Application of Radar Techniques of Signal Processing for Ultra-High Resolution Electrocardiography

Zaichenko, Kirill V.; Kordyukova, Anna; Logachev, Evgeny; Luchkova, M. N.

doi:10.1007/s10527-021-10065-3

Cited by 13 publications

(1 citation statement)

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“…UHR ECG ensures registration and analysis of all meaningful changes of the electrical cardiac potentials using standard ECG electrodes. This is achieved by inclusion of maximally extended frequency and magnitude ranges [20]. In particular, UHR ECG is aiming to analyze electrical activity of the heart in the frequency range with the upper limit of 2000 Hz (Figure 1a).…”

Section: Registration Of Uhr Ecg and Signal Processingmentioning

confidence: 99%

Ultra-High-Resolution Electrocardiography Enables Earlier Detection of Transmural and Subendocardial Myocardial Ischemia Compared to Conventional Electrocardiography

Zaichenko,

Kordyukova,

Sonin

et al. 2023

Diagnostics

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The sensitivity of exercise ECG is marginally sufficient for the detection of mild reduction of coronary blood flow in patients with early coronary atherosclerosis. Here, we describe the application of a new technique of ECG registration/analysis—ultra-high-resolution ECG (UHR ECG)—for early detection of myocardial ischemia (MIS). The utility of UHR ECG vs. conventional ECG (C ECG) was tested in anesthetized rats and pigs. Transmural MIS was induced in rats by the ligation of the left coronary artery (CA). In pigs, subendocardial ischemia of a variable extent was produced by stepwise inflation of a balloon within the right CA, causing a 25–100% reduction of its lumen. In rats, a reduction in power spectral density (PSD) in the high-frequency (HF) channel of UHR ECG was registered at 60 s after ischemia (power 0.81 ± 0.14 vs. 1.25 ± 0.12 mW at baseline, p < 0.01). This was not accompanied by any ST segment elevation on C ECG. In pigs, PSD in the HF channel of UHR ECG was significantly decreased at a 25% reduction of CA lumen, while the ST segment on C ECG remained unchanged. In conclusion, UHR ECG enabled earlier detection of transmural MIS compared to C ECG. PSD in the HF channel of UHR ECG demonstrated greater sensitivity in the settings of subendocardial ischemia.

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Section: Registration Of Uhr Ecg and Signal Processingmentioning

confidence: 99%