic Medaka for Environmental Monitoring of Endocrine Disrupters

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