2018
DOI: 10.1186/s12863-018-0647-2
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Application of novel and existing methods to identify genes with evidence of epigenetic association: results from GAW20

Abstract: BackgroundThe rise in popularity and accessibility of DNA methylation data to evaluate epigenetic associations with disease has led to numerous methodological questions. As part of GAW20, our working group of 8 research groups focused on gene searching methods.ResultsAlthough the methods were varied, we identified 3 main themes within our group. First, many groups tackled the question of how best to use pedigree information in downstream analyses, finding that (a) the use of kinship matrices is common practice… Show more

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