Application of Chiral and Achiral Supercritical Fluid Chromatography in Pesticide Analysis: A Review

Deng, Huimin; Ji, Yuan; Tang, Sheng; Yang, Fei; Tang, Gangling; Shi, Hang; Lee, Hian Kee

doi:10.1016/j.chroma.2020.461684

Cited by 32 publications

(14 citation statements)

References 142 publications

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“…CSP is the critical parameter in optimizing the separation of enantiomers. 29 Herein, four chiral columns (CHIRALPAK AD-3, OD-3, OJ-3, and OZ-3) are used for chiral separation of diniconazole enantiomers with CO 2 /methanol (90:10, v/v). The polarity of methanol is higher than ethanol, acetonitrile, and isopropanol, and methanol reacts faster and more efficiently with supercritical CO 2 .…”

Section: Resultsmentioning

confidence: 99%

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Enantioselective Dissipation, Residue, and Risk Assessment of Diniconazole Enantiomers in Four Kinds of Fruits

Teng

Wang

et al. 2021

J. Agric. Food Chem.

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Chiral diniconazole is a widely used triazole fungicide, while its enantioselective behaviors in fruits have not been reported. In this article, the absolute configuration was confirmed. A fast supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS) method was developed for the chiral separation and enantioselective study of diniconazole in four kinds of fruits. The residual concentrations gradually decreased with time in four kinds of fruits after applying diniconazole. The dissipation half-lives of R-diniconazole and S-diniconazole were in the range of 5.3–7.9 and 2.5–7.1 days respectively, and S-diniconazole was degraded preferentially. The residue concentrations were lower than the EU’s MRL (0.01 mg/kg) on the 40th (harvest time), 30th, and 10th day in pear, jujube, and apple, respectively. But, in peach, residue concentrations were still higher than the MRL after 60 days and the ratio of R/S was 2.2. These results could be helpful for the reasonable use and risk assessment of chiral diniconazole.

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Section: Resultsmentioning

confidence: 99%

“…CSP is the critical parameter in optimizing the separation of enantiomers . Herein, four chiral columns (CHIRALPAK AD-3, OD-3, OJ-3, and OZ-3) are used for chiral separation of diniconazole enantiomers with CO 2 /methanol (90:10, v/v).…”

Section: Results and Discussionmentioning

confidence: 99%

Enantioselective Dissipation, Residue, and Risk Assessment of Diniconazole Enantiomers in Four Kinds of Fruits

Teng

Wang

et al. 2021

J. Agric. Food Chem.

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“…SFC presents a series of advantages over the chromatographic techniques described above, such as higher flow rates, shorter analysis times, lower organic solvent consumption, and lower waste production [36,37]. The use of high flow rates and faster separation without any adverse effect on separation efficiency is a consequence of the high diffusivity, high density, and low viscosity of supercritical fluids [47]. Another benefit of using SFC is that CO 2 can be easily evaporated, recycled, and reused under pressure.…”

Section: Supercritical Fluid Chromatography (Sfc)mentioning

confidence: 99%

Chiral Pesticides with Asymmetric Sulfur: Extraction, Separation, and Determination in Different Environmental Matrices

López-Cabeza

Francioso

2022

Separations

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Chiral pesticides with S atoms as asymmetric centers are gaining great importance in the search for new pesticides with new modes of action. As for the rest of the chiral pesticides, the determination of the stereoisomers separately has become crucial in the environmental risks assessment of these pesticides. Therefore, the development of suitable extraction and clean-up methods as well as efficient stereoselective analytical techniques for stereoisomers determination in environmental samples is essential. Currently, liquid/solid phase extraction, microextraction, and QuEChERS-based methods are most commonly used to obtain chiral pesticides from environmental samples. Gas, liquid, and supercritical fluid chromatography together with capillary electrophoresis techniques are the most important for the determination of the stereoisomers of chiral pesticides containing S atoms in its structure. In this study, all these techniques are briefly reviewed, and the advantages and disadvantages of each are discussed

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“…In addition, CO 2 is easily regenerated and has lower toxicity than conventional chromatographic solvents, thereby, providing a “more environmentally friendly” analytical method [ 3 ]. SFC can be used for chiral applications, especially on a preparative scale in the pharmaceutical industry [ 4 ]. At the same time, SFC is also used for the analysis of active ingredients in natural products [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

A Rapid and Sensitive Method for the Simultaneous Determination of Multipolar Compounds in Plant Tea by Supercritical Fluid Chromatography Coupled to Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry

Yue

Cao

2022

Foods

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In this study, matrix solid phase dispersion (MSPD) microextraction combined with supercritical fluid chromatography-ion mobility quadrupole time-of-flight mass spectrometry (SFC/IM-QTOF-MS) was used to analyze the multipolar compounds in plant tea. The parameters of stationary phase, mobile phase, make-up solution, temperature, and back pressure were optimized. The target analytes were gradient eluted in 8 min by supercritical CO2 on a Zorbax RX-SIL column. Collisional Cross Section (CCS) values for single and multiple fields were measured. A series of validation studies were carried out under the optimal conditions, and the linear relationship and reproducibility were good. The limits of detection were 1.4 (Scoparone (1))~70 (Naringenin (4)) ng/mL, and the limits of quantification were 4.7 (Scoparone (1))~241 (Naringenin (4)) ng/mL. The recoveries of most compounds ranged from 60.7% to 127%. As a consequence, the proposed method was used for the separation and quantitative analysis of active ingredients in caulis dendrobii.

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Application of Chiral and Achiral Supercritical Fluid Chromatography in Pesticide Analysis: A Review

Cited by 32 publications

References 142 publications

Enantioselective Dissipation, Residue, and Risk Assessment of Diniconazole Enantiomers in Four Kinds of Fruits

Enantioselective Dissipation, Residue, and Risk Assessment of Diniconazole Enantiomers in Four Kinds of Fruits

Chiral Pesticides with Asymmetric Sulfur: Extraction, Separation, and Determination in Different Environmental Matrices

A Rapid and Sensitive Method for the Simultaneous Determination of Multipolar Compounds in Plant Tea by Supercritical Fluid Chromatography Coupled to Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry

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