The micro-brewery business has been subjected to rapid growth within the last decade.Most brewers are facing expensive wastewater compliance bills and are seeking reliable on-site treatment methods. Anaerobic membrane bioreactor (AnMBR) treatment is favorable to the widely used upflow anaerobic sludge blanket (UASB) method. It offers high quality effluent free of solids, and has great stabilities under loading shocks. To date, there have been limited submerged AnMBR studies and none have been conducted on brewery wastewater. In this research, a state-of-the-art AnMBR laboratory scale system was used to investigate the performance and capability. The system was subjected to 230 days continuous operation with both synthetic and real brewery wastewater at organic loading rates (OLRs) ranging from 2 to 11.5 kg COD/m 3 /day. While the system demonstrated an excellent biological performance, the study found that the major limitation of AnMBR was the membrane fouling, which increased with the OLR and soluble microbial products (SMPs) in the mixed liquor.iii ACKNOWLEDGEMENTS