Application of Latent Class Analysis to Identify Subgroups of Children with Autism Spectrum Disorders who Benefit from Social Skills Training

Dekker, Vera; Nauta, Maaike; Timmerman, Marieke E.; Mulder, E.; Hoekstra, Pieter J.; Bildt, Annelies de

doi:10.1007/s10803-020-04678-y

Cited by 8 publications

(5 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Psychopathology-based subgroups also affect responses to intervention and should be carefully considered in the development of intervention guidelines, which are currently broad (i.e., non-specific to subpopulations), and future studies (Antshel et al, 2011;McBride et al, 2020;Dekker et al, 2021;Wickstrom et al, 2021). Finally, the findings of this study provide additional rationale to investigate the shared mechanisms of psychiatric and medical conditions.…”

Section: Discussionmentioning

confidence: 86%

“…For example, based on our study’s subgroups, when seeing a child with ASD and a combination of sleep disturbances, gastrointestinal disorders, and/or neurological disorders, a pediatrician may want to collaborate with a mental health provider, as this child might be at particularly high risk for externalizing problems, whereas a child with a NVIQ < 70 could be suspectable to internalizing problems, and a child with a NVIQ < 70, a sleep disturbance, and/or a gastrointestinal disorder may be vulnerable to both internalizing and externalizing problems. Psychopathology-based subgroups also affect responses to intervention and should be carefully considered in the development of intervention guidelines, which are currently broad (i.e., non-specific to subpopulations), and in future studies on how different subpopulations of children with ASD respond to interventions targeting core and associated symptoms (Antshel et al, 2011; McBride et al, 2020; Dekker et al, 2021; Wickstrom et al, 2021). For example, light therapy could be beneficial to children belonging to a “High Psychopathology” subgroup, who are at elevated risk for depression and sleep disturbances (Fritzsche et al, 2001).…”

Section: Discussionmentioning

confidence: 99%

“…For example, based on our study’s subgroups, when seeing an autistic child with a combination of internalizing and externalizing symptoms, a psychologist may want to collaborate with a physician to monitor for atypical sleep duration, gastrointestinal conditions, and/or neurological conditions. Psychiatric symptom-based subgroups also affect responses to intervention and should be carefully considered in the development of intervention guidelines, which are currently broad (i.e., non-specific to subpopulations), and in future studies on how different subpopulations of autistic children respond to interventions (Antshel et al, 2011; McBride et al, 2020; Dekker et al, 2021; Wickstrom et al, 2021). For example, light therapy could be beneficial to children belonging to a High Psychiatric Symptoms subgroup, who are at elevated risk for depression and atypical sleep duration (Fritzsche et al, 2001).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Subgrouping School-Aged Children on the Autism Spectrum Based on Co-Occurring Psychiatric Symptoms

Piergies¹,

Hirota²,

Monden

et al. 2021

Preprint

View full text Add to dashboard Cite

Background: Symptom heterogeneity within autism spectrum disorder (ASD) is compounded by co-occurring psychopathology. Considering that some psychiatric disorders present together more often than others, deriving subgroups of individuals with ASD based on co-occurring psychopathology could better our understanding of symptom patterns existing within this population. This study's purpose was to derive subgroups of school-aged children with ASD based on co-occurring psychopathology while controlling for age and sex and to examine correlates of subgroup membership. Method: Six latent class models were estimated with a sample from the Simons Simplex Collection (n = 2,092), using dichotomized categories (borderline/clinical versus normal range) from five of the DSM-Oriented Scales of the Child Behavior Checklist for Ages 6 to 18 as indicator variables. We evaluated the predictive value of intellectual disability and three groups of medical conditions (allergies/autoimmune disorders, gastrointestinal disorders, and neurological disorders) on subgroup membership using multinomial logistic regression. Results: Four subgroups emerged based on the combined presence/absence of psychiatric symptoms: "Low Psychopathology," "Externalizing Problems," "Internalizing Problems," and "High Psychopathology." Gastrointestinal disorders, the strongest predictor, was associated with increased odds of belonging to the "Externalizing Problems," "Internalizing Problems," and "High Psychopathology" subgroups over the "Low Psychopathology" subgroup, whereas intellectual disability was associated with decreased odds. Neurological disorders was also associated with increased odds of belonging to the "Internalizing Problems" and "High Psychopathology" subgroups. Conclusion: Patterns of psychopathology exist within school-aged children with ASD and are correlated with intellectual disability as well as specific medical conditions, providing guidance for clinical practice and etiology-driven research.

