Applications of lipidomics in goat meat products: Biomarkers, structure, nutrition interface and future perspectives

Jia, Wei; Di, Chenna; Shi, Lin

doi:10.1016/j.jprot.2022.104753

Cited by 43 publications

(18 citation statements)

References 77 publications

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“…The above research information related to the mechanism of oil oxidation is helpful in developing methods against oil oxidation in food. The positional isomers and cis/trans isomers of HPODE were analyzed by LC-MS/MS using chiral columns and alkali metals (i.e., sodium ions) ( Jia, Di, & Shi, 2023 ). The combination of the LC-MS/MS with lipase enabled the understanding of oil oxidation mechanisms (i.e.…”

Section: Oil Oxidation Mechanism and Inhibition Strategymentioning

confidence: 99%

RETRACTED: Integrated the embedding delivery system and targeted oxygen scavenger enhances free radical scavenging capacity

2023

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Section: Oil Oxidation Mechanism and Inhibition Strategymentioning

confidence: 99%

RETRACTED: Integrated the embedding delivery system and targeted oxygen scavenger enhances free radical scavenging capacity

2023

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“…The difference of the same flavor Baijiu may be due to the different storage containers or storage conditions that have different effects on the physical and chemical reactions in the liquor body, leading to the inconsistency of the dominant chemical reactions. With regard to the question of which substances can be used as aging markers of certain flavor Baijiu, it is necessary to conduct a lot of research on this flavor Baijiu to find the rules ( Jia, Di, & Shi, 2023a ).…”

Section: Baijiu System Variation During Aging Periodmentioning

confidence: 99%

Synergy of physicochemical reactions occurred during aging for harmonizing and improving flavor

Jia

et al. 2023

Food Chemistry: X

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“…It had been demonstrated that trypsin was the serine-type protease having hydrophobic-type pockets with active centers (aspartic acid residues) located on the inner side and was suitable for the binding of long lysine residue and arginine residue, given the deep pocket. 53 In addition, quantitative results indicated that the concentrations of peptides (ranging from 105.9 ± 2.8 to 425.6 ± 13.1 mg kg −1 Figure S2a) and amino acids (ranging from 15.1 ± 0.5 to 33.7 ± 1.0 mg kg −1 , Figure S2b) in postbiotic supplementation group were significantly higher than those in the control term, suggesting that the activity of protease was evaluated.…”

Section: Journal Of Agricultural Andmentioning

confidence: 99%

Lactobacillus casei-Derived Postbiotics Elevate the Bioaccessibility of Proteins via Allosteric Regulation of Pepsin and Trypsin and Introduction of Endopeptidases

Fan

Jia

2023

J. Agric. Food Chem.

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The potential of probiotics to benefit digestion has been widely reported, while its utilization in high-risk patients and potential adverse reactions have focused interest on postbiotics. A variable data-independent acquisition (vDIA)-based spatial-omics strategy integrated with unsupervised variational autoencoders was applied to profile the functional mechanism underlying the action of Lactobacillus casei-derived postbiotic supplementation in goat milk digestion in an infant digestive system, from a metabolomics− peptidomics−proteomics perspective. Amide and olefin derivatives were proved to elevate the activities of pepsin and trypsin through hydrogen bonding and hydrophobic forces based on allosteric effects, and recognition of nine endopeptidases and their cleavage to serine, proline, and aspartate were introduced by postbiotics, thereby promoting the generation of hydrophilic peptides and elevating the bioaccessibility of goat milk protein. The peptides originating from αs1-casein, β-casein, β-lactoglobulin, Ig-like domain-containing protein, κ-casein, and serum amyloid A protein, with multiple bioactivities including angiotensin I-converting enzyme (ACE)-inhibitory, osteoanabolic, dipeptidyl peptidase IV (DPP-IV) inhibitory, antimicrobial, bradykinin-potentiating, antioxidant, and anti-inflammatory activities, were significantly increased in the postbiotic supplementation group, which was also considered to potentially prevent necrotizing enterocolitis through inhibiting the multiplication of pathogenic bacteria and blocking signal transducer and activator of transcription 1 and nuclear factor kappa-light-chain-enhancer of activated B cells inflammatory pathways. This research deepened the understanding of the mechanism underlying the postbiotics affecting goat milk digestion, which established a critical groundwork for the clinical application of postbiotics in infant complementary foods.

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Applications of lipidomics in goat meat products: Biomarkers, structure, nutrition interface and future perspectives

Cited by 43 publications

References 77 publications

RETRACTED: Integrated the embedding delivery system and targeted oxygen scavenger enhances free radical scavenging capacity

RETRACTED: Integrated the embedding delivery system and targeted oxygen scavenger enhances free radical scavenging capacity

Synergy of physicochemical reactions occurred during aging for harmonizing and improving flavor

Lactobacillus casei-Derived Postbiotics Elevate the Bioaccessibility of Proteins via Allosteric Regulation of Pepsin and Trypsin and Introduction of Endopeptidases

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