Application-driven multi-layered particles – The role of polymers in the architectural design of particles

Saha, Sampa; Loo, Say Chye Joachim

doi:10.1016/j.polymer.2015.06.033

Cited by 11 publications

(5 citation statements)

References 96 publications

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“…Magnetic particles are also applicable in the microscopic manipulation of nano- and micro-sized objects [ 5 ]. Applications of magnetic particles ranging from catalysis to drug delivery and remediation are only limited by their biocompatibility and immunogenicity, both of which can be controlled by proper layering and coating of particles ( Figure 1 ) [ 6 ]. To shed some light on the rapid developments in this field and the future prospects, it is important to deal with the challenges associated with the processes of design, synthesis and characterization.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Nanoparticles: From Design and Synthesis to Real World Applications

et al. 2017

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The increasing number of scientific publications focusing on magnetic materials indicates growing interest in the broader scientific community. Substantial progress was made in the synthesis of magnetic materials of desired size, morphology, chemical composition, and surface chemistry. Physical and chemical stability of magnetic materials is acquired by the coating. Moreover, surface layers of polymers, silica, biomolecules, etc. can be designed to obtain affinity to target molecules. The combination of the ability to respond to the external magnetic field and the rich possibilities of coatings makes magnetic materials universal tool for magnetic separations of small molecules, biomolecules and cells. In the biomedical field, magnetic particles and magnetic composites are utilized as the drug carriers, as contrast agents for magnetic resonance imaging (MRI), and in magnetic hyperthermia. However, the multifunctional magnetic particles enabling the diagnosis and therapy at the same time are emerging. The presented review article summarizes the findings regarding the design and synthesis of magnetic materials focused on biomedical applications. We highlight the utilization of magnetic materials in separation/preconcentration of various molecules and cells, and their use in diagnosis and therapy.

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Section: Introductionmentioning

confidence: 99%

Magnetic Nanoparticles: From Design and Synthesis to Real World Applications

et al. 2017

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“…Therefore, multilayered particulate systems can provide an attractive and robust approach to solve many problems associated with active (pharmaceutical or packaging) delivery by manipulating several particle parameters such as nature of polymer (polymer molecular weight, crystallinity, degradability, etc. ), layer thickness, number of layers and structural configurations, and so forth . Lee et al .…”

Section: Introductionmentioning

confidence: 99%

New insight into the mechanism of formation of dual actives loaded multilayered polymeric particles and their application in food preservation

Biswal¹,

Saha²

2019

J of Applied Polymer Sci

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This study provides an insight about the mechanism of formation of tri‐layered (instead of bilayers) particles originated from two biodegradable polymers by emulsion solvent evaporation method. It was also demonstrated how layer configurations of tri‐layered particles composed of poly(l‐lactide) (PLLA) and poly(d,l‐lactide‐co‐glycolide) (PLGA), can be changed from kinetically trapped to thermodynamically favorable structures (dictated by spreading coefficient theory) by tweaking several solution parameters. Layer switching, core, and shell thickness manipulation can also be achieved. Interestingly, among the various configurations, tri‐layered particles made with PLGA of intermediate viscosity and PLLA of high viscosity were found to provide controlled and sustainable release profiles for dual actives such as antibacterial (benzoic acid) and antioxidant (tocopherol) with appreciably high release rates. The dual activity of these particles was tested by incorporating them in chicken broth medium and found to provide excellent antibacterial as well as antioxidant activity for extended period of time (>20 days). © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 48009.

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“…In recent years, the fabrication of nanomaterials has gained enormous importance in multiple fields of engineering and sciences, such as analytical chemistry, biosensing, and nanomedicines. , The conditions of the experiments may alter their shape, size, and morphology. , Nanoparticles are applied for cancer treatment, drug delivery and remediation, molecular imaging, etc. In nanomaterial science, spinels have garnered much attention due to their physical, chemical, and magnetic properties as well as thermal stability .…”

Section: Introductionmentioning

confidence: 99%

“… 2 , 3 The conditions of the experiments may alter their shape, size, and morphology. 4 , 5 Nanoparticles are applied for cancer treatment, 6 drug delivery and remediation, 7 molecular imaging, 8 etc. In nanomaterial science, 9 spinels have garnered much attention due to their physical, chemical, and magnetic properties as well as thermal stability.…”

Section: Introductionmentioning

confidence: 99%

Tuning the Magnetic Behavior of Zinc Ferrite via Cobalt Substitution: A Structural Analysis

Hussain,

Mehmood,

Ali

et al. 2024

ACS Omega

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Cobalt-doped zinc ferrite is a contemporary material with significant structural and magnetic characteristics. Our study explores the magnetic properties of cobalt-substituted zinc ferrite (Zn x Co 1−x Fe 2 O 4 ), synthesized via a simple sol−gel method. By varying the cobalt ratio from 0 to 0.5, we found that zinc substitution impacts both the magnetization and lattice parameters. FTIR analysis suggested the presence of functional groups, particularly depicting an M−O stretching band, within octahedral and tetrahedral clusters. X-ray diffraction analysis confirmed the phase purity and cubic structure. The synthesized materials exhibited an average particle size of 24−75 nm. Scanning electron microscopy revealed the morphological properties, confirming the formation of truncated octahedral particles. In order to determine the stability, mass loss (%), and thermal behavior, a thermal analysis (thermogravimetric analysis (TGA)/differential thermal analysis (DTA)) was performed. The magnetic properties of the synthesized ferrites were confirmed via a vibrating sample magnetometer (VSM). Finally, the highest saturated magnetization and lowest coercivity values were observed with higher concentrations of the cobalt dopant substituting zinc. The synthesized nanomaterials have good stability as compared to other such materials and can be used for magnetization in the near future.

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Application-driven multi-layered particles – The role of polymers in the architectural design of particles

Cited by 11 publications

References 96 publications

Magnetic Nanoparticles: From Design and Synthesis to Real World Applications

Magnetic Nanoparticles: From Design and Synthesis to Real World Applications

New insight into the mechanism of formation of dual actives loaded multilayered polymeric particles and their application in food preservation

Tuning the Magnetic Behavior of Zinc Ferrite via Cobalt Substitution: A Structural Analysis

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