Application of Dendrimer/Gold Nanoparticles in Cancer Therapy: A Review

Nabavifard, Samaneh; Jalili, Shirin; Rahmati, Fereshteh; Vasseghian, Yasser; Ali, Gomaa A. M.; Agarwal, Shilpi; Gupta, Vinod Kumar

doi:10.1007/s10904-020-01705-4

Cited by 13 publications

(6 citation statements)

References 103 publications

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“…Natural or synthetic ways can synthesize NPs by two basic approaches, including various sub-preparation methods ( Figure 1 ). The first approach is called the "top to bottom" method, including breaking down bulk solid materials into smaller pieces by applying external energy from physical, chemical, and thermal techniques [ 11 ]. The second approach, called "from the bottom up, "brings together and combines atoms or molecules of gases or liquids.…”

Section: Metal Nanoparticles Synthesismentioning

confidence: 99%

The Recent Progress on Silver Nanoparticles: Synthesis and Electronic Applications

et al. 2021

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Nanoscience enables researchers to develop new and cost-effective nanomaterials for energy, healthcare, and medical applications. Silver nanoparticles (Ag NPs) are currently increasingly synthesized for their superior physicochemical and electronic properties. Good knowledge of these characteristics allows the development of applications in all sensitive and essential fields in the service of humans and the environment. This review aims to summarize the Ag NPs synthesis methods, properties, applications, and future challenges. Generally, Ag NPs can be synthesized using physical, chemical, and biological routes. Due to the great and increasing demand for metal and metal oxide nanoparticles, researchers have invented a new, environmentally friendly, inexpensive synthetic method that replaces other methods with many defects. Studies of Ag NPs have increased after clear and substantial support from governments to develop nanotechnology. Ag NPs are the most widely due to their various potent properties. Thus, this comprehensive review discusses the different synthesis procedures and electronic applications of Ag NPs.

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Section: Metal Nanoparticles Synthesismentioning

confidence: 99%

The Recent Progress on Silver Nanoparticles: Synthesis and Electronic Applications

et al. 2021

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“…Following that is the elaboration of the challenges and perspectives in the field, and this review will be ended with a summarized outlook and conclusion. As gold nanostructures for cancer treatment are extensively covered in the literature and many related reviews can be found [ 12 , 13 , 14 , 15 , 16 , 17 , 18 ], this review is limited to the following scope: (1) In terms of gold nanostructure shape, it only focuses on spherical gold nanoparticles, gold nanorods, and gold nanoclusters. (2) In terms of cancer type, it only targets high-incidence cancers such as breast cancer, liver cancer, skin cancer, and colon cancer.…”

Section: Introductionmentioning

confidence: 99%

Engineering Gold Nanostructures for Cancer Treatment: Spherical Nanoparticles, Nanorods, and Atomically Precise Nanoclusters

Wang¹,

Shen

et al. 2022

Nanomaterials

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Cancer is a major global health issue and is a leading cause of mortality. It has been documented that various conventional treatments can be enhanced by incorporation with nanomaterials. Thanks to their rich optical properties, excellent biocompatibility, and tunable chemical reactivities, gold nanostructures have been gaining more and more research attention for cancer treatment in recent decades. In this review, we first summarize the recent progress in employing three typical gold nanostructures, namely spherical Au nanoparticles, Au nanorods, and atomically precise Au nanoclusters, for cancer diagnostics and therapeutics. Following that, the challenges and the future perspectives of this field are discussed. Finally, a brief conclusion is summarized at the end.

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“…20 Targeted delivery systems can be divided into two types: delivery systems with a constant and dynamic composition. The first include targeted delivery systems based on polymers, 21 both artificial PAMAM, 22 PEI, 23 and polylactide 24 and natural ones, such as DNA and RNA. 25 Monomolecular micelles based on HBP 26 and dendrimers 27 can be considered a transitional stage between systems with a constant and dynamic composition.…”

Section: ■ Introductionmentioning

confidence: 99%

Doxorubicin-Loaded Hybrid Micelles Based on Carboxyl-Terminated Hyperbranched Polyester Polyol

Khannanov

Rossova

Улахович

et al. 2022

ACS Appl. Polym. Mater.

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The study of self-assembly processes in polymer solutions is the basis of a modern strategy for creating targeting systems for various substrates. In turn, the use of binary polymer/surfactant systems makes it possible to expand the range of polymers for creating drug delivery systems. This article describes the processes of formation of hybrid micelles based on carboxylterminal hyperbranched polyester polyol Boltorn H20[BH20-COOH] and surfactant Triton X-100[BH20-COOH/TX-100]. Using pH-metry, conductometry, dynamic light scattering (DLS), nanoparticle tracking analysis (NTA), and scanning electron microscopy (SEM), it was shown that at pH = 6.5, a monodisperse [BH20-COOH] associate with a hydrodynamic diameter D h = 79 ± 10 nm and hybrid micelles [BH20-COOH/TX-100] with D h = 114.3 ± 6 nm are formed. Both types of supramolecular associates are able to effectively encapsulate the anticancer drug doxorubicin. The viability analysis of HeLa and MCF-7 cells was performed in the presence of doxorubicin-loaded [BH20-COOH] and hybrid micelles [BH20-COOH/TX-100] in vitro.

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Application of Dendrimer/Gold Nanoparticles in Cancer Therapy: A Review

Cited by 13 publications

References 103 publications

The Recent Progress on Silver Nanoparticles: Synthesis and Electronic Applications

The Recent Progress on Silver Nanoparticles: Synthesis and Electronic Applications

Engineering Gold Nanostructures for Cancer Treatment: Spherical Nanoparticles, Nanorods, and Atomically Precise Nanoclusters

Doxorubicin-Loaded Hybrid Micelles Based on Carboxyl-Terminated Hyperbranched Polyester Polyol

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