Ground-based optical transmitter and receiver systems designed for active imaging, active tracking and laser ranging of satellites in Earth orbit are very sensitive to physical conditions limiting the radiometric returns for achieving these measurements. The initial design of these systems is often based on simple radiometric scaling laws that provide estimates of average radiometric returns and are derived from experimental data or from more complex theoretical calculations. While these laws are quite useful, it is often easy to lose sight of the initial assumptions made in their formulation, and hence, the limits of their accuracy for designing certain systems. The objective of this paper is to review some of the commonly used radiometric scaling laws for active systems and to establish guidelines for their use based on comparisons of their predictions with results from detailed wave-optics simulations for different system design requirements and physical conditions. The combined effects of laser and transmitter beam parameters, wave-front aberrations, atmospheric turbulence, and satellite optical cross-section are considered.