Application of antioxidative Maillard reaction products from histidine and glucose to sardine products.

Tanaka, Munehiko; Kuei, Chu-Han; Nagashima, Yuji; Taguchi, Takeshi

doi:10.2331/suisan.54.1409

Cited by 336 publications

(216 citation statements)

References 4 publications

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“…This is consistent with previous studies. 29,32 Metal ion chelating ability is important since it reduces the concentration of the transition metal. 33 Hence, chelating Fe 2+ , generation of hydroxyl radicals in the Fenton reaction may be attenuated and thus prevent possible damage of hydroxyl radicals to biomolecules.…”

Section: Discussionmentioning

confidence: 99%

Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme

Ojo¹,

Ojo²,

Ajiboye³

et al. 2018

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Bryophyllum pinnatum (Lam.) Oken leaves are employed as food and as traditional medicines. This study investigates the antioxidant activity (reducing power, DPPH, ABTS, FRAP, H 2 O 2 scavenging ability and metal ion chelating), carbohydrate digesting enzymes activity and inhibitory activity of cholinergic enzyme of aqueous extract and fractions (n-hexane, ethyl acetate, n-butanol, residual aqueous fraction) of B. pinnatum leaves were investigated. Results showed that aqueous extract of B. pinnatum exhibited DPPH radical scavenging abilities, iron chelation, hydrogen peroxide scavenging abilities and reducing power (Fe 3+ -Fe 2+ ). B. pinnatum aqueous extract also had considerably α-amylase and α-glucosidase inhibitory activities with IC 50 values 149.20 ± 14.44 µg/mL and 126.15 ± 9.76 µg/mL respectively. Our findings indicated that ethyl acetate fraction contained a considerably higher (p < 0.05) amount of total phenolic, flavonoids, total antioxidant, FRAP, metal ion, ABTS and DPPH radical scavenging activity than other solvent fractions. Furthermore, the ethyl acetate fraction elicited a significantly higher (p < 0.05) inhibitory effects on α-glucosidase (IC 50 = 70.90 ± 1.23 μg/ml), α-amylase (IC 50 = 62.45 ± 1.22 μg/ml), acetylcholinesterase (AChE) (IC 50 = 66.75 µg/mL) and butyrylcholinesterase (BChE) (IC 50 = 62.97 µg/mL) activities than other fractions. Hence, B. pinnatum leaves were rich in biologically active components; thus, could be employed to formulate new plant-based pharmaceutical and nutraceutical drugs to improve human health.

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Section: Discussionmentioning

confidence: 99%

Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme

Ojo¹,

Ojo²,

Ajiboye³

et al. 2018

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“…was found remarkable and the reducing power of the extract was observed to rise as the concentration of the extract gradually increased. Earlier authors (Tanaka et al, 1988) have observed a direct correlation between antioxidant activity and reducing power of certain plant extracts. The reducing properties are generally associated with the presence of reductones (Duh et al, 1999), which have been shown to exert antioxidant action by breaking the free radical chain by donating a hydrogen atom (Gordon, 1990).…”

Section: Resultsmentioning

confidence: 99%

Antioxidant, cytotoxic and analgesic activities of the methanolic fruit extract of Terminalia chebula Retz.

et al. 2013

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The present study was aimed to investigate antioxidant, analgesic and cytotoxic activity of the methanolic extract of Terminalia chebula Retz. fruits. Antioxidant potential of the extract was evaluated by using nitric oxide scavenging assay, reducing power and total antioxidant capacity. The extract showed significant activities in all antioxidant assays compared to ascorbic acid in a dose dependent mode. In nitric oxide scavenging assay, the IC50 value of the extract was found to be 51.3 µg/mL while the IC50 value of ascorbic acid was 77.4 µg/mL. In addition to strong reducing power, total antioxidant activity of the extract was also found to increase in a dose dependent manner. The analgesic activity was evaluated using acetic acid-induced writhing test in mice. The extract, at a dose of 500 mg/kg, showed a maximum of 44.17 % inhibition (p < 0.05) of writhing reaction compared to the reference drug diclofenac-sodium (66.96 %). The extract also showed moderate cytotoxic activity in brine shrimp lethality bioassay and the LC50 value was found to be 97.36 µg/mL.DOI: http://dx.doi.org/10.3329/icpj.v3i1.17296 International Current Pharmaceutical Journal, December 2013, 3(1): 219-222

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“…Duh (1998) and Tanaka et al (1988) have observed a direct correlation between antioxidant activity and reducing power of certain plant extracts. The reducing properties are generally associated with the presence of reductones (Duh, 1998) which have been shown to exert antioxidant action by breaking the free radical chain by donating a hydrogen atom (Gordon, 1990).…”

Section: Reducing Powermentioning

confidence: 99%

In vitro antioxidant and antinociceptive potentialities of methanolic extract of Litsea glutinosa

Rumzhum

Rahman

Sharukh

et al. 2013

Bangladesh J. Sci. Ind. Res.

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The methanolic extract of Litsea glutinosa (Lauraceae) was evaluated for in vitro antioxidant activity by determination of hydrogen peroxide scavenging activity, total antioxidant capacity, assay of nitric oxide scavenging activity and reducing power test and in vivo antinociceptive effect in acetic acid induced writhing model in swiss albino mice. The results revealed the presence of pronounced antioxidant property as compared with ascorbic acid used as standard and a dose-dependent (250 and 500 mg/kg) analgesic effect. The antioxidant and antinociceptive properties observed seem to be in good accordance with the traditional uses of Litsea glutinosa.

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Application of antioxidative Maillard reaction products from histidine and glucose to sardine products.

Cited by 336 publications

References 4 publications

Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme

Inhibitory effect of Bryophyllum pinnatum (Lam.) Oken leaf extract and their fractions on α-amylase, α-glucosidase and cholinesterase enzyme

Antioxidant, cytotoxic and analgesic activities of the methanolic fruit extract of Terminalia chebula Retz.

In vitro antioxidant and antinociceptive potentialities of methanolic extract of Litsea glutinosa

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