Application of synchronous cyclic capillary electrophoresis: Isotopic and chiral separations

Zhao, Jinping; Jorgenson, James W.

doi:10.1002/(sici)1520-667x(1999)11:6<439::aid-mcs6>3.0.co;2-z

Cited by 13 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Keeping the ends of two capillaries together is one way to create an electrolytic connection between the inner lumen of the capillaries and the external environment , i.e. with the buffer in the reservoir.…”

Section: Theorymentioning

confidence: 99%

“…This was inspired by the pioneering work named synchronized cyclic capillary electrophoresis, demonstrated more than 20 years ago . Basically, the TCE mode presented here uses a real toroidal capillary (as a single piece) instead of segments of microchannels or segments of capillaries with the ends positioned opposite to each other . Therefore, it is not of cyclic nature because there is no band transfer from one capillary to another and because the programmable high voltage power supply of this proposal keeps the bands on a quasi continuous migration mode along the axial direction of the toroid during all the time (without pit‐stops).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Number of theoretical plates achievable by a toroidal capillary electrophoresis system

Kist

2017

J of Separation Science

View full text Add to dashboard Cite

The ability of a method and instrument to separate very similar compounds is related to the "plate number," a number indicating performance. The resolution between two neighboring peaks is proportional to the square root of the plate number. Currently available commercial capillary electrophoresis instruments easily reach plate numbers of a few million. In the present work, a capillary electrophoresis system with a toroidal platform is proposed and theoretically studied with the goal of extending the achievable plate number. In this new system, electrophoresis occurs in a nonstop continuous circulating mode within a closed loop capillary (toroid). Plate numbers upwards of one billion are theoretically predicted. This could resolve hundreds of unseparated mixtures of stereoisomers and other analytes that remain without a method for their analysis.

show abstract

Section: Theorymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Number of theoretical plates achievable by a toroidal capillary electrophoresis system

Kist

2017

J of Separation Science

View full text Add to dashboard Cite

show abstract

Recent progress in chiral separation principles in capillary electrophoresis

2000

View full text Add to dashboard Cite

This review summarizes recent developments in the field of chiral separations by electromigration techniques including capillary zone electrophoresis (CZE), capillary gel electrophoresis (CGE), isotachophoresis (ITP), electrokinetic chromatography (EKC), and capillary electrochromatography (CEC). This overview focuses on the development of new chiral selectors and the introduction of new techniques rather than applications of already established selectors and methods. The mechanisms of the different chiral separation principles are discussed.

show abstract

Toroidal Layout

2020

Open and Toroidal Electrophoresis

View full text Add to dashboard Cite

Application of synchronous cyclic capillary electrophoresis: Isotopic and chiral separations

Cited by 13 publications

References 37 publications

Number of theoretical plates achievable by a toroidal capillary electrophoresis system

Number of theoretical plates achievable by a toroidal capillary electrophoresis system

Recent progress in chiral separation principles in capillary electrophoresis

Toroidal Layout

Contact Info

Product

Resources

About