Applications of bioinspired approaches and challenges in medical devices

Chen, Huawei; Zhang, Yi; Zhang, Liwen; Ding, Xuhua; Zhang, Deyuan

doi:10.1007/s42242-020-00103-6

Cited by 20 publications

(10 citation statements)

References 9 publications

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“…Although numerous proof-of-concept demonstrations have been presented in the relevant literature, the challenges detailed below should be addressed to realize the true potential of wearable sweat sensing technologies [130,131].…”

Section: Discussionmentioning

confidence: 99%

Emerging wearable flexible sensors for sweat analysis

et al. 2021

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Sweat, as a biofluid with the potential for noninvasive collection, provides profound insights into human health conditions, because it contains various chemicals and information to be utilized for the monitoring of well-being, stress levels, exercise, and nutrition. Recently, wearable sweat sensors have been developed as a promising substitute to conventional laboratory sweat detection methods. Such sensors are promising to realize low-cost, real-time, in situ sweat measurements, and provide great opportunities for health status evaluation analysis based on personalized big data. This review first presents an overview of wearable sweat sensors from the perspective of basic components, including materials and structures for specific sensing applications and modalities. Current strategies and specific methods of the fabrication of wearable power management are also summarized. Finally, current challenges and future directions of wearable sweat sensors are discussed.

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Section: Discussionmentioning

confidence: 99%

Emerging wearable flexible sensors for sweat analysis

et al. 2021

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“…Bioinspired structure-guided tissue/cell in vivo growth or vitro culturing tissue/ cell in vivo growth and in vitro culturing are remarkably important for implantable medical devices and drug evaluation [13]. To achieve desired growth and reproduction, it is necessary to construct the culturing conditions and the growing structure as close to living being as possible.…”

Section: Introductionmentioning

confidence: 99%

Perspective Chapter: Design and Characterization of Natural and Synthetic Soft Polymeric Materials with Biomimetic 3D Microarchitecture for Tissue Engineering and Medical Applications

Huang¹,

Shiotsuki²

2023

Biomedical Engineering

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Continuous work and developments in biomedical materials used in three-dimensional (3D) bioprinting have contributed to significant growth of 3D bioprinting applications in the production of personalized tissue-repairing membrane, skin graft, prostheses, medication delivery system, and 3D tissue engineering and regenerative medicine scaffolds. The design of clinic products and devices focus on new natural and synthetic biomedical materials employed for therapeutic applications in different 3D bioprinting technologies. Design and characterization of natural and synthetic soft polymeric materials with biomimetic 3D microarchitecture were considered. The natural soft polymeric materials would focus on new design bioinspired membranes containing supercritical fluids-decellularized dermal scaffolds for 3D bioprinting potential applications. Synthetic soft polymeric materials would focus on bioinspired polyvinyl alcohol (b-PVA) matrix with structural foam-wall microarchitectures. Characterization, thermal stability, and cell morphology of the b-PVA and the corresponding collagen-modified b-PVA were employed to evaluate their potential tissue engineering applications. Also, the b-PVA materials were conductive to HepG2 cells proliferation, migration, and expression, which might serve as a promising liver cell culture carrier to be used in the biological artificial liver reactor. TGA, DTG, DSC, SEM, and FTIR were employed to build up the effective system identification approach for biomimetic structure, stability, purity, and safety of target soft matrix.

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“…After touching tissue fluids, the grasping force of medical latex gloves 5,6 was found to be dramatically impaired. In the promising field of wearable flexible electronics, 7 probe detachment due to sweat accumulation inside the surfaces has become problematic over the years. Therefore, it is essential to improve the friction of soft tribo-contacts, which are prone to undesirable slipping under wet conditions.…”

Section: Introductionmentioning

confidence: 99%