2006
DOI: 10.1016/j.bios.2005.04.003
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Application of europium(III) chelate-dyed nanoparticle labels in a competitive atrazine fluoroimmunoassay on an ITO waveguide

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Cited by 48 publications
(18 citation statements)
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“…Direct surface-readout removes the need for separate dissociation enhancement or substrate incubation step associated with conventional DELFIA [22] and ELISA methods in microtitration wells. Commercial europium(III) chelate-dyed polystyrene particles [112][113][114] have been recently utilized in lateral flow assays, in an optical waveguide-based immunosensor and in protein array on surface of nanoporous silicon [115]. Best reported assay performance, however, has been described with in-house prepared lanthanidechelate-labeled silica nanoparticles [48] due to incredibly low nonspecific binding.…”
Section: High Assay Sensitivitymentioning
confidence: 97%
“…Direct surface-readout removes the need for separate dissociation enhancement or substrate incubation step associated with conventional DELFIA [22] and ELISA methods in microtitration wells. Commercial europium(III) chelate-dyed polystyrene particles [112][113][114] have been recently utilized in lateral flow assays, in an optical waveguide-based immunosensor and in protein array on surface of nanoporous silicon [115]. Best reported assay performance, however, has been described with in-house prepared lanthanidechelate-labeled silica nanoparticles [48] due to incredibly low nonspecific binding.…”
Section: High Assay Sensitivitymentioning
confidence: 97%
“…As a semi-quantitative detection method, the ICG strip assay can be combined with ELISA to achieve the goal of on-site quantitative screening and serving as a AP alkaline phosphatase; h NC membrane: nitrocellulose membrane; i LOD limit of detection; j visual LOD was defined as the minimum concentration producing the disappearance of color on the test line or test spot complement to instrumental techniques. In addition, some studies on biosensors for the determination of atrazine have been reported [22][23][24][25]. Yang et al [26] have successfully applied aligned carbon nanotubes, one of the newest carbonbased materials, in the biosensor.…”
Section: Introductionmentioning
confidence: 98%
“…It is prone to leaching to groundwater and surface runoff from soils and sediments. Atrazine has been frequently detected as a contaminant in soils, surface water, and groundwater in many countries [3][4][5][6][7]. More importantly, AT is classified as a possible human carcinogen by the US Environmental Protection Agency, and it is a known endocrine disrupting substance posing a potential health risk to humans [8,9] and wildlife [10].…”
Section: Introductionmentioning
confidence: 99%