Application of Encapsulation Strategies for Probiotics: From Individual Loading to Co-Encapsulation

Agriopoulou, Sofia; Tarapoulouzi, Maria; Varzakas, Theodoros; Jafari, Seid Mahdi

doi:10.3390/microorganisms11122896

Cited by 13 publications

(4 citation statements)

References 157 publications

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“…Since living cells of PRO strains must survive for an extended period and withstand the gastric environment and temperatures, various encapsulation techniques have been developed [38,48]. In encapsulation, a semipermeable membrane or matrix of a highly sensitive component is used [49].…”

Section: Encapsulation Of Probiotics In Monolayer Beads/carriers; Fun...mentioning

confidence: 99%

Encapsulation of piROBotics within Double/Multiple Layer Beads/Carriers: A Concise Review

Agriopoulou,

Smaoui,

Chaari

et al. 2024

Preprint

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An increased demand for natural products nowadays most specifically probiotics (PRO) is evident since it comes in conjunction with beneficial health effects for the consumers. In this regard, it is well known that encapsulation could affect positively the PRO's viability throughout food manufacturing and long-term storage. This paper aims to analyze and review various multilayer strategies for encapsulation of PRO. Double-layer encapsulation of PRO by electro-hydrodynamic atomization or electrospray technology has been reported along with layer-by-layer assembly and water-in-oil-in-water (W1/O/W2) double emulsions to produce multilayer PRO-loaded carriers. Finally, their applications in food products are presented. The resistance (cover material) and viability of (PRO) to mechanical damage, during gastrointestinal transit and shelf life of these trapping systems are also described. The PRO encapsulation in double and multiple-layer coatings combined with other technologies can be examined to increase the opportunities for new functional products with amended functionalities opening a novel horizon in food technology.

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Section: Encapsulation Of Probiotics In Monolayer Beads/carriers; Fun...mentioning

confidence: 99%

Encapsulation of piROBotics within Double/Multiple Layer Beads/Carriers: A Concise Review

Agriopoulou,

Smaoui,

Chaari

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Since living cells of PRO strains must survive for an extended period and withstand the gastric environment and temperatures, various encapsulation techniques have been developed [ 42 , 53 ]. In encapsulation, a semipermeable membrane or matrix of a highly sensitive component is used [ 54 ].…”

Section: Encapsulation Of Probiotics In Monolayer Beads/carriers—fund...mentioning

confidence: 99%

Encapsulation of Probiotics within Double/Multiple Layer Beads/Carriers: A Concise Review

Agriopoulou,

Smaoui,

Chaari

et al. 2024

Molecules

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An increased demand for natural products nowadays most specifically probiotics (PROs) is evident since it comes in conjunction with beneficial health effects for consumers. In this regard, it is well known that encapsulation could positively affect the PROs’ viability throughout food manufacturing and long-term storage. This paper aims to analyze and review various double/multilayer strategies for encapsulation of PROs. Double-layer encapsulation of PROs by electrohydrodynamic atomization or electrospraying technology has been reported along with layer-by-layer assembly and water-in-oil-in-water (W1/O/W2) double emulsions to produce multilayer PROs-loaded carriers. Finally, their applications in food products are presented. The resistance and viability of loaded PROs to mechanical damage, during gastrointestinal transit and shelf life of these trapping systems, are also described. The PROs encapsulation in double- and multiple-layer coatings combined with other technologies can be examined to increase the opportunities for new functional products with amended functionalities opening a novel horizon in food technology.

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“…Still, only a few of the numerous liposomal systems developed each year have received clinical approval. None of them incorporate active targeting [ 53 ].…”

Section: The Main Categories Of Commonly Used Nanopharmaceuticalsmentioning

confidence: 99%

Nanoformulations in Pharmaceutical and Biomedical Applications: Green Perspectives

Petrovic,

Bita,

Barbinta-Patrascu

2024

IJMS

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This study provides a brief discussion of the major nanopharmaceuticals formulations as well as the impact of nanotechnology on the future of pharmaceuticals. Effective and eco-friendly strategies of biofabrication are also highlighted. Modern approaches to designing pharmaceutical nanoformulations (e.g., 3D printing, Phyto-Nanotechnology, Biomimetics/Bioinspiration, etc.) are outlined. This paper discusses the need to use natural resources for the “green” design of new nanoformulations with therapeutic efficiency. Nanopharmaceuticals research is still in its early stages, and the preparation of nanomaterials must be carefully considered. Therefore, safety and long-term effects of pharmaceutical nanoformulations must not be overlooked. The testing of nanopharmaceuticals represents an essential point in their further applications. Vegetal scaffolds obtained by decellularizing plant leaves represent a valuable, bioinspired model for nanopharmaceutical testing that avoids using animals. Nanoformulations are critical in various fields, especially in pharmacy, medicine, agriculture, and material science, due to their unique properties and advantages over conventional formulations that allows improved solubility, bioavailability, targeted drug delivery, controlled release, and reduced toxicity. Nanopharmaceuticals have transitioned from experimental stages to being a vital component of clinical practice, significantly improving outcomes in medical fields for cancer treatment, infectious diseases, neurological disorders, personalized medicine, and advanced diagnostics. Here are the key points highlighting their importance. The significant challenges, opportunities, and future directions are mentioned in the final section.

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Application of Encapsulation Strategies for Probiotics: From Individual Loading to Co-Encapsulation

Cited by 13 publications

References 157 publications

Encapsulation of piROBotics within Double/Multiple Layer Beads/Carriers: A Concise Review

Encapsulation of piROBotics within Double/Multiple Layer Beads/Carriers: A Concise Review

Encapsulation of Probiotics within Double/Multiple Layer Beads/Carriers: A Concise Review

Nanoformulations in Pharmaceutical and Biomedical Applications: Green Perspectives

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