1999
DOI: 10.1002/(sici)1096-9071(199903)57:3<313::aid-jmv16>3.0.co;2-a
|View full text |Cite
|
Sign up to set email alerts
|

Application of electronmicroscopy, enzyme immunoassay, and RT-PCR to monitor an outbreak of astrovirus type 1 in a paediatric bone marrow transplant unit

Abstract: During 1997, an extensive outbreak of astrovirus occurred in a unit where paediatric patients were being treated for leukaemias and inherited immune deficiency disorders. Prolonged shedding of virus for many months following infection was demonstrated in three patients who had undergone bone marrow transplantation. Comparison of reverse transcription-polymerase chain reaction (RT-PCR), enzyme immunoassay (EIA), and electronmicroscopy (EM) to monitor the outbreak showed that many subclinical infections, mainly … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

5
39
0
2

Year Published

2000
2000
2016
2016

Publication Types

Select...
6
3

Relationship

1
8

Authors

Journals

citations
Cited by 81 publications
(46 citation statements)
references
References 25 publications
5
39
0
2
Order By: Relevance
“…Fomites or inanimate surfaces play an important role in the institutional spread of HAstV infections (208,209,228). Fomites include serving and chopping utensils, and the ability of the virus to persist dried onto these surfaces long enough and in numbers high enough to represent a risk is a major public health issue.…”
Section: Epidemiology Hastv Transmissionmentioning
confidence: 99%
“…Fomites or inanimate surfaces play an important role in the institutional spread of HAstV infections (208,209,228). Fomites include serving and chopping utensils, and the ability of the virus to persist dried onto these surfaces long enough and in numbers high enough to represent a risk is a major public health issue.…”
Section: Epidemiology Hastv Transmissionmentioning
confidence: 99%
“…Outbreaks of astrovirus gastroenteritis have been reported for young adults, including military recruits (2), students, teachers (28), and children (25). Astrovirus and other gastroenteric virus infections can occur in immunocompromised children (5,30), such as those undergoing bone marrow transplantation (6,37), those with severe combined immunodeficiency (4), those with T-cell immunodeficiency in cartilage hair hypoplasia (10,36), or those with human immunodeficiency virus/AIDS (18).…”
Section: An Outbreak Of Astrovirus Gastroenteritis Occurred In the Prmentioning
confidence: 99%
“…[29][30][31][32][33][34][35][36][37][38][39] A policy of influenza vaccination for all staff and the prohibition of staff working in SCT units who have symptoms of viral upper respiratory infection is appropriate. Removal of staff may, however, not be possible due to lack of availability of trained and experienced colleagues.…”
Section: Discussionmentioning
confidence: 99%