show abstract

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Subgrouping School-Aged Children on the Autism Spectrum Based on Co-Occurring Psychiatric Symptoms

Piergies¹,

Hirota²,

Monden

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…For example, based on our study's subgroups, when seeing an autistic child with a combination of internalizing and externalizing symptoms, a psychologist may want to collaborate with a physician to monitor for atypical sleep duration and/or gastrointestinal conditions. Psychiatric symptom-based subgroups also affect responses to intervention and should be carefully considered in the development of intervention guidelines, which are currently broad (i.e., non-specific to subpopulations), and in future studies on how different subpopulations of autistic children respond to interventions (Antshel et al, 2011;Dekker et al, 2021;McBride et al, 2020;Wickstrom et al, 2021). For example, light therapy could be beneficial to children belonging to a High Psychiatric Symptoms subgroup, who are at elevated risk for depression and atypical sleep duration (Fritzsche et al, 2001).…”

Section: Discussionmentioning

confidence: 99%

Subgrouping school-aged children on the autism spectrum based on co-occurring psychiatric symptoms

Piergies

Hirota

Monden

et al. 2022

Research in Autism Spectrum Disorders

View full text Add to dashboard Cite

“…Vera lives in Assen with Johan and their three children Leon (4 years), Bas (2 years), and Anne (0 years). Dekker, V., Nauta, M.H., Hoekstra, P.J., & de Bildt, A. (2021).…”

Section: Dankwoordmentioning

confidence: 99%

Effectiveness of Social Skills Training for children with autism spectrum disorder

Dekker¹

Self Cite

View full text Add to dashboard Cite

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is characterized by impairments in social communication and interaction and by the presence of restricted and repetitive patterns of behaviors, interests, or activities (American Psychiatric Association, 2013). The impairments in social communication and interaction result in limited socio-emotional reciprocity, ranging from not being able to initiate contact to initiating or responding to social contact in a way that is deviant and that may be inappropriate. Other impairments concern non-verbal communication (for example initiating and maintaining eye contact) and developing, maintaining, and understanding relationships (for example engaging in reciprocal conversations, emotion recognition, empathy, joint attention, and recognition of social cues; American Psychiatric Association, 2013).ASD is a heterogeneous disorder that manifests in many different ways. The expression of impairments differs between children and over time (Lord et al., 2020). Besides ASD, other disorders often co-occur in children with ASD, such as Attentiondeficit/hyperactivity Disorder (ADHD), anxiety, depression, and epilepsy. The current mean prevalence of ASD in the United States is approximately 1.5-2% in children aged 8 years (Maenner et al., 2020) and in Europe between 0.4% and 3.1% (Chiarotti & Venerosi, 2020). GeneralizationApart from the effects of SST in children with ASD on the specific social skills as learned during the training, a few other aspects should be considered when studying the effect of SST. One of these is the generalization of learned social-communicative skills in order to appropriately interact in daily life situations.Although generalization of learned social skills to situations beyond the training is an important assumption of SST, only few studies have investigated this generalization to different daily life situations (

show abstract

Application of Latent Class Analysis to Identify Subgroups of Children with Autism Spectrum Disorders who Benefit from Social Skills Training

Cited by 8 publications

References 31 publications

Subgrouping School-Aged Children on the Autism Spectrum Based on Co-Occurring Psychiatric Symptoms

Subgrouping School-Aged Children on the Autism Spectrum Based on Co-Occurring Psychiatric Symptoms

Subgrouping school-aged children on the autism spectrum based on co-occurring psychiatric symptoms

Effectiveness of Social Skills Training for children with autism spectrum disorder

Contact Info

Product

Resources

About