Applications of smartphones in analysis: Challenges and solutions

Jesus, Jemmyson Romário de; Ferrão, Marco Flôres; Costa, Adilson Ben da; Helfer, Gilson Augusto; Arruda, Marco Aurélio Zezzi

doi:10.1016/b978-0-12-823696-3.00009-x

Cited by 2 publications

(1 citation statement)

References 74 publications

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“…Additionally, it may not provide specific chemical identification or quantification without complementary analytical methods (Jaiswal et al., 2023; Mishra et al., 2017). Smartphone technologies present challenges related to calibration, data standardization, user error or bias, as well as concerns around data privacy and security (de Jesus et al., 2021).…”

Section: Techniques For Detecting Microbial and Chemical Hazards In C...mentioning

confidence: 99%

Microbiological and chemical hazards in cultured meat and methods for their detection

Sogore,

Guo,

Sun

et al. 2024

Comp Rev Food Sci Food Safe

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Cultured meat, which involves growing meat in a laboratory rather than breeding animals, offers potential benefits in terms of sustainability, health, and animal welfare compared to conventional meat production. However, the cultured meat production process involves several stages, each with potential hazards requiring careful monitoring and control. Microbial contamination risks exist in the initial cell collection from source animals and the surrounding environment. During cell proliferation, hazards may include chemical residues from media components such as antibiotics and growth factors, as well as microbial issues from improper bioreactor sterilization. In the differentiation stage where cells become muscle tissue, potential hazards include residues from scaffolding materials, microcarriers, and media components. Final maturation and harvesting stages risk environmental contamination from nonsterile conditions, equipment, or worker handling if proper aseptic conditions are not maintained. This review examines the key microbiological and chemical hazards that must be monitored and controlled during the manufacturing process for cultured meats. It describes some conventional and emerging novel techniques that could be applied for the detection of microbial and chemical hazards in cultured meat. The review also outlines the current evolving regulatory landscape around cultured meat and explains how thorough detection and characterization of microbiological and chemical hazards through advanced analytical techniques can provide crucial data to help develop robust, evidence‐based food safety regulations specifically tailored for the cultured meat industry. Implementing new digital food safety methods is recommended for further research on the sensitive and effective detection of microbiological and chemical hazards in cultured meat.

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Section: Techniques For Detecting Microbial and Chemical Hazards In C...mentioning

confidence: 99%

Microbiological and chemical hazards in cultured meat and methods for their detection

Sogore,

Guo,

Sun

et al. 2024

Comp Rev Food Sci Food Safe

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Swellable Biopolymer Composite Microneedle Patch for Pain‐Free Collection of Interstitial Fluid to Analyze Multiple Biomolecules

Chauhan,

Prasad,

Venuganti

2024

J Biomedical Materials Res

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Sampling of interstitial fluid (ISF) using microneedle (MN) patch offers a pain‐free minimally invasive alternative to syringe needle‐based blood sample collection. However, there is a challenge in the development of MN patch that provides swelling behavior with sufficient mechanical strength for skin penetration. Here, we report fabrication of MN patch made of biopolymer composite containing iota‐carrageenan, gelatin, and polyethylene glycol. Calcium chloride was used as a crosslinker to improve mechanical strength. MN patch was characterized for integrity, swelling behavior, mechanical strength, aspiration of fluid from agarose gel, and the excised porcine ear skin. An array of 361 MNs was able to aspirate 36 ± 5 and 14 ± 1 μL fluid after application in agarose gel matrix and the ex vivo porcine skin model, respectively. MN patch applied in vivo rat model for 30 min resulted in the collection of ISF containing 267 ± 128 mg/dL, 24 ± 13 mg/dL, and 0.6 ± 0.4 mIU/mL of glucose, uric acid and thyroid stimulating hormone (TSH), respectively. The concentration of glucose, uric acid, and TSH in rat blood was found to be 199 ± 47 mg/dL, 8.4 ± 6 mg/dL, and 1.1 ± 0.6 mIU/mL at the same time. Furthermore, MN patch applied on the forearm of 10 healthy human volunteers for 30 min was able to aspirate 32 ± 14 μL of ISF. The concentration of glucose, uric acid, and TSH determined from ISF samples of human volunteers was 64 ± 25 mg/dL, 4.2 ± 4.1 mg/dL, and 0.16 ± 0.08 mIU/mL, respectively. The visual analogue scale (VAS) pain score after MN application was lower compared with hypodermic syringe needle insertion. Taken together, biopolymer composite‐based swellable MN patch can be developed for collection of ISF for simultaneous determination of multiple biomolecules in a minimally invasive manner.

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Applications of smartphones in analysis: Challenges and solutions

Cited by 2 publications

References 74 publications

Microbiological and chemical hazards in cultured meat and methods for their detection

Microbiological and chemical hazards in cultured meat and methods for their detection

Swellable Biopolymer Composite Microneedle Patch for Pain‐Free Collection of Interstitial Fluid to Analyze Multiple Biomolecules

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