Abstract. In this paper, (p, q)-calculus is applied to construct (p, q)-analogue of divided differences. Another equivalent form of (p, q)-Bernstein operators which generalize the Phillips q-Bernstein polynomials are defined in terms of (p, q)-divided differences. It is shown that these operators reproduce constant as well as linear test functions. Further, we show that the difference of two consecutive (p, q)-Bernstein polynomials of a function f can be expressed in terms of second-order divided differences of f .