Application of Absorbancy Ratios to the Analysis of Pharmaceuticals I

Mixed Hydrotropy Solubilization Approach for Quantitative Estimation of Eprosartan Mesylate and Hydrochlorthiazide by UV Spectrophotometer

“…The concentration of the individual components were calculated by using the following equations; Cx = Qm-Qy/Qx-Qy)×A 1 /ax 1 (Eqn.3), Cy = Qm-Qy/QyQx)×A 1 /ax 1 (Eqn.4) where Qm = A 2 /A 1 , A 1 is absorbance of sample at isoabsorptive point, A 2 is absorbance of sample at λ max of one of the two components. ax 1 and ax 2 represent absorptivities of EPS at λ 1 and λ 2 and ay 1 and ay 2 denote absorptivities of HCZ at λ 1 and λ 2 respectively; Cx and Cy be the concentration of EPS and HCZ respectively [19,20].…”

Application of Absorbancy Ratios to the Analysis of Pharmaceuticals III

“…1. These characteristics indicated that binary mixtures containing phenobarbital and either amiiiophylline or theophylline could be analyzed by applying the principles described by Pernarowski, Knevel, and Christian (8). The first criterion cited by these authors for the use of the absorbancy ratio technique was the presence of an isoabsorptive point when the spectra of the substances being analyzed are superimposed.…”

“…T h e terminology and symbology used in this paper shall be that suggested by Pernarowski, Knevel, and Christian (8). Thus, the term " Q value" is an abbreviation for "absorbancy ratio value."…”

“…The former value, on the basis of 19 determinations, was equal to 23.7 f 1.0 while the latter value, on the basis of 27 determinations, was found to be 23.6 f 0.1. The details associated with the location of isoabsorptive points are given elsewhere (8).…”

Simultaneous Spectrophotometric Determination of Estradiol Valerate and Cyproterone Acetate : Estradiol Valerat Ve Siproteron Asetat'in Bi̇r Arada Spektrofotometri̇k Tayi̇ni̇

“…Vierordt's method was proposed by Heilmeyer (13) and succesfully applied to binary mixtures (14)(15)(16). Absorbance ratio method was introduced by Pernarowski for simultaneous determination of binary and ternary drug combinations (17)(18)(19)(20)(21).…”