Applications of coupled LC‐GC: A review

Abstract

Although coupled liquid chromatographygas chromatography (LC‐GC) was first demonstrated ten years ago, only in the last few years has there been a sudden surge of interest in the technique. Approximately 70% of the total number of LC‐GC applications have been published in the last two years (1987–88) alone. This review categorizes LC‐GC publications into four main application areas: fossil fuels, foods, environmental samples, biologiical/pharmaceutical samples, and miscellaneous samples. Multidimensional separations carried out using other coupled‐column chromatographic techniques (such as supercritical fluid chromatography (SFC) with GC, and on‐line trace enrichment‐GC) have also been included in this review.

Essential oil yield and quality of methyl eugenol rich Ocimum tenuiflorum L.f. (syn. O. sanctum L.) grown in south India as influenced by method of harvest

“…The homologous series of n-alkanes C 8 -C 22 , Poly Science Inc., Niles, USA, were used as standard.) with literature data [24], peak enrichment on co-injection with authentic compounds, comparison of mass spectra of the peaks with those of standard compounds reported in literature [25]. Quantitative data was obtained by electronic integration of peak areas (FID) without the use of response correction factors.…”

Coupled High Performance Liquid Chromatography with High Resolution Gas Chromatography

“…Recently, many authors have reviewed in some detail the various LC-GC transfer methods that are now available (1,(43)(44)(45)(46)(47)(48)(49)(50)(51)(52). For the analysis of normal phase eluents, the main transfer technique used is, without doubt, concurrent eluent evaporation employing a loop-type interface.…”

Sample Preparation for Chromatographic Analysis

“…The separation mechanisms in liquid chromatography and gas chromatography are complementary providing a powerful combined tool for the separation of complex mixtures [203,[223][224][225][226][227]. The combined technique is well suited to the analysis of a single component or of components of similar characteristics, forming a single peak or narrow fraction in the liquid chromatogram.…”