Application and comparison of different criteria used for the diagnosis of type III hyperlipoproteinemia.

Laboratory-Based Assessment of Plasma Lipids and Lipopoteins for the Classification of Familial Hypercholesterolemic and Hypertriglyceridemic States

“…For phenotyping of FD, electrophoretic detection of the typical b-VLDL has been exchanged for a method based on the magnitude of the VLDL-cholesterol/ plasma triglyceride ratio or the VLDL-cholesterol/ VLDL-triglyceride ratio, determined by ultracentifugal analysis. 30 If the lipids are expressed in millimoles per liter, values of over 0.69 and over 0.95 were diagnostic for FD in combination with increased plasma lipid value for both ratios, respectively. 30 Patients with the apo-E3/ 2 and apo-E4/2 phenotypes (Fig.…”

“…30 If the lipids are expressed in millimoles per liter, values of over 0.69 and over 0.95 were diagnostic for FD in combination with increased plasma lipid value for both ratios, respectively. 30 Patients with the apo-E3/ 2 and apo-E4/2 phenotypes (Fig. 1) may sometimes have so many remnants that the cut-off value for the diagnosis of FD can also be reached here.…”