Application of Low Energy Proton Beam for Determination of Elemental Composition in Healthy and Pathological Tissues

The elemental composition of rabbit liver was determined by the PIXE and micro-PIXE methods. The mean concentrations of P, S, Cl, K, Fe, Cu, Zn, and Rb measured by both methods were similar. The latter method also allowed for localization of elements within lobule territory. It has been found that some elements are more prevalent in the veins (Cl, Fe) and others in the liver parenchyma (P, Cu, Zn). Moreover, Zn showed the characteristic intralobular distribution. Some methodological aspects of microbeam application to biological materials were also discussed.

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Distribution of elements in rabbit liver lobule

Cichocki

Gonsior

Glazur

et al. 1987

Biol Trace Elem Res

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The influence of target preparation and mode of irradiation on PIXE analysis of biological samples

Galuszka

Jarczyk

Rokita

et al. 1984

Nuclear Instruments and Methods in Physics Research Section B:

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Macro- and micro-PIXE analyses of biological and medical samples

Vis

Stap

Bos

1984

Nuclear Instruments and Methods in Physics Research Section B:

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Application of Low Energy Proton Beam for Determination of Elemental Composition in Healthy and Pathological Tissues

Cited by 7 publications

References 3 publications

Distribution of elements in rabbit liver lobule

Distribution of elements in rabbit liver lobule

The influence of target preparation and mode of irradiation on PIXE analysis of biological samples

Macro- and micro-PIXE analyses of biological and medical samples

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