Introduction: Developing the musculoskeletal complaints in music students are common because of practice over an instrument. Little is known about the effectiveness of interventions; therefore, more research is necessary to better understand and manage the issues; therefore, the present study was aimed at evaluating the impact of 6-week intervention program on posture in music students.Materials and Methods: 6-week intervention program was carried out six weeks, aiming for 30 female music students: (i) Experimental group (n = 15) (58.50 kg, 168.50 cm, 20.40 years); (ii) Control group (n = 15) (60.20 kg, 170.20 cm, 20.80 kg), attending the bachelor's degree in Performing Arts. Standardized measure to evaluate the posture was carried out; in particular, pre-(31-10, Week 1) and post-testing (9-12, Week 6). Evaluating the impact of 6-week intervention program was by Wilcoxon Signed-Rank Test, Wilcoxon Rank-Sum Test (rejection of normality of data distribution), Pearson's r (normality of data distribution).Results. Significant differences (.01, .05) between the experimental and control group were in: (i) Pre-testing -(i-i) Head and neck; (i-ii) Curvature of spine; (ii) Post-testing -(ii-i) Head and neck; (ii-ii) Abdomen and pelvis; (ii-iii) Curvature of spine; (ii-iiii) Shoulders and scapulas. 6-week intervention program, targeting the posture in music students is important because of its impact on musculoskeletal health.Discussions: 6-week intervention program in music students was effective at improving their postures; and therefore, implementing intervention program (at least 6 weeks) in music students and guidance on prevention of musculoskeletal complaints may influence, in a positive way, their quality of life and career.