Application of laser ablation technique for removal of chemically inert organically modified silicate coatings

Metroke, Tammy L.; Stesikova, Elvira; Dou, Kai; Knobbe, Edward T.

doi:10.1016/s0300-9440(02)00195-9

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Alternatively, the second method makes use of an ultrafast laser characterized by ultrahigh peak power pulses, to introduce a spatially patterned macropore system by laser drilling into a silica/gelatin/ β-TCP sol-gel-derived monolith composite. According to the existing literature, although the technique has been previously utilized for the removal of organically modified silicate coatings [ 57 ], this is the first time that a complete perforation by laser micromachining of a sol-gel-processed hybrid polymer/ceramic monolith composite, is planned. Both the hole quality and maximum ablated depth are optimized by controlling the laser machining parameters for the selected solid target.…”

Section: Introductionmentioning

confidence: 99%

Robocasting and Laser Micromachining of Sol-Gel Derived 3D Silica/Gelatin/β-TCP Scaffolds for Bone Tissue Regeneration

Reyes-Peces

Félix

Martínez‐Vázquez

et al. 2022

Gels

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The design and synthesis of sol-gel silica-based hybrid materials and composites offer significant benefits to obtain innovative biomaterials with controlled porosity at the nanostructure level for applications in bone tissue engineering. In this work, the combination of robocasting with sol-gel ink of suitable viscosity prepared by mixing tetraethoxysilane (TEOS), gelatin and β-tricalcium phosphate (β-TCP) allowed for the manufacture of 3D scaffolds consisting of a 3D square mesh of interpenetrating rods, with macropore size of 354.0 ± 17.0 μm, without the use of chemical additives at room temperature. The silica/gelatin/β-TCP system underwent irreversible gelation, and the resulting gels were also used to fabricate different 3D structures by means of an alternative scaffolding method, involving high-resolution laser micromachining by laser ablation. By this way, 3D scaffolds made of 2 mm thick rectangular prisms presenting a parallel macropore system drilled through the whole thickness and consisting of laser micromachined holes of 350.8 ± 16.6-micrometer diameter, whose centers were spaced 1312.0 ± 23.0 μm, were created. Both sol-gel based 3D scaffold configurations combined compressive strength in the range of 2–3 MPa and the biocompatibility of the hybrid material. In addition, the observed Si, Ca and P biodegradation provided a suitable microenvironment with significant focal adhesion development, maturation and also enhanced in vitro cell growth. In conclusion, this work successfully confirmed the feasibility of both strategies for the fabrication of new sol-gel-based hybrid scaffolds with osteoconductive properties.

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Section: Introductionmentioning

confidence: 99%